Research Topics
| Ailsa WelchSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
Blood pressure and urinary sodium in men and women: the Norfolk Cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk)Kay Tee Khaw
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom
Am J Clin Nutr 80:1397-403. 2004..A key issue is whether differences in usual sodium intake within the range feasible in free-living populations have clinical or public health relevance...- Body fat distribution and risk of coronary heart disease in men and women in the European Prospective Investigation Into Cancer and Nutrition in Norfolk cohort: a population-based prospective studyDexter Canoy
Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
Circulation 116:2933-43. 2007..Body fat distribution has been cross-sectionally associated with atherosclerotic disease risk factors, but the prospective relation with coronary heart disease remains uncertain... - DINER (Data Into Nutrients for Epidemiological Research) - a new data-entry program for nutritional analysis in the EPIC-Norfolk cohort and the 7-day diary methodA A Welch
University of Cambridge, Institute of Public Health, Wort s Causeway, UK
Public Health Nutr 4:1253-65. 2001..The system has been designed to be fully flexible and easy to update. Analysis of consistency of data entry was tested in a group of 3525 participants entered by 25 coders... - Variability of fish consumption within the 10 European countries participating in the European Investigation into Cancer and Nutrition (EPIC) studyA A Welch
Strangeways Research Laboratory, Department of Public Health and Primary Care, University of Cambridge, Wort s Causeway, UK
Public Health Nutr 5:1273-85. 2002.... - Broadband ultrasound attenuation (BUA) of the heel bone and its correlates in men and women in the EPIC-Norfolk cohort: a cross-sectional population-based studyAilsa Welch
Department of Public Health and Primary Care, University of Cambridge, CB1 8RN, Cambridge, UK
Osteoporos Int 15:217-25. 2004..A better understanding of these determinants of heel ultrasound may provide insights into how some of the sex differences in bone health can be explained and bone loss in later life minimised... 
Combined impact of health behaviours and mortality in men and women: the EPIC-Norfolk prospective population studyKay Tee Khaw
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom
PLoS Med 5:e12. 2008..We aimed to quantify the potential combined impact of four health behaviours on mortality in men and women living in the general community...- Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal womenMei Fen Chan
Department of Public Health and Primary Care, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom
Menopause 15:332-9. 2008..The aim of this study was to examine the relationship between past hormone use and current endogenous hormone status... - Fibrinogen and cigarette smoking in men and women in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) populationShubhada Sinha
Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
Eur J Cardiovasc Prev Rehabil 12:144-50. 2005..In men who stop smoking plasma fibrinogen may remain elevated for several years after cessation... - Prediction of total and hip fracture risk in men and women by quantitative ultrasound of the calcaneus: EPIC-Norfolk prospective population studyKay Tee Khaw
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK
Lancet 363:197-202. 2004..We aimed to assess quantitative ultrasound of the calcaneum and fracture incidence in a prospective observational population study... - Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort studyDexter Canoy
Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
Am J Clin Nutr 82:1203-9. 2005..Excess fat may promote fatty acid oxidation and increase free radical concentrations, which could result in increased antioxidant use. Whether plasma ascorbic acid concentrations are associated with fat distribution remains unclear... - Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The European Prospective Investigation into Cancer in Norfolk prospective popKay Tee Khaw
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, UK
Int J Epidemiol 35:1034-43. 2006..This may be partly related to different methods for assessing physical activity. Most studies have focused on leisure time physical activity... - Fat distribution, body mass index and blood pressure in 22,090 men and women in the Norfolk cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) studyDexter Canoy
Department of Public Health and Primary Care, University of Cambridge, Cambridge, MRC Dunn Human Nutrition Unit, Cambridge and MRC Epidemiology Unit, Cambridge, UK
J Hypertens 22:2067-74. 2004..To determine the relation between fat distribution and blood pressure, independent of body mass index... - Cigarette smoking and fat distribution in 21,828 British men and women: a population-based studyDexter Canoy
Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK
Obes Res 13:1466-75. 2005..To examine the relationship between cigarette smoking habits and fat distribution in a population-based cohort of men and women... 
