Roger S Williams

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Acute liver failure--practical management
    Roger Williams
    Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London, WC1E 6HX, UK
    Acta Gastroenterol Belg 70:210-3. 2007
  2. doi request reprint The pervading influence of alcoholic liver disease in hepatology
    Roger Williams
    Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London, WC1E 6HX, UK
    Alcohol Alcohol 43:393-7. 2008
  3. ncbi request reprint Living related adult-to-adult liver transplantation: meeting the donor shortage
    R Williams
    Liver Unit, Cromwell Hospital, London, UK
    Antiviral Res 52:217-23. 2001
  4. ncbi request reprint Hepatology: a personal story
    Roger Williams
    Institute of Hepatology, University College London
    Clin Med 8:25-8. 2008
  5. ncbi request reprint Global challenges in liver disease
    Roger Williams
    UCL Institute of Hepatology, Division of Medicine, Royal Free and University College Medical School, London, UK
    Hepatology 44:521-6. 2006
  6. ncbi request reprint Hepatitis C in 2006
    Roger Williams
    The UCL Institute of Hepatology, University College London Medical School, London, UK
    Eur J Gastroenterol Hepatol 18:309-11. 2006
  7. ncbi request reprint 15th Seah Cheng Siang Memorial Lecture: Liver transplantation--lessons learnt and future horizons
    R Williams
    The UCL Institute of Hepatology, Royal Free and University College Medical School, 69 75 Chenies Mews, London WC1E 6HX, UK
    Ann Acad Med Singapore 34:689-97. 2005
  8. ncbi request reprint Adult-to-adult living donor liver transplant: UK experience
    Roger S Williams
    Liver Unit Cromwell Hospital, University College London Hospitals, London, UK
    Eur J Gastroenterol Hepatol 15:7-14. 2003
  9. ncbi request reprint Evaluation of the efficacy and safety of rifaximin in the treatment of hepatic encephalopathy: a double-blind, randomized, dose-finding multi-centre study
    R Williams
    Liver Research Unit, King s College Hospital, London, UK
    Eur J Gastroenterol Hepatol 12:203-8. 2000
  10. ncbi request reprint Acute liver failure: established and putative hepatitis viruses and therapeutic implications
    R Williams
    Institute of Hepatology, University College London and University College London Hospitals, England
    J Gastroenterol Hepatol 15:G17-25. 2000

Detail Information

Publications65

  1. ncbi request reprint Acute liver failure--practical management
    Roger Williams
    Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London, WC1E 6HX, UK
    Acta Gastroenterol Belg 70:210-3. 2007
    ....
  2. doi request reprint The pervading influence of alcoholic liver disease in hepatology
    Roger Williams
    Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London, WC1E 6HX, UK
    Alcohol Alcohol 43:393-7. 2008
    ..Even as the stringent regulatory measures needed to control rising alcohol consumption are introduced by government, the burden of liver disease in the UK will remain high for years to come...
  3. ncbi request reprint Living related adult-to-adult liver transplantation: meeting the donor shortage
    R Williams
    Liver Unit, Cromwell Hospital, London, UK
    Antiviral Res 52:217-23. 2001
    ....
  4. ncbi request reprint Hepatology: a personal story
    Roger Williams
    Institute of Hepatology, University College London
    Clin Med 8:25-8. 2008
    ..The new liver support devices are currently showing promise but on the negative side is the rising prevalence of alcohol-related liver disease and non-alcoholic fatty liver disease...
  5. ncbi request reprint Global challenges in liver disease
    Roger Williams
    UCL Institute of Hepatology, Division of Medicine, Royal Free and University College Medical School, London, UK
    Hepatology 44:521-6. 2006
    ..Only through a concerted effort from governments, health agencies, healthcare professionals at all levels, and the pharmaceutical industry can this grim outlook for liver disease worldwide be reversed...
