Penny F Whiting

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Is MRI better than CT for detecting a vascular component to dementia? A systematic review and meta-analysis
    Rebecca Beynon
    School of Social and Community Medicine, University of Bristol, Canynge Hall, Bristol, BS8 2PS, UK
    BMC Neurol 12:33. 2012
  2. doi request reprint Systematic review: accuracy of anti-citrullinated Peptide antibodies for diagnosing rheumatoid arthritis
    Penny F Whiting
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, United Kingdom
    Ann Intern Med 152:456-64; W155-66. 2010
  3. doi request reprint Evidence-based diagnosis
    Penny Whiting
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Health Serv Res Policy 13:57-63. 2008
  4. pmc Graphical presentation of diagnostic information
    Penny F Whiting
    Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    BMC Med Res Methodol 8:20. 2008
  5. doi request reprint Inclusion of methodological filters in searches for diagnostic test accuracy studies misses relevant studies
    Penny Whiting
    School of Social and Community Medicine, University of Bristol, Bristol BS8 2PR, UK
    J Clin Epidemiol 64:602-7. 2011
  6. doi request reprint QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies
    Penny F Whiting
    University of Bristol, United Kingdom
    Ann Intern Med 155:529-36. 2011
  7. pmc Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic review
    Penny Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, Bristol BS8 2PR
    BMJ 332:875-84. 2006
  8. pmc Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies
    Penny F Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, UK
    BMC Med Res Methodol 6:9. 2006
  9. pmc No role for quality scores in systematic reviews of diagnostic accuracy studies
    Penny Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Bristol, UK
    BMC Med Res Methodol 5:19. 2005
  10. pmc Rapid tests and urine sampling techniques for the diagnosis of urinary tract infection (UTI) in children under five years: a systematic review
    Penny Whiting
    MRC Health Services Research Collaboration, University of Bristol, England, UK
    BMC Pediatr 5:4. 2005

