Dillwyn Williams

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Cancer after nuclear fallout: lessons from the Chernobyl accident
    Dillwyn Williams
    Thyroid Carcinogenesis Research Group, Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
    Nat Rev Cancer 2:543-9. 2002
  2. ncbi request reprint Chernobyl and the future: too soon for a final diagnosis
    Dillwyn Williams
    Thyroid Carcinogenesis Research Group, Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, UK
    Nature 440:993-4. 2006
  3. doi request reprint Twenty years' experience with post-Chernobyl thyroid cancer
    Dillwyn Williams
    Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Best Pract Res Clin Endocrinol Metab 22:1061-73. 2008
  4. pmc Morphologic characteristics of Chernobyl-related childhood papillary thyroid carcinomas are independent of radiation exposure but vary with iodine intake
    E Dillwyn Williams
    Strangeways Research Laboratory, Thyroid Carcinogenesis Research Unit, Worts Causeway, Cambridge, United Kingdom
    Thyroid 18:847-52. 2008
  5. ncbi request reprint Chernobyl and thyroid cancer
    E D Williams
    Strangeways Research Laboratory, Worts Causeway, Cambridge, United Kingdom
    J Surg Oncol 94:670-7. 2006
  6. pmc Thyroid carcinoma after Chernobyl latent period, morphology and aggressiveness
    E D Williams
    Thyroid Carcinogenesis Research Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Br J Cancer 90:2219-24. 2004
  7. ncbi request reprint DNA replication licensing and human cell proliferation
    K Stoeber
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Cell Sci 114:2027-41. 2001
  8. ncbi request reprint A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiency
    S Sanders
    Department of Histopathology, Addenbrooke s Hospital, Cambridge, UK
    Mutat Res 374:79-87. 1997
  9. ncbi request reprint BRAF mutations are not a major event in post-Chernobyl childhood thyroid carcinomas
    Jorge Lima
    Institute of Molecular Pathology and Immunology, University of Porto, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    J Clin Endocrinol Metab 89:4267-71. 2004
  10. ncbi request reprint Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas
    Jorge Lima
    Cancer Lett 230:149-50. 2005

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Cancer after nuclear fallout: lessons from the Chernobyl accident
    Dillwyn Williams
    Thyroid Carcinogenesis Research Group, Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
    Nat Rev Cancer 2:543-9. 2002
  2. ncbi request reprint Chernobyl and the future: too soon for a final diagnosis
    Dillwyn Williams
    Thyroid Carcinogenesis Research Group, Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, UK
    Nature 440:993-4. 2006
  3. doi request reprint Twenty years' experience with post-Chernobyl thyroid cancer
    Dillwyn Williams
    Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Best Pract Res Clin Endocrinol Metab 22:1061-73. 2008
    ..Other factors linked to susceptibility to thyroid carcinogenesis after Chernobyl include dose, iodine deficiency, and genetic factors. Other consequences are briefly covered...
  4. pmc Morphologic characteristics of Chernobyl-related childhood papillary thyroid carcinomas are independent of radiation exposure but vary with iodine intake
    E Dillwyn Williams
    Strangeways Research Laboratory, Thyroid Carcinogenesis Research Unit, Worts Causeway, Cambridge, United Kingdom
    Thyroid 18:847-52. 2008
    ..We have investigated whether unexpected features of the PTC incidence after Chernobyl were radiation specific or influenced by iodine deficiency...
  5. ncbi request reprint Chernobyl and thyroid cancer
    E D Williams
    Strangeways Research Laboratory, Worts Causeway, Cambridge, United Kingdom
    J Surg Oncol 94:670-7. 2006
    ....
  6. pmc Thyroid carcinoma after Chernobyl latent period, morphology and aggressiveness
    E D Williams
    Thyroid Carcinogenesis Research Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
    Br J Cancer 90:2219-24. 2004
    ....
  7. ncbi request reprint DNA replication licensing and human cell proliferation
    K Stoeber
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Cell Sci 114:2027-41. 2001
    ..We conclude that biomarkers for replication-licensed cells detect, in addition to actively proliferating cells, cells with growth potential, a concept that has major implications for developmental and cancer biology...
  8. ncbi request reprint A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiency
    S Sanders
    Department of Histopathology, Addenbrooke s Hospital, Cambridge, UK
    Mutat Res 374:79-87. 1997
    ..We believe that the reduced enzyme activity in the GPDX mouse is due to the mutation in the 5' untranslated region (UTR), and that similar mutations may be relevant in other inherited conditions...
  9. ncbi request reprint BRAF mutations are not a major event in post-Chernobyl childhood thyroid carcinomas
    Jorge Lima
    Institute of Molecular Pathology and Immunology, University of Porto, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    J Clin Endocrinol Metab 89:4267-71. 2004
    ..We conclude that the frequency of BRAF mutations is significantly lower (P = 0.0008) in post-Chernobyl PTC than in adult sporadic PTC, whereas no significant difference was found between post-Chernobyl and sporadic childhood PTCs...
  10. ncbi request reprint Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas
    Jorge Lima
    Cancer Lett 230:149-50. 2005
  11. pmc The chernobyl accident 20 years on: an assessment of the health consequences and the international response
    Keith Baverstock
    Department of Environmental Sciences, Faculty of Natural and Environmental Sciences, University of Kuopio, Kuopio, Finland
    Environ Health Perspect 114:1312-7. 2006
    ..Accurate assessment of the consequences is important to the current debate on nuclear power...
  12. ncbi request reprint Re: Lohrer,H.D., Hieber,L. and Zitzelsberger,H. (2002) Differential mutation frequency in mitochondrial DNA from thyroid tumours. Carcinogenesis, 23, 1577-1582
    Jorge Lima
    Carcinogenesis 24:1155. 2003
  13. ncbi request reprint The Chernobyl accident 20 years on: an assessment of the health consequences and the international response
    Keith Baverstock
    Department of Environmental Sciences, Faculty of Natural and Environmental Sciences, University of Kuopio, Kuopio, 70211, Finland
    Cien Saude Colet 12:689-98. 2007
    ..These should involve independent scientists and ensure cooperation rather than rivalry...
  14. ncbi request reprint Chernobyl: an overlooked aspect?
    Keith Baverstock
    Science 299:44. 2003
  15. ncbi request reprint Risk of thyroid cancer after exposure to 131I in childhood
    Elisabeth Cardis
    International Agency for Research on Cancer, Lyon, France
    J Natl Cancer Inst 97:724-32. 2005
    ....
  16. ncbi request reprint Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia
    Jorge Lima
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto 4200 465, Portugal
    J Clin Endocrinol Metab 88:4932-7. 2003
    ..Our studies suggest that a mutation in SDHD may be causative. These observations have implications for apparently incidental cases of hypercalcitoninemia or C cell hyperplasia...