  6. ncbi request reprint Hepatitis C in 2006
    Roger Williams
    The UCL Institute of Hepatology, University College London Medical School, London, UK
    Eur J Gastroenterol Hepatol 18:309-11. 2006
  7. ncbi request reprint 15th Seah Cheng Siang Memorial Lecture: Liver transplantation--lessons learnt and future horizons
    R Williams
    The UCL Institute of Hepatology, Royal Free and University College Medical School, 69 75 Chenies Mews, London WC1E 6HX, UK
    Ann Acad Med Singapore 34:689-97. 2005
    ..Living donor liver transplantation has also come to the fore, and to minimise potential harm to the donor, new techniques are being developed which will allow greater use of left lobe grafts...
  8. ncbi request reprint Adult-to-adult living donor liver transplant: UK experience
    Roger S Williams
    Liver Unit Cromwell Hospital, University College London Hospitals, London, UK
    Eur J Gastroenterol Hepatol 15:7-14. 2003
    ..The present report describes the first UK experience with the procedure in patients from overseas who have the lowest priority for cadaver organ allocation...
  9. ncbi request reprint Evaluation of the efficacy and safety of rifaximin in the treatment of hepatic encephalopathy: a double-blind, randomized, dose-finding multi-centre study
    R Williams
    Liver Research Unit, King s College Hospital, London, UK
    Eur J Gastroenterol Hepatol 12:203-8. 2000
    ..To determine the efficacy, tolerability and safety of oral rifaximin given at three dose levels in patients with cirrhosis and mild to moderate hepatic encephalopathy (HE)...
  10. ncbi request reprint Acute liver failure: established and putative hepatitis viruses and therapeutic implications
    R Williams
    Institute of Hepatology, University College London and University College London Hospitals, England
    J Gastroenterol Hepatol 15:G17-25. 2000
    ....
  11. ncbi request reprint Review article: bacterial flora and pathogenesis in hepatic encephalopathy
    R Williams
    The UCL Institute of Hepatology, Royal Free and University College Medical School, University College London, UK
    Aliment Pharmacol Ther 25:17-22. 2007
    ..Considered together, these data suggest wide-ranging pathophysiological contributions of bacteria to hepatic encephalopathy and underline the potential for an integral role of antibiotics and other bactericidal agents in its management...
  12. ncbi request reprint Clinical recurrence of hepatitis A following liver transplantation for acute liver failure
    E Gane
    Institute of Liver Studies, King s College Hospital, London, United Kingdom
    J Med Virol 45:35-9. 1995
    ..The possible interaction with hepatitis A may have delayed the appearance of hepatitis C. Administration of HAV immunoglobulin at the time of transplantation should be considered in all cases of HAV-related fulminant hepatic failure...
  13. ncbi request reprint Novel immunoassay for the detection of hepatitis B surface 'escape' mutants and its application in liver transplant recipients
    S Ijaz
    Department of Virology, Royal Free and University College Medical School, Windeyer Institute of Medical Sciences, London, England
    J Med Virol 63:210-6. 2001
    ..This serological approach allows rapid and cost-effective screening for HBsAg escape mutants in the liver transplant setting and may be helpful in the selection of appropriate prophylaxis...
  14. ncbi request reprint Quality of life after liver transplantation for alcoholic liver disease
    S P Pereira
    Institute of Liver Studies, King s College School of Medicine and Dentistry, London, UK
    Liver Transpl 6:762-8. 2000
    ..Overall, the quality of life after liver transplantation for ALD is high and broadly similar to the levels expected in the normal population...
  15. pmc Frequency of hepatic HBV-DNA in patients with cirrhosis and hepatocellular carcinoma: relation to serum HBV markers
    Y S White
    Liver Unit, King s College Hospital School of Medicine and Dentistry, London, UK
    Br J Cancer 61:909-12. 1990
    ..No sequences were found in any of the remaining 89 patients who were seronegative for all markers. Thus, liver HBV-DNA was only detected in the presence of a serum marker, usually HBsAg...