Detail Information

Publications20

  1. pmc Is MRI better than CT for detecting a vascular component to dementia? A systematic review and meta-analysis
    Rebecca Beynon
    School of Social and Community Medicine, University of Bristol, Canynge Hall, Bristol, BS8 2PS, UK
    BMC Neurol 12:33. 2012
    ..We conducted a systematic review and meta-analysis to investigate this question...
  2. doi request reprint Systematic review: accuracy of anti-citrullinated Peptide antibodies for diagnosing rheumatoid arthritis
    Penny F Whiting
    Department of Social Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, United Kingdom
    Ann Intern Med 152:456-64; W155-66. 2010
    ..Early recognition and treatment of rheumatoid arthritis is important to prevent irreversible joint damage. Anti-citrullinated peptide antibodies (ACPA) have been suggested for early diagnosis...
  3. doi request reprint Evidence-based diagnosis
    Penny Whiting
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Health Serv Res Policy 13:57-63. 2008
    ..Three areas that would benefit from further research are literature searching, synthesis of results from individual patient data and presentation of results...
  4. pmc Graphical presentation of diagnostic information
    Penny F Whiting
    Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    BMC Med Res Methodol 8:20. 2008
    ..Diagnostic information should be presented in an easily interpretable way, which conveys both test characteristics (diagnostic accuracy) and the potential for use in clinical practice (predictive value)...
  5. doi request reprint Inclusion of methodological filters in searches for diagnostic test accuracy studies misses relevant studies
    Penny Whiting
    School of Social and Community Medicine, University of Bristol, Bristol BS8 2PR, UK
    J Clin Epidemiol 64:602-7. 2011
    ..To compare the performance of MEDLINE searches using index test(s) and target condition (subject searches) with the same searches combined with methodological filters for test accuracy studies...
  6. doi request reprint QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies
    Penny F Whiting
    University of Bristol, United Kingdom
    Ann Intern Med 155:529-36. 2011
    ..This tool will allow for more transparent rating of bias and applicability of primary diagnostic accuracy studies...
  7. pmc Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic review
    Penny Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, Bristol BS8 2PR
    BMJ 332:875-84. 2006
    ..To determine the accuracy of magnetic resonance imaging criteria for the early diagnosis of multiple sclerosis in patients with suspected disease...
  8. pmc Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies
    Penny F Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, UK
    BMC Med Res Methodol 6:9. 2006
    ..Although QUADAS has been used in several systematic reviews, it has not been formally validated. The objective was to evaluate the validity and usefulness of QUADAS...
  9. pmc No role for quality scores in systematic reviews of diagnostic accuracy studies
    Penny Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Bristol, UK
    BMC Med Res Methodol 5:19. 2005
    ....
  10. pmc Rapid tests and urine sampling techniques for the diagnosis of urinary tract infection (UTI) in children under five years: a systematic review
    Penny Whiting
    MRC Health Services Research Collaboration, University of Bristol, England, UK
    BMC Pediatr 5:4. 2005
    ..Prompt diagnosis and treatment is important to reduce the risk of renal scarring. Rapid, cost-effective, methods of UTI diagnosis are required as an alternative to culture...
  11. ncbi request reprint A systematic review finds that diagnostic reviews fail to incorporate quality despite available tools
    Penny Whiting
    Centre for Reviews and Dissemination, University of York, United Kingdom
    J Clin Epidemiol 58:1-12. 2005
    ..To review existing quality assessment tools for diagnostic accuracy studies and to examine to what extent quality was assessed and incorporated in diagnostic systematic reviews...
  12. pmc How does study quality affect the results of a diagnostic meta-analysis?
    Marie E Westwood
    Centre for Reviews and Dissemination, University of York, UK
    BMC Med Res Methodol 5:20. 2005
    ..A secondary objective was to contribute to the evaluation of QUADAS, an evidence-based tool for the assessment of quality in diagnostic accuracy studies...
  13. pmc Further investigation of confirmed urinary tract infection (UTI) in children under five years: a systematic review
    Marie E Westwood
    Centre for Reviews and Dissemination, University of York, England
    BMC Pediatr 5:2. 2005
    ..Further investigation of confirmed UTI in children aims to prevent renal scarring and future complications...
  14. ncbi request reprint A unification of models for meta-analysis of diagnostic accuracy studies
    Roger M Harbord
    Medical Research Council Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
    Biostatistics 8:239-51. 2007
    ..We discuss the different forms of summary model output suggested by the two approaches, including summary ROC curves, summary points, confidence regions, and prediction regions...
  15. doi request reprint An empirical comparison of methods for meta-analysis of diagnostic accuracy showed hierarchical models are necessary
    Roger M Harbord
    MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Bristol, UK
    J Clin Epidemiol 61:1095-103. 2008
    ..Statistically rigorous hierarchical models require expertise and sophisticated software. We assessed whether any of the simpler methods can in practice give adequately accurate and reliable results...
  16. doi request reprint A systematic review classifies sources of bias and variation in diagnostic test accuracy studies
    Penny F Whiting
    Kleijnen Systematic Reviews Ltd, Unit 6, Escrick Business Park, Riccall Road, Escrick, York YO19 6FD, United Kingdom
    J Clin Epidemiol 66:1093-104. 2013
    ..To classify the sources of bias and variation and to provide an updated summary of the evidence of the effects of each source of bias and variation...
  17. pmc The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
    Penny Whiting
    Centre for Reviews and Dissemination, University of York, England, UK
    BMC Med Res Methodol 3:25. 2003
    ..The aim of this project was to combine empirical evidence and expert opinion in a formal consensus method to develop a tool to be used in systematic reviews to assess the quality of primary studies of diagnostic accuracy...
  18. doi request reprint Systematic reviews of test accuracy should search a range of databases to identify primary studies
    Penny Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    J Clin Epidemiol 61:357-364. 2008
    ..To estimate the yield from searching a range of bibliographic databases and additional sources to identify test accuracy studies for systematic reviews...
  19. ncbi request reprint A review identifies and classifies reasons for ordering diagnostic tests
    Penny Whiting
    MRC Health Services Research Collaboration, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Clin Epidemiol 60:981-9. 2007
    ..To consider the reasons and context for test ordering by doctors when faced with an undiagnosed complaint in primary or secondary care...
  20. ncbi request reprint Sources of variation and bias in studies of diagnostic accuracy: a systematic review
    Penny Whiting
    University of York, York, United Kingdom
    Ann Intern Med 140:189-202. 2004
    ..Studies of diagnostic accuracy are subject to different sources of bias and variation than studies that evaluate the effectiveness of an intervention. Little is known about the effects of these sources of bias and variation...