Research Topics
| A P R WilsonSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Recommendations for surveillance priorities for healthcare-associated infections and criteria for their conductA P R Wilson
Department of Clinical Microbiology, University College London Hospitals, 46 Cleveland Street, London W1T 4JF, UK
J Antimicrob Chemother 67:i23-8. 2012..Mandatory reporting of bacteraemia due to E. coli and MSSA were introduced during 2011 and further extension of surveillance is likely...
In vitro susceptibility of Gram-positive pathogens to linezolid and teicoplanin and effect on outcome in critically ill patientsA Peter R Wilson
Department of Clinical Microbiology, University College London Hospitals, 46 Cleveland Street, London W1T 4JF, UK
J Antimicrob Chemother 58:470-3. 2006..To determine the prevalence of teicoplanin and linezolid resistance amongst Gram-positive pathogens isolated in the intensive care unit (ICU) and the impact of any resistance on clinical outcome...
Postoperative surveillance, registration and classification of wound infection in cardiac surgery--experiences from Great BritainA P R Wilson
Department of Clinical Microbiology, University College London Hospitals, London, UK
APMIS 115:996-1000. 2007..Often highlighting the problem is sufficient to reverse the trend, but the process of audit and control is becoming more important as accountability and performance is demanded by primary care providers and patients...
Reducing hospital-acquired infection by design: the new University College London HospitalA P R Wilson
University College London Hospitals, London, UK
J Hosp Infect 62:264-9. 2006..Stockley JM, Constantine CE, Orr KE, The Association of Medical Microbiologists' New Hospital Developments Project Group. Building new hospitals: a UK infection control perspective...
Laboratory and in-use assessment of methicillin-resistant Staphylococcus aureus contamination of ergonomic computer keyboards for ward useA Peter R Wilson
Department of Microbiology, University College London Hospitals, London, UK
Am J Infect Control 36:e19-25. 2008..An ideal computer keyboard for clinical use would be easily cleanable and cleaned by staff, meet acceptable levels of usability, and not attract hospital bacteria...
The impact of enhanced cleaning within the intensive care unit on contamination of the near-patient environment with hospital pathogens: a randomized crossover study in critical care units in two hospitalsA Peter R Wilson
Departments of Microbiology and Infection Control, University College London Hospitals, London, United Kingdom
Crit Care Med 39:651-8. 2011..To determine the effect of enhanced cleaning of the near-patient environment on the isolation of hospital pathogens from the bed area and staff hands...
Surgical wound infection as a performance indicator: agreement of common definitions of wound infection in 4773 patientsA P R Wilson
Department of Clinical Microbiology, University College London Hospitals, London WC1E 6DB
BMJ 329:720. 2004..To assess the level of agreement between common definitions of wound infection that might be used as performance indicators...
Is natural ventilation a useful tool to prevent the airborne spread of TB?Peter Wilson
Windeyer Institute of Medical Sciences, University College London Hospitals, London, United Kingdom
PLoS Med 4:e77. 2007
Impact of rapid molecular screening for meticillin-resistant Staphylococcus aureus in surgical wardsM R S Keshtgar
Department of Surgery, Windeyer Institute of Medical Sciences, University College London Hospitals Foundation Trust, London, UK
Br J Surg 95:381-6. 2008..This study aimed to establish the feasibility and cost-effectiveness of rapid molecular screening for hospital-acquired meticillin-resistant Staphylococcus aureus (MRSA) in surgical patients within a teaching hospital...
Effect of surface coating and finish upon the cleanability of bed rails and the spread of Staphylococcus aureusS Ali
Department of Clinical Microbiology, University College London Hospital, London, UK
J Hosp Infect 80:192-8. 2012..Bacterial reservoirs in the near-patient environment are likely vectors of healthcare-acquired infection...
Ward assessment of SmartIdeas Project: bringing source isolation to the patientG Moore
Department of Clinical Microbiology, University College London Hospitals, London, UK
J Hosp Infect 76:103-7. 2010..The finding was confirmed by aerobiology tests at the Health Protection Agency Laboratory, Porton Down, UK. A trial of redesigned units is required to establish efficacy (Trial Identifier: ISRCTN02681602)...
Reduction in wound infection rates by wound surveillance with postdischarge follow-up and feedbackA P R Wilson
Department of Clinical Microbiology, University College London Hospitals, London, UK
Br J Surg 93:630-8. 2006..CONCLUSION: Wound surveillance was associated with a reduction in rates of wound infection within 4 years. The cost reduction as a result of fewer infections exceeded the cost of surveillance after 2 years...
Linezolid versus teicoplanin in the treatment of Gram-positive infections in the critically ill: a randomized, double-blind, multicentre studyJorge A Cepeda
Department of Clinical Microbiology, Pharmacy Department, University College London Hospitals, Grafton Way, London WC1E 6DB, UK
J Antimicrob Chemother 53:345-55. 2004..CONCLUSIONS: Linezolid has similar safety and efficacy to teicoplanin in treating Gram-positive infections in the critically ill. Short-term MRSA clearance achieved with linezolid suggests better skin and mucosal penetration...