  16. pmc Liver transplantation for malignant disease. Results in 93 consecutive patients
    R J Polson
    Liver Unit, King s College Hospital, School of Medicine and Dentistry, London, England
    Ann Surg 207:373-9. 1988
    ..Despite the overall high frequency of tumor recurrence in most categories of hepatic malignancy, liver transplantation gave worthwhile survival with a number of patients cured and in the others considerable palliation of symptoms...
  17. ncbi request reprint Randomized trial of lamivudine versus hepatitis B immunoglobulin for long-term prophylaxis of hepatitis B recurrence after liver transplantation
    N V Naoumov
    Institute of Hepatology, University College London and UCL Hospitals, UK
    J Hepatol 34:888-94. 2001
    ..In a randomized trial we investigated a regimen where the initially given hepatitis B immunoglobulin (HBIg) is replaced by long-term lamivudine treatment...
  18. pmc Expansion of anti-AFP Th1 and Tc1 responses in hepatocellular carcinoma occur in different stages of disease
    S Behboudi
    Institute of Hepatology, University College London, UK
    Br J Cancer 102:748-53. 2010
    ..However, there is little information on the pattern of CD4 (Th1) and CD8 (Tc1) T-cell response to AFP in patients with HCC and their association with the clinical characteristics of patients...
  19. pmc Development and pilot evaluation of a complex intervention to improve experienced continuity of care in patients with cancer
    M King
    Department of Mental Health Sciences, Royal Free and University College Medical School, Royal Free Campus, London, UK
    Br J Cancer 100:274-80. 2009
    ..A phase III trial targeting patients with inadequate experienced continuity of care is recommended...
  20. ncbi request reprint Presence of a newly described human DNA virus (TTV) in patients with liver disease
    N V Naoumov
    Institute of Hepatology, Department of Medicine, University College London Medical School, UK
    Lancet 352:195-7. 1998
    ..We investigated the presence of this virus in patients with liver disease in the UK to find out whether TTV infection is associated with liver damage...
  21. ncbi request reprint Transdermal hormone replacement therapy improves vertebral bone density in primary biliary cirrhosis: results of a 1-year controlled trial
    S P Pereira
    Institute of Liver Studies, King s College Hospital, London, UK
    Aliment Pharmacol Ther 19:563-70. 2004
    ..Retrospective studies have suggested that hormone replacement therapy may reduce the rate of bone loss in primary biliary cirrhosis, but no controlled data are available...
  22. pmc Prospects for extracorporeal liver support
    R Jalan
    Liver Failure Group, Institute of Hepatology, University College London Medical School and University College London Hospitals, London UK
    Gut 53:890-8. 2004
  23. doi request reprint The use of complementary therapy by men with prostate cancer in the UK
    S Wilkinson
    Department of Mental Health Sciences, Royal Free and University College Medical School, The Hampstead Campus, London, UK
    Eur J Cancer Care (Engl) 17:492-9. 2008
    ..Clinicians need to be aware of the prevalence of CT use amongst patients with prostate cancer, considering the potential harm that could be caused by interactions with conventional treatments...
  24. pmc The effects of bilingualism on stuttering during late childhood
    P Howell
    Division of Psychology and Language Sciences, University College London, London, UK
    Arch Dis Child 94:42-6. 2009
    ..To examine stuttering by children speaking an alternative language exclusively (LE) or with English (BIL) and to study onset of stuttering, school performance and recovery rate relative to monolingual speakers who stutter (MONO)...
  25. ncbi request reprint Toga virus-like particles in acute liver failure attributed to sporadic non-A, non-B hepatitis and recurrence after liver transplantation
    E A Fagan
    Institute of Liver Studies, King s College Hospital, London, England, UK
    J Med Virol 38:71-7. 1992
    ..The agent may be novel because pre- and post-grafting sera were negative for antibodies against representative panels of arboviruses and in first and second generation antibody tests for hepatitis C virus...
  26. ncbi request reprint Development of autoimmune hepatitis following liver transplantation for primary biliary cirrhosis
    D E Jones
    Centre for Liver Research, University of Newcastle, Kings College Hospital, London, England
    Hepatology 30:53-7. 1999
    ..The finding, in each case, of a coincidental multiple HLA class I allele match between the recipient and their liver donor suggests that HLA class I-restricted mechanisms may play an important role in the pathogenesis of AIH...
