William Whiteley

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials
    William N Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Bramwell Dott Building, Western General Hospital, Edinburgh, UK
    Lancet Neurol 12:539-45. 2013
  2. doi request reprint Risk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator: a systematic review and meta-analysis of 55 studies
    William N Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU
    Stroke 43:2904-9. 2012
  3. doi request reprint Blood biomarkers in stroke: research and clinical practice
    William Whiteley
    Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Int J Stroke 7:435-9. 2012
  4. pmc Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
    Peter Sandercock
    The IST 3 Co ordinating Centre, Neurosciences Trial Unit, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Trials 12:252. 2011
  5. doi request reprint The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke
    William Whiteley
    Division of Clinical Neurosciences, General Hospital, University of Edinburgh, Edinburgh, UK
    Stroke 43:86-91. 2012
  6. doi request reprint Identifying blood biomarkers to improve the diagnosis of stroke
    W Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    J R Coll Physicians Edinb 41:152-4. 2011
  7. doi request reprint Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: a cross-sectional study
    William N Whiteley
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 82:1006-10. 2011
  8. pmc Association of circulating inflammatory markers with recurrent vascular events after stroke: a prospective cohort study
    William Whiteley
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK
    Stroke 42:10-6. 2011
  9. pmc Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6
    William Whiteley
    Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 6:e1000145. 2009
  10. doi request reprint Blood markers for the prognosis of ischemic stroke: a systematic review
    William Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Stroke 40:e380-9. 2009

Detail Information

Publications15

  1. pmc Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials
    William N Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Bramwell Dott Building, Western General Hospital, Edinburgh, UK
    Lancet Neurol 12:539-45. 2013
    ..We sought to identify reliable methods to target anticoagulant treatment and so improve the chance of avoiding death or dependence after stroke...
  2. doi request reprint Risk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator: a systematic review and meta-analysis of 55 studies
    William N Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU
    Stroke 43:2904-9. 2012
    ..We sought to identify the risk factors for ICH with a systematic review of the published literature...
  3. doi request reprint Blood biomarkers in stroke: research and clinical practice
    William Whiteley
    Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Int J Stroke 7:435-9. 2012
    ..We review the approaches to the development of a diagnostic blood marker: a candidate marker approach, marker panels, and -omics. Then we examined the role of blood markers to predict recurrent stroke and treatment response in stroke...
  4. pmc Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
    Peter Sandercock
    The IST 3 Co ordinating Centre, Neurosciences Trial Unit, Bramwell Dott Building, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    Trials 12:252. 2011
    ..IST-3 sought to improve the external validity and precision of the estimates of the overall treatment effects (efficacy and safety) of rtPA in acute ischaemic stroke, and to determine whether a wider range of patients might benefit...
  5. doi request reprint The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke
    William Whiteley
    Division of Clinical Neurosciences, General Hospital, University of Edinburgh, Edinburgh, UK
    Stroke 43:86-91. 2012
    ..We investigated whether such measurements improved the classification of patients into 4 categories of predicted risk of poor outcome: very high, intermediate high, intermediate low, and very low...
  6. doi request reprint Identifying blood biomarkers to improve the diagnosis of stroke
    W Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    J R Coll Physicians Edinb 41:152-4. 2011
    ....
  7. doi request reprint Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: a cross-sectional study
    William N Whiteley
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, UK
    J Neurol Neurosurg Psychiatry 82:1006-10. 2011
    ..To compare the sensitivity and specificity of bedside diagnostic stroke scales in patients with suspected stroke...
  8. pmc Association of circulating inflammatory markers with recurrent vascular events after stroke: a prospective cohort study
    William Whiteley
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK
    Stroke 42:10-6. 2011
    ....
  9. pmc Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6
    William Whiteley
    Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 6:e1000145. 2009
    ....
  10. doi request reprint Blood markers for the prognosis of ischemic stroke: a systematic review
    William Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Stroke 40:e380-9. 2009
    ..The performance of validated prognostic clinical models in acute ischemic stroke might be improved by addition of data on blood biomarkers...
  11. doi request reprint Blood biomarkers in the diagnosis of ischemic stroke: a systematic review
    William Whiteley
    Division of Clinical Neurosciences, University of Edinburgh, UK
    Stroke 39:2902-9. 2008
    ..CT may be normal in the early stages of ischemic stroke or in patients with minor symptoms and MR is not always possible. Many blood markers have been proposed for the diagnosis of stroke in the acute setting...
  12. ncbi request reprint Fridtjof Nansen (1861-1930)
    William Whiteley
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK
    J Neurol 253:1653-4. 2006
  13. doi request reprint Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study
    William Whiteley
    Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Crewe Road, Edinburgh, UK william whiteley ed ac uk
    Cerebrovasc Dis 32:141-7. 2011
    ..The diagnosis of stroke or TIA in the emergency department is difficult, though important for early treatment. Circulating biomarkers might improve upon clinical assessment at admission...
  14. doi request reprint Hoover's sign for the diagnosis of functional weakness: a prospective unblinded cohort study in patients with suspected stroke
    Laura McWhirter
    Division of Clinical Neurosciences, Bramwell Dott Building, Western General Hospital, Edinburgh EH4 2XU, United Kingdom
    J Psychosom Res 71:384-6. 2011
    ..However, little is known about the performance of this sign in clinical practice...
  15. doi request reprint Third international stroke trial
    William Whiteley
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
    Int J Stroke 1:172-6. 2006