Penny Whiting

Summary

Affiliation: University of York
Country: UK

Publications

  1. ncbi request reprint Sources of variation and bias in studies of diagnostic accuracy: a systematic review
    Penny Whiting
    University of York, York, United Kingdom
    Ann Intern Med 140:189-202. 2004
  2. ncbi request reprint Interventions for the treatment and management of chronic fatigue syndrome: a systematic review
    P Whiting
    National Health Service Centre for Reviews and Dissemination, University of York, York, England, YO10 5DD
    JAMA 286:1360-8. 2001
  3. pmc Association of Down's syndrome and water fluoride level: a systematic review of the evidence
    P Whiting
    NHS Centre for Reviews and Dissemination, University of York, York, Y010 5DD, England
    BMC Public Health 1:6. 2001
  4. pmc The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
    Penny Whiting
    Centre for Reviews and Dissemination, University of York, England, UK
    BMC Med Res Methodol 3:25. 2003
  5. pmc Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis
    Penny Whiting
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 19:1-228, v-vi. 2015
  6. pmc High-sensitivity troponin assays for the early rule-out or diagnosis of acute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 19:1-234. 2015
  7. pmc Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 19:v-xxv, 1-236. 2015
  8. pmc KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 18:1-132. 2014
  9. ncbi request reprint A systematic review finds that diagnostic reviews fail to incorporate quality despite available tools
    Penny Whiting
    Centre for Reviews and Dissemination, University of York, United Kingdom
    J Clin Epidemiol 58:1-12. 2005
  10. doi request reprint Applicability of diagnostic studies--statistics, bias and estimates of diagnostic accuracy
    Jos Kleijnen
    Kleijnen Systematic Reviews Ltd, York, UK
    Z Evid Fortbild Qual Gesundhwes 105:498-503. 2011

Collaborators

  • Jos Kleijnen
  • A M Bagnall
  • Afina S Glas
  • Marie Westwood
  • Johan Severens
  • Nigel Armstrong
  • Bram Ramaekers
  • Manuela Joore
  • Thea van Asselt
  • Janine Ross
  • Praveen Thokala
  • Florian Tomini
  • Steve Ryder
  • Lisa Stirk
  • Kate Misso
  • Caro Noake

Detail Information

Publications13

  1. ncbi request reprint Sources of variation and bias in studies of diagnostic accuracy: a systematic review
    Penny Whiting
    University of York, York, United Kingdom
    Ann Intern Med 140:189-202. 2004
    ..Studies of diagnostic accuracy are subject to different sources of bias and variation than studies that evaluate the effectiveness of an intervention. Little is known about the effects of these sources of bias and variation...
  2. ncbi request reprint Interventions for the treatment and management of chronic fatigue syndrome: a systematic review
    P Whiting
    National Health Service Centre for Reviews and Dissemination, University of York, York, England, YO10 5DD
    JAMA 286:1360-8. 2001
    ..A variety of interventions have been used in the treatment and management of chronic fatigue syndrome (CFS). Currently, debate exists among health care professionals and patients about appropriate strategies for management...
  3. pmc Association of Down's syndrome and water fluoride level: a systematic review of the evidence
    P Whiting
    NHS Centre for Reviews and Dissemination, University of York, York, Y010 5DD, England
    BMC Public Health 1:6. 2001
    ..Only two of the studies controlled for confounding factors and only one of these presented summary outcome measures. CONCLUSIONS: The evidence of an association between water fluoride level and Down's syndrome incidence is inconclusive...
  4. pmc The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
    Penny Whiting
    Centre for Reviews and Dissemination, University of York, England, UK
    BMC Med Res Methodol 3:25. 2003
    ..The aim of this project was to combine empirical evidence and expert opinion in a formal consensus method to develop a tool to be used in systematic reviews to assess the quality of primary studies of diagnostic accuracy...
  5. pmc Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis
    Penny Whiting
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 19:1-228, v-vi. 2015
    ....
  6. pmc High-sensitivity troponin assays for the early rule-out or diagnosis of acute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 19:1-234. 2015
    ..High-sensitivity cardiac troponin (hs-cTn) assays may allow rapid rule-out of AMI and avoidance of unnecessary hospital admissions and anxiety...
  7. pmc Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 19:v-xxv, 1-236. 2015
    ..Procalcitonin (PCT) is an inflammatory marker that has been suggested as a marker for bacterial infection...
  8. pmc KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 18:1-132. 2014
    ..These vary in the specific mutations that they detect, the amount of mutation they detect, the amount of tumour cells needed, the time to give a result, the error rate and cost...
  9. ncbi request reprint A systematic review finds that diagnostic reviews fail to incorporate quality despite available tools
    Penny Whiting
    Centre for Reviews and Dissemination, University of York, United Kingdom
    J Clin Epidemiol 58:1-12. 2005
    ..To review existing quality assessment tools for diagnostic accuracy studies and to examine to what extent quality was assessed and incorporated in diagnostic systematic reviews...
  10. doi request reprint Applicability of diagnostic studies--statistics, bias and estimates of diagnostic accuracy
    Jos Kleijnen
    Kleijnen Systematic Reviews Ltd, York, UK
    Z Evid Fortbild Qual Gesundhwes 105:498-503. 2011
    ..Simple as they may seem, these points cover extremely complex issues in practice, and these need to be addressed by more communication between methodologists, practitioners and decision makers...
  11. pmc Epidermal growth factor receptor tyrosine kinase (EGFR-TK) mutation testing in adults with locally advanced or metastatic non-small cell lung cancer: a systematic review and cost-effectiveness analysis
    Marie Westwood
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 18:1-166. 2014
    ..The different tests vary in the specific mutations that they attempt to detect, the amount of tumour cells needed for the test to work, the time that it takes to give a result, the error rate of the test, and the cost of the test...
  12. pmc Ivacaftor for the treatment of patients with cystic fibrosis and the G551D mutation: a systematic review and cost-effectiveness analysis
    Penny Whiting
    Kleijnen Systematic Reviews Ltd, York, UK
    Health Technol Assess 18:1-106. 2014
    ..It is aimed at patients with the G551D (glycine to aspartate change in nucleotide 1784 in exon 11) mutation; 5.7% of patients with CF in the UK have this mutation...
  13. pmc Rapid tests and urine sampling techniques for the diagnosis of urinary tract infection (UTI) in children under five years: a systematic review
    Penny Whiting
    MRC Health Services Research Collaboration, University of Bristol, England, UK
    BMC Pediatr 5:4. 2005
    ..Prompt diagnosis and treatment is important to reduce the risk of renal scarring. Rapid, cost-effective, methods of UTI diagnosis are required as an alternative to culture...