  27. ncbi request reprint The systemic inflammatory response syndrome in acute liver failure
    N Rolando
    Institute of Liver Studies, Guy s King s and St Thomas Medical School, London, UK
    Hepatology 32:734-9. 2000
    ..In ALF, the SIRS, whether or not precipitated by infection, appears to be implicated in the progression of encephalopathy, reducing the chances of transplantation and conferring a poorer prognosis...
  28. ncbi request reprint Review article: the molecular adsorbents recirculating system (MARS) in liver failure
    S Sen
    Institute of Hepatology, University College London Medical School and University College London Hospitals, UK
    Aliment Pharmacol Ther 16:32-8. 2002
    ..Data regarding MARS experience in acute liver failure and in primary graft dysfunction are encouraging but limited. Its real usefulness in these settings is, at present, under evaluation in randomized controlled clinical trials...
  29. ncbi request reprint Non-cytolytic inhibition of hepatitis B virus replication in human hepatocytes
    D Suri
    Institute of Hepatology, University College London, 69-75 Chenies Mews, WC1E 6HX, London, UK
    J Hepatol 35:790-7. 2001
    ..CONCLUSIONS: These results provide direct evidence that IFN-gamma can inhibit both HBV transcription and replication in human hepatocytes without cell lysis...
  30. ncbi request reprint Institutional resource needs and optimising timing of living donor liver transplant
    R Williams
    Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London, WCIE 6HX, UK
    Transplant Proc 35:922-5. 2003
  31. ncbi request reprint Learning and new discovery with cyclosporine in the Cambridge-King's Programme: a personal view
    R Williams
    Institute of Hepatology, University College of London, London, UK
    Transplant Proc 36:261S-266S. 2004
    ..Whether 2-hour postdose monitoring with reduction in rejection frequency and toxicity as described recently better match results with tacrolimus in comparison-controlled trials remains to be determined...
  32. ncbi request reprint Low myo-inositol and high glutamine levels in brain are associated with neuropsychological deterioration after induced hyperammonemia
    D L Shawcross
    Institute of Hepatology, University College London, London, WC1E 6HX United Kingdom
    Am J Physiol Gastrointest Liver Physiol 287:G503-9. 2004
    ....
  33. ncbi request reprint Toga-like virus as a cause of fulminant hepatitis attributed to sporadic non-A, non-B
    E A Fagan
    Liver Unit, King s College Hospital, Denmark Hill, London, England
    J Med Virol 28:150-5. 1989
    ....
  34. pmc Hyperthyroxinaemia in hepatocellular carcinoma: relation to thyroid binding globulin in the clinical and preclinical stages of the disease
    A Alexopoulos
    Kings College Hospital School of Medicine and Dentistry, Denmark Hill, London, UK
    Br J Cancer 57:313-6. 1988
    ..The rises in TBG occurred prior to any clinical signs of tumour development and may be one of the earliest serological changes to occur during carcinogenesis in the cirrhotic liver...
  35. ncbi request reprint Serum F protein estimation in liver allograft recipients with graft dysfunction
    G M Forbes
    Liver Unit, King s College Hospital, London, England
    Transplantation 48:995-7. 1989
    ..048). Despite its high concentration in liver cells, this marker does not provide any additional benefit in the diagnosis of graft dysfunction or in monitoring liver allograft function following transplantation...
  36. ncbi request reprint Liver autoreactivity in acute virus A, B and non-A, non-B hepatitis
    S Vento
    Liver Unit, King s College Hospital, Denmark Hill, London, UK
    J Clin Lab Immunol 25:1-7. 1988
    ..These liver-specific autoreactions have the potential to contribute to hepatocellular damage in virus A and B hepatitis but it seems unlikely that autoimmunity plays a significant pathogenetic role in NANB viral infections...
