Bryan Williams

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Targets and self-management for the control of blood pressure in stroke and at risk groups (TASMIN-SR): protocol for a randomised controlled trial
    Claire O'Brien
    Primary Care Clinical Sciences, NIHR School for Primary Care Research, University of Birmingham, Edgbaston, Birmingham, UK
    BMC Cardiovasc Disord 13:21. 2013
  2. doi request reprint Novel description of the 24-hour circadian rhythms of brachial versus central aortic blood pressure and the impact of blood pressure treatment in a randomized controlled clinical trial: The Ambulatory Central Aortic Pressure (AmCAP) Study
    Bryan Williams
    Institute of Cardiovascular Science, University College London, 170 Tottenham Court Rd, London W1T 7HA, UK
    Hypertension 61:1168-76. 2013
  3. ncbi request reprint Blood pressure and plasma renin activity responses to different strategies to inhibit the renin-angiotensin-aldosterone system during exercise
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, UK
    J Renin Angiotensin Aldosterone Syst 14:56-66. 2013
  4. doi request reprint Impact of statin therapy on central aortic pressures and hemodynamics: principal results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK
    Circulation 119:53-61. 2009
  5. doi request reprint Impact of heart rate on central aortic pressures and hemodynamics: analysis from the CAFE (Conduit Artery Function Evaluation) study: CAFE-Heart Rate
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, and the Leicester NIHR Cardiovascular Biomedical Research Unit, Leicester, UK
    J Am Coll Cardiol 54:705-13. 2009
  6. ncbi request reprint The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I)
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, Leicester, UK
    J Hypertens 24:193-200. 2006
  7. doi request reprint Development and validation of a novel method to derive central aortic systolic pressure from the radial pressure waveform using an n-point moving average method
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, and the Leicester NIHR Biomedical Research Unit in Cardiovascular Diseases, Leicester, United Kingdom
    J Am Coll Cardiol 57:951-61. 2011
  8. ncbi request reprint Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Circulation 113:1213-25. 2006
  9. doi request reprint The changing face of hypertension treatment: treatment strategies from the 2007 ESH/ESC hypertension Guidelines
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, Leicester, UK
    J Hypertens Suppl 27:S19-26. 2009
  10. doi request reprint Conduit vessel stiffness in British south Asians of Indian descent relates to 25-hydroxyvitamin D status
    David R Webb
    Department of Cardiovascular Sciences, Leicester Royal Infirmary University of Leicester, Leicester, Bedfordshire, UK
    J Hypertens 30:1588-96. 2012

