Affiliation: University of Cambridge
- Cancer after nuclear fallout: lessons from the Chernobyl accidentDillwyn Williams
Thyroid Carcinogenesis Research Group, Strangeways Research Laboratory, Wort's Causeway, Cambridge, CB1 8RN, UK
Nat Rev Cancer 2:543-9. 2002
- Chernobyl and the future: too soon for a final diagnosisDillwyn Williams
Thyroid Carcinogenesis Research Group, Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, UK
Nature 440:993-4. 2006
- Twenty years' experience with post-Chernobyl thyroid cancerDillwyn Williams
Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
Best Pract Res Clin Endocrinol Metab 22:1061-73. 2008..Other factors linked to susceptibility to thyroid carcinogenesis after Chernobyl include dose, iodine deficiency, and genetic factors. Other consequences are briefly covered...
- Morphologic characteristics of Chernobyl-related childhood papillary thyroid carcinomas are independent of radiation exposure but vary with iodine intakeE Dillwyn Williams
Strangeways Research Laboratory, Thyroid Carcinogenesis Research Unit, Worts Causeway, Cambridge, United Kingdom
Thyroid 18:847-52. 2008..We have investigated whether unexpected features of the PTC incidence after Chernobyl were radiation specific or influenced by iodine deficiency...
- Chernobyl and thyroid cancerE D Williams
Strangeways Research Laboratory, Worts Causeway, Cambridge, United Kingdom
J Surg Oncol 94:670-7. 2006....
- Thyroid carcinoma after Chernobyl latent period, morphology and aggressivenessE D Williams
Thyroid Carcinogenesis Research Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
Br J Cancer 90:2219-24. 2004....
- DNA replication licensing and human cell proliferationK Stoeber
Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
J Cell Sci 114:2027-41. 2001..We conclude that biomarkers for replication-licensed cells detect, in addition to actively proliferating cells, cells with growth potential, a concept that has major implications for developmental and cancer biology...
- A glucose-6-phosphate dehydrogenase (G6PD) splice site consensus sequence mutation associated with G6PD enzyme deficiencyS Sanders
Department of Histopathology, Addenbrooke s Hospital, Cambridge, UK
Mutat Res 374:79-87. 1997..We believe that the reduced enzyme activity in the GPDX mouse is due to the mutation in the 5' untranslated region (UTR), and that similar mutations may be relevant in other inherited conditions...
- BRAF mutations are not a major event in post-Chernobyl childhood thyroid carcinomasJorge Lima
Institute of Molecular Pathology and Immunology, University of Porto, Rua Dr. Roberto Frias s/n, 4200-465 Porto, Portugal
J Clin Endocrinol Metab 89:4267-71. 2004..We conclude that the frequency of BRAF mutations is significantly lower (P = 0.0008) in post-Chernobyl PTC than in adult sporadic PTC, whereas no significant difference was found between post-Chernobyl and sporadic childhood PTCs...
- Reply to: Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomasJorge Lima
Cancer Lett 230:149-50. 2005
- The chernobyl accident 20 years on: an assessment of the health consequences and the international responseKeith Baverstock
Department of Environmental Sciences, Faculty of Natural and Environmental Sciences, University of Kuopio, Kuopio, Finland
Environ Health Perspect 114:1312-7. 2006..Accurate assessment of the consequences is important to the current debate on nuclear power...
- Re: Lohrer,H.D., Hieber,L. and Zitzelsberger,H. (2002) Differential mutation frequency in mitochondrial DNA from thyroid tumours. Carcinogenesis, 23, 1577-1582Jorge Lima
Carcinogenesis 24:1155. 2003
- The Chernobyl accident 20 years on: an assessment of the health consequences and the international responseKeith Baverstock
Department of Environmental Sciences, Faculty of Natural and Environmental Sciences, University of Kuopio, Kuopio, 70211, Finland
Cien Saude Colet 12:689-98. 2007..These should involve independent scientists and ensure cooperation rather than rivalry...
- Chernobyl: an overlooked aspect?Keith Baverstock
Science 299:44. 2003
- Risk of thyroid cancer after exposure to 131I in childhoodElisabeth Cardis
International Agency for Research on Cancer, Lyon, France
J Natl Cancer Inst 97:724-32. 2005....
- Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasiaJorge Lima
Institute of Molecular Pathology and Immunology of the University of Porto, Porto 4200-465, Portugal
J Clin Endocrinol Metab 88:4932-7. 2003..Our studies suggest that a mutation in SDHD may be causative. These observations have implications for apparently incidental cases of hypercalcitoninemia or C cell hyperplasia...