David G Waterman

Summary

Affiliation: University of York
Country: UK

Publications

  1. ncbi request reprint Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain
    David G Waterman
    York Structural Biology Laboratory, University of York, Chemistry Department, York YO10 5YW, UK
    J Mol Biol 356:97-110. 2006
  2. pmc Structure and activity of a novel archaeal β-CASP protein with N-terminal KH domains
    Ana P G Silva
    York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, United Kingdom
    Structure 19:622-32. 2011
  3. doi request reprint Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring
    C Leong Ng
    York Structural Biology Laboratory, Chemistry Department, University of York, York YO10 5YW, England
    Acta Crystallogr D Biol Crystallogr 66:522-8. 2010
  4. pmc Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicus
    Ana P G Silva
    York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, England
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64:1083-6. 2008
  5. pmc Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein
    C Leong Ng
    York Structural Biology Laboratory, Chemistry Department, University of York, York, YO10 5YW, UK
    BMC Struct Biol 9:32. 2009
  6. pmc S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA
    Robert T Byrne
    York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington YO10 5DD, England
    Acta Crystallogr D Biol Crystallogr 69:1090-8. 2013

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain
    David G Waterman
    York Structural Biology Laboratory, University of York, Chemistry Department, York YO10 5YW, UK
    J Mol Biol 356:97-110. 2006
    ..The inaccessibility of U8 in the canonical L-shaped form of tRNA, and the existence of a glycine-rich linker joining the catalytic and RNA-binding moieties of ThiI suggest that structural changes may occur in both molecules upon binding...
  2. pmc Structure and activity of a novel archaeal β-CASP protein with N-terminal KH domains
    Ana P G Silva
    York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, United Kingdom
    Structure 19:622-32. 2011
    ..We hypothesize that this nuclease degrades mRNAs of proteins targeted for degradation and so regulates archaeal RNA turnover, possibly in concert with the exosome...
  3. doi request reprint Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring
    C Leong Ng
    York Structural Biology Laboratory, Chemistry Department, University of York, York YO10 5YW, England
    Acta Crystallogr D Biol Crystallogr 66:522-8. 2010
    ....
  4. pmc Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicus
    Ana P G Silva
    York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, England
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64:1083-6. 2008
    ..The molecule exists as a monomer in solution. X-ray data were collected to 2.85 A resolution from a native crystal belonging to space group P6(1)22 (or P6(5)22), with unit-cell parameters a = 69.9, c = 408.5 A...
  5. pmc Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome protein
    C Leong Ng
    York Structural Biology Laboratory, Chemistry Department, University of York, York, YO10 5YW, UK
    BMC Struct Biol 9:32. 2009
    ..Although genomic and biophysical studies have suggested involvement of this protein in RNA metabolism and in ribosome biogenesis, its interacting partners remain largely unknown...
  6. pmc S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA
    Robert T Byrne
    York Structural Biology Laboratory, Department of Chemistry, University of York, Heslington YO10 5DD, England
    Acta Crystallogr D Biol Crystallogr 69:1090-8. 2013
    ..Indeed, inspection of electron density for one such enzyme with known X-ray structure, PDB entry 1im8, suggests that the active site contains SCM-SAH and not SAM...