Collaborators

Detail Information

Publications20

  1. pmc Targets and self-management for the control of blood pressure in stroke and at risk groups (TASMIN-SR): protocol for a randomised controlled trial
    Claire O'Brien
    Primary Care Clinical Sciences, NIHR School for Primary Care Research, University of Birmingham, Edgbaston, Birmingham, UK
    BMC Cardiovasc Disord 13:21. 2013
    ..This trial therefore aims to assess the added value of self-management in high risk groups over and above usual care...
  2. doi request reprint Novel description of the 24-hour circadian rhythms of brachial versus central aortic blood pressure and the impact of blood pressure treatment in a randomized controlled clinical trial: The Ambulatory Central Aortic Pressure (AmCAP) Study
    Bryan Williams
    Institute of Cardiovascular Science, University College London, 170 Tottenham Court Rd, London W1T 7HA, UK
    Hypertension 61:1168-76. 2013
    ..These novel data indicate that night-time central BP may provide prognostic importance and warrants further investigation. Clinical Trial Registration- URL: http://www.clinicaltrials.gov. Unique identifier: NCT00865020...
  3. ncbi request reprint Blood pressure and plasma renin activity responses to different strategies to inhibit the renin-angiotensin-aldosterone system during exercise
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, UK
    J Renin Angiotensin Aldosterone Syst 14:56-66. 2013
    ....
  4. doi request reprint Impact of statin therapy on central aortic pressures and hemodynamics: principal results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK
    Circulation 119:53-61. 2009
    ....
  5. doi request reprint Impact of heart rate on central aortic pressures and hemodynamics: analysis from the CAFE (Conduit Artery Function Evaluation) study: CAFE-Heart Rate
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, and the Leicester NIHR Cardiovascular Biomedical Research Unit, Leicester, UK
    J Am Coll Cardiol 54:705-13. 2009
    ..The present study examined the importance of heart rate (HR) as a determinant of this effect...
  6. ncbi request reprint The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I)
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, Leicester, UK
    J Hypertens 24:193-200. 2006
    ..To compare the efficacy and safety of once-daily telmisartan and ramipril on blood pressure (BP) reductions during the last 6 h of the dosing interval...
  7. doi request reprint Development and validation of a novel method to derive central aortic systolic pressure from the radial pressure waveform using an n-point moving average method
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, and the Leicester NIHR Biomedical Research Unit in Cardiovascular Diseases, Leicester, United Kingdom
    J Am Coll Cardiol 57:951-61. 2011
    ....
  8. ncbi request reprint Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Circulation 113:1213-25. 2006
    ....
  9. doi request reprint The changing face of hypertension treatment: treatment strategies from the 2007 ESH/ESC hypertension Guidelines
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, Leicester, UK
    J Hypertens Suppl 27:S19-26. 2009
    ....
  10. doi request reprint Conduit vessel stiffness in British south Asians of Indian descent relates to 25-hydroxyvitamin D status
    David R Webb
    Department of Cardiovascular Sciences, Leicester Royal Infirmary University of Leicester, Leicester, Bedfordshire, UK
    J Hypertens 30:1588-96. 2012
    ..Vitamin D deficiency is common in this group and may play an important role mediating vascular wall senescence in response to central pressure effects...
  11. ncbi request reprint Blood pressure and outcomes in clinical trials
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, Leicester Royal Infirmary, Leicester, UK
    J Hypertens 23:487-8. 2005
  12. doi request reprint Systolic pressure is all that matters
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Lancet 371:2219-21. 2008
  13. ncbi request reprint Protection against stroke and dementia: an update on the latest clinical trial evidence
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, PO Box 65, Leicester Royal Infirmary, Leicester, LE2 7LX, UK
    Curr Hypertens Rep 6:307-13. 2004
    ..Ultimately, however, all agree that for patients with the highest risk for cardiovascular and cerebrovascular complications, the strategy of intervention is immaterial, and drug therapy, including low-dose aspirin, is vital...
  14. ncbi request reprint Increased pulse wave velocity is not associated with elevated augmentation index in patients with diabetes
    Peter S Lacy
    Department of Cardiovascular Sciences, Cardiovascular Research Institute, University of Leicester, Leicester LE2 7LX, UK
    J Hypertens 22:1937-44. 2004
    ..This study compares the relationship between PWV and AI in people with and without diabetes...
  15. pmc Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways
    Karl E Herbert
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Circ Res 102:201-8. 2008
    ....
  16. ncbi request reprint High rates of non-adherence to antihypertensive treatment revealed by high-performance liquid chromatography-tandem mass spectrometry (HP LC-MS/MS) urine analysis
    Maciej Tomaszewski
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Heart 100:855-61. 2014
    ..We used a simple urine-based assay to evaluate the prevalence of antihypertensive treatment non-adherence and its impact on blood pressure in a specialist hypertension centre...
  17. pmc A novel foundation-year-two post in academic medicine
    Adrian G Stanley
    Department of Cardiovascular Sciences, University of Leicester, Robert Kilpatrick Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    J R Soc Med 98:10-3. 2005
  18. ncbi request reprint Rapid telomere attrition in cardiac tissue of the ageing Wistar rat
    Richard Hastings
    Department of Cardiovascular Sciences, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Exp Gerontol 39:855-7. 2004
    ..Moreover, we show differential rates of telomere attrition in rat tissues, the heart being most susceptible to telomere loss. These observations could have important implications for the study of age-specific changes in tissue function...
  19. pmc British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester
    BMJ 328:634-40. 2004