N S Ward

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Motor system activation after subcortical stroke depends on corticospinal system integrity
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Brain 129:809-19. 2006
  2. ncbi request reprint Compensatory mechanisms in the aging motor system
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    Ageing Res Rev 5:239-54. 2006
  3. ncbi request reprint Neural plasticity and recovery of function
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Prog Brain Res 150:527-35. 2005
  4. pmc The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical stroke
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, and Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, UK
    Eur J Neurosci 25:1865-73. 2007
  5. ncbi request reprint Future perspectives in functional neuroimaging in stroke recovery
    N S Ward
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, London, UK
    Eura Medicophys 43:285-94. 2007
  6. pmc Mechanisms underlying recovery of motor function after stroke
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Postgrad Med J 81:510-4. 2005
  7. pmc Age-dependent changes in the neural correlates of force modulation: an fMRI study
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neurobiol Aging 29:1434-46. 2008
  8. ncbi request reprint Functional reorganization of the cerebral motor system after stroke
    Nick S Ward
    Institute of Neurology, University College London, London WC1N 3BG, UK
    Curr Opin Neurol 17:725-30. 2004
  9. pmc Longitudinal changes in cerebral response to proprioceptive input in individual patients after stroke: an FMRI study
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Neurorehabil Neural Repair 20:398-405. 2006
  10. pmc Age-related changes in the neural correlates of motor performance
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, UK
    Brain 126:873-88. 2003

