- Tumor necrosis factor alpha can contribute to focal loss of cartilage in osteoarthritisC I Westacott
Department of Pathology and Microbiology, University of Bristol, Bristol, U K
Osteoarthritis Cartilage 8:213-21. 2000..OBJECTIVE; To evaluate the potential for tumor necrosis factor alpha (TNFalpha)-induced focal loss of cartilage in osteoarthritic (OA) knee joints...
- The effects of pressure on chondrocyte tumour necrosis factor receptor expressionC I Westacott
Department of Pathology, University of Bristol Medical School, Bristol BS8 1TD, UK
Biorheology 39:125-32. 2002..These results suggest a mechanism whereby sensitivity of chondrocytes to the effects of TNFalpha may be increased, in susceptible individuals, in regions of the joint that experience peak loading...
- Susceptibility to physiological concentrations of IL-1beta varies in cartilage at different anatomical locations on human osteoarthritic knee jointsA F Barakat
University of Mansoura Medical School, Mansoura, Egypt
Osteoarthritis Cartilage 10:264-9. 2002..To establish whether biopsies are sensitive to the effects of either IL-1 beta or TNFalpha or both catabolic cytokines...