  37. pmc Clinical efficacy and toxicity of standard dose adriamycin in hyperbilirubinaemic patients with hepatocellular carcinoma: relation to liver tests and pharmacokinetic parameters
    P J Johnson
    Institute of Liver Studies, King s College Hospital School of Medicine and Dentistry, London, UK
    Br J Cancer 65:751-5. 1992
    ..Whilst hyperbilirubinaemic patients may tolerate a full dose of Adriamycin, we found no evidence that this was associated with a better response rate, which was disappointingly low at only 18%...
  38. ncbi request reprint Evaluation of efficacy and safety of thymus humoral factor-gamma 2 in the management of chronic hepatitis B
    B A Farhat
    Institute of Liver Studies, King s College School of Medicine and Dentistry, London, UK
    J Hepatol 23:21-7. 1995
    ..We investigated the antiviral and immunomodulatory effects of a combination treatment using thymus humoral factor-gamma 2 and alpha-interferon in patients with chronic hepatitis B in whom previous monotherapy with interferon had failed...
  39. ncbi request reprint Orthotopic liver transplantation in the treatment of metastatic neuroendocrine tumors of the liver
    D Routley
    Institute of Liver Studies, King s College Hospital, London, England
    Liver Transpl Surg 1:118-21. 1995
    ..Although the tumor will recur in most cases, this is not necessarily associated with early return of symptoms. Prolonged disease free survival is more likely in the non carcinoid apudoma group...
  40. ncbi request reprint A community prevalence study of antibodies to hepatitis A and E in inner-city London
    W Bernal
    Institute of Liver Studies, King s College Hospital, London, United Kingdom
    J Med Virol 49:230-4. 1996
    ..8% in non-UK born subjects. The age-specific seroprevalence of the UK born group is suggestive of a cohort effect. The data suggest a low circulation of HEV in inner-city London, remaining uncommon relative to HAV...
  41. ncbi request reprint The effect of liver transplantation in a 13-year-old boy with erythropoietic protoporphyria
    R J Polson
    Liver Unit, King s College Hospital, London, United Kingdom
    Transplantation 46:386-9. 1988
    ..Following liver grafting these elevated porphyrin levels fell rapidly, with the red cell protoporphyrin level dropping to 10% of its preoperative value, and the rest returning to virtually normal within three months of operation...
  42. ncbi request reprint Graft dysfunction mimicking autoimmune hepatitis following liver transplantation in adults
    M A Heneghan
    Institute of Liver Studies, King's College Hospital, Denmark Hill, London, England
    Hepatology 34:464-70. 2001
    ..Graft loss may be a consequence. This entity may represent a specific type of rejection that should currently be classified as "graft dysfunction mimicking autoimmune hepatitis."..
  43. ncbi request reprint Response to cyproterone acetate treatment in primary hepatocellular carcinoma is related to fall in free 5 alpha-dihydrotestosterone
    A Forbes
    Liver Unit, King s College School of Medicine and Dentistry, Denmark Hill, London, U K
    Eur J Cancer Clin Oncol 23:1659-64. 1987
    ..This has been achieved in other conditions by the combination of CPA with low dose oestrogen or with LHRH agonists...
  44. ncbi request reprint Liver transplantation for primary and secondary hepatic apudomas
    J C Arnold
    Liver Unit, King s College Hospital, Cambridge, UK
    Br J Surg 76:248-9. 1989
    ..The other two patients died from chronic graft rejection 7 and 8 months after transplantation...
  45. pmc Autoantibodies to human cytosol: a marker of sporadic porphyria cutanea tarda
    Y Ma
    Institute of Hepatology, University College London, London, UK
    Clin Exp Immunol 126:47-53. 2001
    ..0001). In conclusion, anticytosolic antibodies, particularly to a 40-kDa polypeptide, are frequent in PCT and associated with HCV infection and severity of liver damage...
