Research Topics
| David G WatermanSummaryAffiliation: University of York Country: UK Publications
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Detail Information
Publications
Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domainDavid G Waterman
York Structural Biology Laboratory, University of York, Chemistry Department, York YO10 5YW, UK
J Mol Biol 356:97-110. 2006..The inaccessibility of U8 in the canonical L-shaped form of tRNA, and the existence of a glycine-rich linker joining the catalytic and RNA-binding moieties of ThiI suggest that structural changes may occur in both molecules upon binding...
Structure and activity of a novel archaeal β-CASP protein with N-terminal KH domainsAna P G Silva
York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, United Kingdom
Structure 19:622-32. 2011..We hypothesize that this nuclease degrades mRNAs of proteins targeted for degradation and so regulates archaeal RNA turnover, possibly in concert with the exosome...
Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ringC Leong Ng
York Structural Biology Laboratory, Chemistry Department, University of York, York YO10 5YW, England
Acta Crystallogr D Biol Crystallogr 66:522-8. 2010....
Expression, purification, crystallization and preliminary X-ray studies of the TAN1 orthologue from Methanothermobacter thermautotrophicusAna P G Silva
York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5YW, England
Acta Crystallogr Sect F Struct Biol Cryst Commun 64:1083-6. 2008..The molecule exists as a monomer in solution. X-ray data were collected to 2.85 A resolution from a native crystal belonging to space group P6(1)22 (or P6(5)22), with unit-cell parameters a = 69.9, c = 408.5 A...
Conformational flexibility and molecular interactions of an archaeal homologue of the Shwachman-Bodian-Diamond syndrome proteinC Leong Ng
York Structural Biology Laboratory, Chemistry Department, University of York, York, YO10 5YW, UK
BMC Struct Biol 9:32. 2009..Although genomic and biophysical studies have suggested involvement of this protein in RNA metabolism and in ribosome biogenesis, its interacting partners remain largely unknown...
