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John C Waterton
Affiliation: University of Manchester
Waterton J, Ho M, Nordenmark L, Jenkins M, Dicarlo J, Guillard G, et al. Repeatability and response to therapy of dynamic contrast-enhanced magnetic resonance imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting. Eur Radiol. 2017;27:3662-3668 pubmed publisher
..DCE-MRI K trans showed fostamatinib inferior to adalimumab after 6Â weeks. â€¢ K trans repeatability coefficient of variation was 30% multicentre. ..
Little R, Barjat H, Hare J, Jenner M, Watson Y, Cheung S, et al. Evaluation of dynamic contrast-enhanced MRI biomarkers for stratified cancer medicine: How do permeability and perfusion vary between human tumours?. Magn Reson Imaging. 2018;46:98-105 pubmed publisher
..Instead, Ktrans is an idiopathic parameter, and, where permeability is important, Ktrans should be measured in each tumour to personalise that treatment. ..