Associations between dietary methods and biomarkers, and between fruits and vegetables and risk of ischaemic heart disease, in the EPIC Norfolk Cohort StudySheila Bingham
Medical Research Council, Dunn Human Nutrition Unit, Welcome Trust MRC Building, Cambridge, UK
Int J Epidemiol 37:978-87. 2008..Methods for assessing diet are prone to measurement error, which may be substantial in large cohort investigations. Biomarkers can be used as objective measures with which to compare estimates of nutritional exposure using different methods..- Microalbuminuria, cardiovascular risk factors and cardiovascular morbidity in a British population: the EPIC-Norfolk population-based studyMatthew F Yuyun
Department of Public Health and Primary Care, Institute of Public Health, School of Clinical Medicine, University of Cambridge, Robinson Way, Cambridge CB2 2SR, UK
Eur J Cardiovasc Prev Rehabil 11:207-13. 2004..Microalbuminuria may be a useful indicator of high absolute cardiovascular risk in the community but prospective data are needed to establish its independent predictive value for future events... - Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in NorfolkKay Tee Khaw
University of Cambridge, School of Clinical Medicine, Medical Research Council Epidemiology Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
Ann Intern Med 141:413-20. 2004..Increasing evidence suggests a continuous relationship between blood glucose concentrations and cardiovascular risk, even below diagnostic threshold levels for diabetes... - Self-reported parkinsonian symptoms in the EPIC-Norfolk cohortLianna S Ishihara
Department of Public Health and Primary Care, University of Cambridge, Forvie Site, Cambridge CB2 2SR, UK
BMC Neurol 5:15. 2005..The objective of the study was to determine the self-reported prevalence of parkinsonian symptoms from a questionnaire, and to examine their association with age and self-reported Parkinson's disease in a large cohort... - Preliminary communication: glycated hemoglobin, diabetes, and incident colorectal cancer in men and women: a prospective analysis from the European prospective investigation into cancer-Norfolk studyKay Tee Khaw
Depqartment of Public Health and Primary Care, Institute of Public Health, University of Cambridge, United Kingdom
Cancer Epidemiol Biomarkers Prev 13:915-9. 2004..Increasing evidence suggests that abnormal glucose metabolism may be associated with increased risk of colorectal cancer... - Serum lipid concentration in relation to anthropometric indices of central and peripheral fat distribution in 20,021 British men and women: results from the EPIC-Norfolk population-based cohort studyDexter Canoy
Department of Public Health and Primary Care, University of Cambridge, Strangeway s Site, Worts Causeway, Cambridge CB1 8RN, United Kingdom
Atherosclerosis 189:420-7. 2006..We examine whether lipid levels vary between central and peripheral fat distribution in the general population... - Microalbuminuria independently predicts all-cause and cardiovascular mortality in a British population: The European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population studyMatthew F Yuyun
Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, UK
Int J Epidemiol 33:189-98. 2004.... - Usual physical activity and endogenous sex hormones in postmenopausal women: the European prospective investigation into cancer-norfolk population studyMei Fen Chan
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom
Cancer Epidemiol Biomarkers Prev 16:900-5. 2007..However, the relationship between usual daily physical activity and endogenous hormones in postmenopausal women in the general population is still uncertain... - Calcaneum broadband ultrasound attenuation relates to vegetarian and omnivorous diets differently in men and women: an observation from the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population studyAilsa Welch
Department of Public Health and Primary Care, Strangeway s Research Laboratory, University of Cambridge, Cambridge, CB1 8RN, UK
Osteoporos Int 16:590-6. 2005..Our findings emphasize the need for further research and investigation into dietary inter-relationships and bone health and the effects of vegetarian status, including consumption of soya-based foods, in men as well as women... - Residential area deprivation predicts fruit and vegetable consumption independently of individual educational level and occupational social class: a cross sectional population study in the Norfolk cohort of the European Prospective Investigation into CancShamarina Shohaimi
Institute of Public Health, University of Cambridge, UK
J Epidemiol Community Health 58:686-91. 2004..CONCLUSIONS: Understanding some of the community level barriers to changing health related behaviours may lead to more effective interventions to improving health in the whole community, particularly those who are most vulnerable... - A prospective study of microalbuminuria and incident coronary heart disease and its prognostic significance in a British population: the EPIC-Norfolk studyMatthew F Yuyun
Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom
Am J Epidemiol 159:284-93. 2004..61 (95% CI: 1.19, 2.07). Microalbuminuria may be useful in identifying persons at increased risk of CHD and subsequent death in the general population... - Adjusting for energy intake--what measure to use in nutritional epidemiological studies?Rupert W Jakes
MRC Epidemiology Unit, Strangeways Research Laboratory, Cambridge, CB1 8RN, UK
Int J Epidemiol 33:1382-6. 2004.... - Smoking status and differential white cell count in men and women in the EPIC-Norfolk populationMegan R Smith
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Robinson Way, Cambridge CB2 2SR, UK
Atherosclerosis 169:331-7. 2003..The apparent almost immediate reversibility of effects of smoking on inflammation, as indicated by the WBC count, may help motivate efforts to stop smoking... - Are imprecise methods obscuring a relation between fat and breast cancer?Sheila A Bingham
MRC Dunn Human Nutrition Unit, Welcome Trust MRC Building, Hills Road, CB2 2XY, Cambridge, UK