  46. doi request reprint Contemporary patterns of care and disease activity outcome in early rheumatoid arthritis: the ERAN cohort
    P Kiely
    Department of Rheumatology, St George s Healthcare NHS Trust, London, UK
    Rheumatology (Oxford) 48:57-60. 2009
    ..To report from the Early Rheumatoid Arthritis Network (ERAN), time from symptom onset to start of therapy, treatment choices and disease outcome in early RA...
  47. ncbi request reprint Serial study of liver-directed autoantibodies and autoreactive T-lymphocytes in acute viral hepatitis B
    S Vento
    Liver Unit, King s College School of Medicine and Dentistry, London, UK
    J Autoimmun 1:299-307. 1988
    ....
  48. ncbi request reprint Association of British Clinical Diabetologists (ABCD) survey of secondary care services for diabetes in the UK, 2000. 1. Methods and major findings
    P H Winocour
    East and North Herts NHS Trust, Welwyn Garden City, Royal Free Hospital School of Medicine, London, UK
    Diabet Med 19:327-33. 2002
    ..To examine the provision, and variations in, secondary care diabetes services in the UK. METHODOLOGY AND PARTICIPANTS: A postal survey of all 238 identified secondary care providers of diabetes services in 2000...
  49. pmc CD200R1 regulates the severity of arthritis but has minimal impact on the adaptive immune response
    E Simelyte
    Kennedy Institute of Rheumatology, Imperial College London, London, UK
    Clin Exp Immunol 162:163-8. 2010
    ..In contrast, CD200R1 plays a minimal role in shaping the immune response to collagen in this model...
  50. ncbi request reprint Leukotriene and prostaglandin production after infusion of tumour necrosis factor in man
    K P Moore
    Liver Unit, King s College School of Medicine and Dentistry, London, UK
    Eicosanoids 4:115-8. 1991
    ..We conclude that there is increased production of cysteinyl leukotrienes, thromboxane A2 and prostacyclin after infusion of tumour necrosis factor into man...
  51. ncbi request reprint Natural history and prognostic variables in primary sclerosing cholangitis
    J M Farrant
    Department of Radiology, King s College Hospital, Denmark Hill, London, England
    Gastroenterology 100:1710-7. 1991
    ....
  52. ncbi request reprint Increased production of cysteinyl leukotrienes in hepatorenal syndrome
    K P Moore
    Liver Unit, King s College Hospital, Denmark Hill, London, United Kingdom
    J Hepatol 11:263-71. 1990
    ..This may be one of the factors involved in its pathogenesis...
  53. pmc Cellular immunity to nucleocapsid and pre-S determinants in asymptomatic carriers of hepatitis B virus
    S Vento
    Liver Unit, King s College School of Medicine and Dentistry, Denmark Hill, London
    Immunology 62:593-8. 1987
    ..Hence, T-cell immunity to pre-S determinants may not always be associated with HBV clearance...
  54. doi request reprint Association of British Clinical Diabetologists (ABCD) and Diabetes-UK survey of specialist diabetes services in the UK, 2006. 1. The consultant physician perspective
    P H Winocour
    Diabetes UK, London, UK
    Diabet Med 25:643-50. 2008
    ..To identify the views and working practices of consultant diabetologists in the UK in 2006-2007, the current provision of specialist services, and to examine changes since 2000...
  55. ncbi request reprint MUC 1: a genetic susceptibility to infertility?
    A W Horne
    Institute of Reproductive and Developmental Biology, Hammersmith Hospital Campus, Imperial College School of Medicine, W12 0NN, London, UK
    Lancet 357:1336-7. 2001
    ..5 kb compared with 3.4 kb in the fertile group (p=0.0029, difference 0.9, [95% CI 0.1-1.3]). Women with unexplained infertility might have a genetic susceptibility to failure of embryo implantation due to small MUC 1 allele size...
  56. ncbi request reprint Correlating physiology with gene expression in striatal cholinergic neurones
    P J Richardson
    Department of Pharmacology, University of Cambridge, Sanger Centre, England, UK
    J Neurochem 74:839-46. 2000
    ..Subpopulations of these cholinergic neurones have been identified on the basis of the expression of the NK3 tachykinin receptor in 5% and the trkC neurotrophin receptor in 12% of the cells investigated...