Monitoring the occurrence of wound infections after cardiac surgeryC Sherlaw-Johnson
University College London, London, UK
J Hosp Infect 65:307-13. 2007..If used in real-time, problems with the care process can be quickly identified allowing timely remedial action to be taken...
Comparison of four methods for detection of teicoplanin resistance in methicillin-resistant Staphylococcus aureusR Charlesworth
Department of Clinical Microbiology, University College London Hospitals, Windeyer Institute of Medical Sciences, London W1T 4JF, UK
J Antimicrob Chemother 58:186-9. 2006..CONCLUSIONS: Neither disc diffusion nor the VITEK systems are reliable for detection of teicoplanin resistance in MRSA. Etest and agar incorporation remain the methods of choice...
The use of adenosine triphosphate bioluminescence to assess the efficacy of a modified cleaning program implemented within an intensive care settingGinny Moore
Department of Microbiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
Am J Infect Control 38:617-22. 2010..A total environmental cleaning system based on microfiber technology was implemented within 2 intensive care units (ICUs). The efficacy of this modified cleaning program was assessed using adenosine triphosphate (ATP) bioluminescence...
Automating the monitoring of surgical site infections using variable life-adjusted display chartsC Vasilakis
Clinical Operational Research Unit, University College London, London, UK
J Hosp Infect 79:119-24. 2011..We recommend adopting the tool and VLAD charts wherever surgical site surveillance is continuous...
Pharmacokinetic studies of linezolid and teicoplanin in the critically illTony Whitehouse
Bloomsbury Institute of Intensive Care Medicine, Department of Medicine, University College London, London, UK
J Antimicrob Chemother 55:333-40. 2005..For teicoplanin, further study is needed to confirm if a trough of 10 mg/L is associated with a higher rate of cure than 5 mg/L. If so, serum drug assays would be needed to ensure a therapeutic level...
Short-course monotherapy strategy for treating bacteremia in the critically illA Corona
Bloomsbury Institute of Intensive Care Medicine, University College, London, UK
Minerva Anestesiol 72:841-57. 2006..g. endocarditis, osteomyelitis). The aim of this study is to assess our policy by monitoring the clinical response, relapse rate and patient outcome...
Is the MIC useful in deciding to treat endocarditis surgically?B I Walton
Department of Cardiology, University College London Hospitals, London, UK
Int J Antimicrob Agents 23:394-7. 2004..There were no significant differences between bacterial pathogens in mortality, surgical referral or cure by medical treatment. The measurement of MIC appears prognostically important in deciding the surgical management of endocarditis...
Laundering of hospital staff uniforms at homeS N Patel
Department of Clinical Microbiology, Windeyer Institute of Medical Sciences, University College London Hospital, 46 Cleveland Street, London W1T 4JF, UK
J Hosp Infect 62:89-93. 2006..Domestic laundering of uniforms is an acceptable alternative to hospital laundering if combined with tumble drying or ironing...
The efficacy of the inorganic copper-based biocide CuWB50 is compromised by hard waterG Moore
Department of Microbiology, University College Hospitals NHS Foundation Trust, London, UK
Lett Appl Microbiol 46:655-60. 2008..We sought to explain the unexpected failure of the inorganic copper-based biocide CuWB50 to effectively decontaminate microfibre cleaning cloths that became contaminated with Acinetobacter lwoffii...
Isolation of patients in single rooms or cohorts to reduce spread of MRSA in intensive-care units: prospective two-centre studyJorge A Cepeda
Department of Clinical Microbiology, University College London Hospitals, London W1T 4 JF, UK
Lancet 365:295-304. 2005....
How will surgical site infection be measured to ensure "high quality care for all"?E Ashby
Chelsea and Westminster Hospital, 269 Fulham Road, London, UK
J Bone Joint Surg Br 92:1294-9. 2010..If different methods are used, direct comparisons will be invalid and published rates of infection will be misleading...
Prospective audit of bacteraemia management in a university hospital ICU using a general strategy of short-course monotherapyAlberto Corona
Bloomsbury Institute of Intensive Care Medicine, University College London, Jules Thorn Building, Middlesex Hospital, Mortimer Street, London W1N 3AA
J Antimicrob Chemother 54:809-17. 2004..g. endocarditis, osteomyelitis). We decided to assess this approach for treating community-, hospital-, and ICU-acquired bacteraemia by monitoring clinical response, relapse rate and patient outcome...
Effect of linezolid and teicoplanin on skin staphylococciSamantha Hayman
J Antimicrob Chemother 59:1281-2. 2007
Teicoplanin resistance in methicillin-resistant Staphylococcus aureus in an intensive care unitJorge Cepeda
J Antimicrob Chemother 52:533-4. 2003