Lancet 362:212-4. 2003..10 [0.94-1.29], p=0.23). Dietary measurement error might explain the absence of a significant association between dietary fat and breast-cancer risk in cohort studies... - Epidemiologic assessment of sugars consumption using biomarkers: comparisons of obese and nonobese individuals in the European prospective investigation of cancer NorfolkSheila Bingham
Medical Research Council Dunn Human Nutrition Unit University of Cambridge, United Kingdom
Cancer Epidemiol Biomarkers Prev 16:1651-4. 2007..001) despite an inverse association for plasma vitamin C. Nutritional biomarkers of consumption can complement existing methods for assessing cancer risk from diet in epidemiologic studies... - Physical inactivity is associated with lower forced expiratory volume in 1 second : European Prospective Investigation into Cancer-Norfolk Prospective Population StudyRupert W Jakes
Department of Public Health and Primary Care, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge, CB2 2SR, England
Am J Epidemiol 156:139-47. 2002..004 and p < 0.002, respectively). In conclusion, physical activity is associated with higher levels of FEV(1), whereas television viewing is associated with lower levels... - Blood pressure and interactions between the angiotensin polymorphism AGT M235T and sodium intake: a cross-sectional population studyTeresa Norat
MRC Dunn Human Nutrition Unit, Cambridge, United Kingdom
Am J Clin Nutr 88:392-7. 2008..Intervention studies have indicated an interaction between the blood pressure response to a low-sodium or a low-fat and high-fruit and -vegetable diet and the angiotensinogen gene (AGT) polymorphisms G-6A and M235T... - Detection of malondialdehyde DNA adducts in human colorectal mucosa: relationship with diet and the presence of adenomasChiara Leuratti
Medical Research Council Toxicology Unit, University of Leicester, Leicester LE1 9HN, United Kingdom
Cancer Epidemiol Biomarkers Prev 11:267-73. 2002..061). When levels of adducts were compared in individuals with and without adenomas, there was a trend for higher levels in individuals presenting with adenomas especially in the highest category of M(1)-dG adducts (P < 0.005)... - Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population StudyKay Tee Khaw
Clinical Gerontology Unit Box 251, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK cam ac uk
Circulation 116:2694-701. 2007..The relation between endogenous testosterone concentrations and health in men is controversial... - Plasma vitamin C level, fruit and vegetable consumption, and the risk of new-onset type 2 diabetes mellitus: the European prospective investigation of cancer--Norfolk prospective studyAnne Helen Harding
Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, PO Box 285, Hills Road, Cambridge CB2 0QQ, England
Arch Intern Med 168:1493-9. 2008..This study aims to examine whether fruit and vegetable intake and plasma vitamin C level are associated with the risk of incident type 2 diabetes... - Eating out of home and its correlates in 10 European countries. The European Prospective Investigation into Cancer and Nutrition (EPIC) studyPhilippos Orfanos
Department of Hygiene and Epidemiology, University of Athens Medical School, 75 Mikras Asias Street, Athens 11527, Greece
Public Health Nutr 10:1515-25. 2007.... - Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population studyS Matthijs Boekholdt
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
Br J Nutr 96:516-22. 2006..These data suggest that the risk reduction associated with higher ascorbic acid plasma concentrations, a marker of fruit and vegetable intake, is independent of classical risk factors and also independent of CRP concentration... - Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) studyPaula Jakszyn
Department of Epidemiology, Catalan Institute of Oncology, ICO IDIBELL Barcelona, Spain
Carcinogenesis 27:1497-501. 2006..09). Moreover, we observed an interaction between plasma vitamin C and ENOC (P < 0.02). ENOC formation may account for our previously reported association between red and processed meat consumption and gastric cancer risk... - Fish consumption and breast cancer risk. The European Prospective Investigation into Cancer and Nutrition (EPIC)Dagrun Engeset
Institute of Community Medicine, University of Tromsø, Tromsø, Norway
Int J Cancer 119:175-82. 2006..Although the period of follow-up is relatively short, the results provide no evidence for an association between fish intake and breast cancer risk... - Dietary risk factors for the development of inflammatory polyarthritis: evidence for a role of high level of red meat consumptionDorothy J Pattison
University of Manchester, Manchester, UK
Arthritis Rheum 50:3804-12. 2004..CONCLUSION: A high level of red meat consumption may represent a novel risk factor for inflammatory arthritis or may act as a marker for a group of persons with an increased risk from other lifestyle causes... - Cross-sectional association between fish consumption and albuminuria: the European Prospective Investigation of Cancer-Norfolk StudyChee Tin Christine Lee
Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
Am J Kidney Dis 52:876-86. 2008..The aim of this study is to examine the association between fish consumption and albuminuria in individuals with and without diabetes... - Diet in the aetiology of ulcerative colitis: a European prospective cohort studyAndrew R Hart
Department of Population Health, School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
Digestion 77:57-64. 2008..The aim of this study was to examine the prospective relationship between the intake of nutrients and the development of ulcerative colitis in a cohort study... - Dietary beta-cryptoxanthin and inflammatory polyarthritis: results from a population-based prospective studyDorothy J Pattison
Arthritis Research Campaign Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
Am J Clin Nutr 82:451-5. 2005.... - Hormone replacement therapy and symptomatic gallstones - a prospective population study in the EPIC-Norfolk cohortAndrew R Hart
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, UK
Digestion 77:4-9. 2008..The aim of the study was to investigate the relationship between HRT and the development of symptomatic gallstones in a free-living population...