  57. ncbi request reprint Screening for distress in cancer patients: is the distress thermometer a valid measure in the UK and does it measure change over time? A prospective validation study
    S Gessler
    UCL Hospitals Gynaecological Oncology Centre, Elizabeth Garrett Anderson Hospital, London, UK
    Psychooncology 17:538-47. 2008
    ..Our results indicate that it can be used to monitor change in psychological distress over time, but further work is needed to confirm this...
  58. pmc Intestinal absorption of mixed micellar phylloquinone (vitamin K1) is unreliable in infants with conjugated hyperbilirubinaemia: implications for oral prophylaxis of vitamin K deficiency bleeding
    S P Pereira
    Department of Gastroenterology, The Middlesex Hospital, University College London Hospitals NHS Trust, London, UK
    Arch Dis Child Fetal Neonatal Ed 88:F113-8. 2003
    ..To compare the pharmacokinetics and efficacy of oral versus intravenous mixed micellar vitamin K prophylaxis in infants with cholestatic liver disease, a known risk factor for vitamin K deficiency bleeding...
  59. pmc Tumour necrosis factor alpha is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis
    R P Mookerjee
    Liver Failure Group, Institute of Hepatology, London, UK
    Gut 52:1182-7. 2003
    ..The role of proinflammatory cytokines in the pathogenesis of portal hypertension is unclear...
  60. ncbi request reprint Introduction: the burden, pathophysiology and management of hepatic encephalopathy
    R Williams
    The UCL Institute of Hepatology, Royal Free and University College Medical School, University College London, UK
    Aliment Pharmacol Ther 25:1-2. 2007
  61. ncbi request reprint Remote ischaemic preconditioning of the hind limb reduces experimental liver warm ischaemia-reperfusion injury
    S Kanoria
    Hepatopancreatobiliary and Liver Transplant Unit, University Department of Surgery, Royal Free Hospital, London, UK
    Br J Surg 93:762-8. 2006
    ..Remote ischaemic preconditioning (RIPC) of a limb has been shown to reduce IRI to the heart. This study determined the effect of brief remote ischaemia to the limb in reducing early liver warm IRI...
  62. ncbi request reprint A controlled trial of ondansetron in the pruritus of cholestasis
    J W O'Donohue
    Institute of Liver Studies, King s College Hospital, London, UK
    Aliment Pharmacol Ther 21:1041-5. 2005
    ..The 5-hydroxytryptamine(3) receptor antagonist, ondansetron, has been used in the treatment of pruritus of cholestasis, but there are few controlled data...
  63. ncbi request reprint Structural airway abnormalities in infants and young children with cystic fibrosis
    Frederick R Long
    Children s Radiological Institute, Children s Hospital, Department of Pediatrics, Ohio State University School of Medicine and Public Health, Children s Hospital and Children s Research Institute, Columbus, Ohio 43205 2696, USA
    J Pediatr 144:154-61. 2004
    ..8+/-1.4 years). Short axis diameters of all clearly identifiable, round airway/vessel pairs were measured to obtain airway wall thickness (AWT), airway lumen diameter (ALD), and vessel diameter (VD)...
  64. ncbi request reprint Inspiratory and expiratory CT lung density in infants and young children
    Frederick R Long
    Children s Radiological Institute, Children s Hospital, 700 Children s Drive, Columbus, OH 43205 2696, USA
    Pediatr Radiol 35:677-83. 2005
    ..There is a lack of information on normal inspiratory and expiratory CT lung density in infants...
  65. ncbi request reprint Comparison of quiet breathing and controlled ventilation in the high-resolution CT assessment of airway disease in infants with cystic fibrosis
    Frederick R Long
    Children s Hospital, Children s Radiological Institute, 700 Children s Drive, Columbus, OH 43205, USA
    Pediatr Radiol 35:1075-80. 2005
    ..Respiratory motion and low lung volumes limit the quality of HRCT examinations in infants and young children...