Frances K Wiseman

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Down syndrome--recent progress and future prospects
    Frances K Wiseman
    Department of Neurodegenerative Disease, Institute of Neurology, Queen Square, London, UK
    Hum Mol Genet 18:R75-83. 2009
  2. pmc Generation of a panel of antibodies against proteins encoded on human chromosome 21
    Frances K Wiseman
    Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK
    J Negat Results Biomed 9:7. 2010
  3. pmc Mouse models of aneuploidy
    Olivia Sheppard
    Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK
    ScientificWorldJournal 2012:214078. 2012
  4. pmc Altered regulation of tau phosphorylation in a mouse model of down syndrome aging
    Olivia Sheppard
    University College London Institute of Neurology, London, UK
    Neurobiol Aging 33:828.e31-44. 2012
  5. doi request reprint Cognitive enhancement therapy for a model of Down syndrome
    Frances K Wiseman
    Department of Neurodegenerative Disease, University College London, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Sci Transl Med 1:7ps9. 2009
  6. pmc Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain
    Jon O Cleary
    Centre for Advanced Biomedical Imaging, Department of Medicine and Institute of Child Health, University College London, London, UK
    Neuroimage 56:974-83. 2011

Collaborators

Detail Information

Publications6

  1. pmc Down syndrome--recent progress and future prospects
    Frances K Wiseman
    Department of Neurodegenerative Disease, Institute of Neurology, Queen Square, London, UK
    Hum Mol Genet 18:R75-83. 2009
    ..In particular, the use of chromosome engineering to generate new trisomic mouse models and large-scale studies of genotype-phenotype relationships in patients are likely to significantly contribute to the future understanding of DS...
  2. pmc Generation of a panel of antibodies against proteins encoded on human chromosome 21
    Frances K Wiseman
    Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK
    J Negat Results Biomed 9:7. 2010
    ..To this end, we have generated a panel of antibodies raised against proteins encoded by genes on human chromosome 21 that are known to be expressed in the adult brain of Tc1 mice..
  3. pmc Mouse models of aneuploidy
    Olivia Sheppard
    Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK
    ScientificWorldJournal 2012:214078. 2012
    ..Thus, creating and studying mouse models of aneuploidy and copy number variation is important for understanding what it is to be human, in both the normal and genomically altered states...
  4. pmc Altered regulation of tau phosphorylation in a mouse model of down syndrome aging
    Olivia Sheppard
    University College London Institute of Neurology, London, UK
    Neurobiol Aging 33:828.e31-44. 2012
    ..It is possible that a similar mechanism may also occur in people with DS...
  5. doi request reprint Cognitive enhancement therapy for a model of Down syndrome
    Frances K Wiseman
    Department of Neurodegenerative Disease, University College London, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Sci Transl Med 1:7ps9. 2009
    ..This study highlights the function of the norepinephrine-ergic system in Down syndrome and suggests possible treatment options for people with Down syndrome...
  6. pmc Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain
    Jon O Cleary
    Centre for Advanced Biomedical Imaging, Department of Medicine and Institute of Child Health, University College London, London, UK
    Neuroimage 56:974-83. 2011
    ....