Wenhua Wei

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc High-throughput analysis of epistasis in genome-wide association studies with BiForce
    Attila Gyenesei
    Finnish Microarray and Sequencing Centre, Turku Centre for Biotechnology, University of Turku and Abo Akademi University, 20520, Turku, Finland
    Bioinformatics 28:1957-64. 2012
  2. pmc BiForce Toolbox: powerful high-throughput computational analysis of gene-gene interactions in genome-wide association studies
    Attila Gyenesei
    Finnish Microarray and Sequencing Centre, Turku Centre for Biotechnology, University of Turku, Turku, Finland
    Nucleic Acids Res 40:W628-32. 2012
  3. pmc Genome-wide analysis of epistasis in body mass index using multiple human populations
    Wen Hua Wei
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Eur J Hum Genet 20:857-62. 2012
  4. pmc Properties of local interactions and their potential value in complementing genome-wide association studies
    Wenhua Wei
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e71203. 2013
  5. pmc Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates
    Wenhua Wei
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
    PLoS ONE 6:e23836. 2011

Collaborators

Detail Information

Publications5

  1. pmc High-throughput analysis of epistasis in genome-wide association studies with BiForce
    Attila Gyenesei
    Finnish Microarray and Sequencing Centre, Turku Centre for Biotechnology, University of Turku and Abo Akademi University, 20520, Turku, Finland
    Bioinformatics 28:1957-64. 2012
    ..Fast screening tools are needed to make epistasis analysis routinely available in GWAS...
  2. pmc BiForce Toolbox: powerful high-throughput computational analysis of gene-gene interactions in genome-wide association studies
    Attila Gyenesei
    Finnish Microarray and Sequencing Centre, Turku Centre for Biotechnology, University of Turku, Turku, Finland
    Nucleic Acids Res 40:W628-32. 2012
    ..BiForce Toolbox is easy to use and has been applied in multiple studies of epistasis in large GWAS data sets, identifying interesting interaction signals and pathways...
  3. pmc Genome-wide analysis of epistasis in body mass index using multiple human populations
    Wen Hua Wei
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Eur J Hum Genet 20:857-62. 2012
    ..We conclude that genome-wide analysis of epistasis in multiple populations is an effective approach to provide new insights into the genetic regulation of BMI but requires additional efforts to confirm the findings...
  4. pmc Properties of local interactions and their potential value in complementing genome-wide association studies
    Wenhua Wei
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e71203. 2013
    ..Analysing local interactions is a potentially valuable complement to GWAS and can provide new insights into the biology underlying variation in complex traits. ..
  5. pmc Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates
    Wenhua Wei
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
    PLoS ONE 6:e23836. 2011
    ..We conclude that GWA epistasis analysis is useful despite relatively low power in small isolated populations...