Detail Information

Publications31

  1. pmc Motor system activation after subcortical stroke depends on corticospinal system integrity
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Brain 129:809-19. 2006
    ..Secondary motor regions are less efficient at generating motor output so this reorganization can only be considered partially successful in reducing motor impairment after stroke...
  2. ncbi request reprint Compensatory mechanisms in the aging motor system
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    Ageing Res Rev 5:239-54. 2006
    ..The evidence that these changes are compensatory in nature is less clear. Incorporation of behavioural and anatomical data will be required in order to fully interpret the functional imaging results...
  3. ncbi request reprint Neural plasticity and recovery of function
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Prog Brain Res 150:527-35. 2005
    ....
  4. pmc The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical stroke
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, and Department of Brain Repair and Rehabilitation, Institute of Neurology, University College London, London, UK
    Eur J Neurosci 25:1865-73. 2007
    ..These findings suggest that the premotor cortices might play a new and functionally relevant role in controlling force production in patients with more severe corticospinal system disruption...
  5. ncbi request reprint Future perspectives in functional neuroimaging in stroke recovery
    N S Ward
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, London, UK
    Eura Medicophys 43:285-94. 2007
    ....
  6. pmc Mechanisms underlying recovery of motor function after stroke
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Postgrad Med J 81:510-4. 2005
    ....
  7. pmc Age-dependent changes in the neural correlates of force modulation: an fMRI study
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK
    Neurobiol Aging 29:1434-46. 2008
    ..These results indicate that a reduced ability to modulate activity in appropriate motor networks when required may contribute to age-related decline in motor performance...
  8. ncbi request reprint Functional reorganization of the cerebral motor system after stroke
    Nick S Ward
    Institute of Neurology, University College London, London WC1N 3BG, UK
    Curr Opin Neurol 17:725-30. 2004
    ..This understanding may in turn lead to the development of techniques that will drive cerebral reorganization in a way that promotes functional improvement...
  9. pmc Longitudinal changes in cerebral response to proprioceptive input in individual patients after stroke: an FMRI study
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Neurorehabil Neural Repair 20:398-405. 2006
    ..The authors set out to demonstrate the feasibility of using fMRI to investigate mechanisms of recovery in individual patients presenting with severe motor impairment...
  10. pmc Age-related changes in the neural correlates of motor performance
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, UK
    Brain 126:873-88. 2003
    ..These results support the notion that an adaptable and plastic motor network is able to respond to age-related degenerative changes in order to maintain performance levels...
  11. pmc Neural correlates of outcome after stroke: a cross-sectional fMRI study
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Brain 126:1430-48. 2003
    ..These results further our understanding of the recovery process by demonstrating for the first time a clear relationship between task-related activation of the motor system and outcome after stroke...
  12. pmc Neural correlates of motor recovery after stroke: a longitudinal fMRI study
    N S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Brain 126:2476-96. 2003
    ..These results further our understanding of the recovery process by demonstrating for the first time a clear temporal relationship between recovery and task-related activation of the motor system after stroke...
  13. pmc The influence of time after stroke on brain activations during a motor task
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, University College London, London, United Kingdom
    Ann Neurol 55:829-34. 2004
    ..Thus, in those patients with the most to gain from rehabilitation, different therapeutic approaches may be required at different stages after stroke...
  14. pmc Neural correlates of age-related changes in cortical neurophysiology
    P Talelli
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College, London, UK
    Neuroimage 40:1772-81. 2008
    ....
  15. pmc Non-invasive mapping of corticofugal fibres from multiple motor areas--relevance to stroke recovery
    Jennifer M Newton
    Wellcome Department of Imaging Neuroscience, University College London London, UK
    Brain 129:1844-58. 2006
    ..These results confirm that selective disruption of motor corticofugal fibres influences functional reorganization and outcome in individual patients...
  16. pmc How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain?
    Nicolas Lang
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, United Kingdom
    Eur J Neurosci 22:495-504. 2005
    ..The extensive spatial and temporal effects of tDCS need to be taken into account when tDCS is used to modify brain function...
  17. pmc Nonlinear coupling in the human motor system
    Chun Chuan Chen
    Wellcome Trust Centre for Neuroimaging, University College London, London, UK ucl ac uk
    J Neurosci 30:8393-9. 2010
    ..Our results provide empirical evidence for nonlinear coupling among distributed neuronal sources in the motor system and that these play an important role in modulating spectral responses under normal conditions...
  18. pmc The effect of age on task-related modulation of interhemispheric balance
    P Talelli
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Sq, Box 146, London WC1N 3BG, UK
    Exp Brain Res 186:59-66. 2008
    ..The mechanism underlying changes in IHI with advancing age and the association with changes in corticospinal excitability need further investigation...
  19. ncbi request reprint How broad is the phenotype of Hallervorden-Spatz disease?
    S J Hickman
    Department of Neurology, The National Hospital for Neurology and Neurosurgery, London, UK
    Acta Neurol Scand 103:201-3. 2001
    ..The increased availability of MRI has allowed more cases of HSD to be diagnosed in life but as our case illustrates classification of the disease may need to be further examined...
  20. ncbi request reprint The functional anatomy of cerebral reorganisation after focal brain injury
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, National Hospital for Neurology and Neurosurgery, University College London, 12 Queen Square, London WC1N 3BG, UK
    J Physiol Paris 99:425-36. 2006
    ....
  21. pmc Stages of motor output reorganization after hemispheric stroke suggested by longitudinal studies of cortical physiology
    Orlando B C Swayne
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College, 8 11 Queen Square, London, UK
    Cereb Cortex 18:1909-22. 2008
    ....
  22. pmc Dorsal premotor cortex exerts state-dependent causal influences on activity in contralateral primary motor and dorsal premotor cortex
    Sven Bestmann
    Wellcome Trust Centre for Neuroimaging at UCL, Institute of Neurology, University College London, London, UK
    Cereb Cortex 18:1281-91. 2008
    ..We conclude that left PMd can exert state-dependent interhemispheric influences on contralateral cortical motor areas relevant for a current motor task...
  23. ncbi request reprint Plasticity and the functional reorganization of the human brain
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    Int J Psychophysiol 58:158-61. 2005
    ....
  24. ncbi request reprint The neural substrates of motor recovery after focal damage to the central nervous system
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, England
    Arch Phys Med Rehabil 87:S30-5. 2006
    ..To discuss how reorganization of the surviving central nervous system tissue might subserve the improvements in function that are commonly seen over weeks, months, and sometimes years after stroke...
  25. pmc The role of contralesional dorsal premotor cortex after stroke as studied with concurrent TMS-fMRI
    Sven Bestmann
    Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, London, United Kingdom
    J Neurosci 30:11926-37. 2010
    ..cPMd TMS was not found to influence activity in other brain regions in either hemisphere. This state-dependent influence on ipsilesional sensorimotor regions may provide a mechanism by which cPMd supports recovered function after stroke...
  26. pmc Mechanisms underlying recovery of motor function after stroke
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, England
    Arch Neurol 61:1844-8. 2004
    ....
  27. ncbi request reprint Towards a new mapping of brain cortex function
    Nick S Ward
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, UK
    Cerebrovasc Dis 17:35-8. 2004
    ..The dynamic plasticity of functional brain maps provides an exciting opportunity to study these processes...
  28. pmc Low-frequency transcranial magnetic stimulation over left dorsal premotor cortex improves the dynamic control of visuospatially cued actions
    Nick S Ward
    Sobell Department of Motor Neuroscience, University College London, Institute of Neurology, London, United Kingdom
    J Neurosci 30:9216-23. 2010
    ....
  29. ncbi request reprint Recovery of function and plasticity in human brain
    R S J Frackowiak
    Department of Imaging Neuroscience, Institute of Neurology, University College London
    Bull Mem Acad R Med Belg 159:145-55. 2004
  30. ncbi request reprint Isolated familial hypomagnesaemia with novel neurological features: causal link or chance concurrence?
    A J Larner
    St Mary s Hospital, Praed Street, London, UK
    Eur J Neurol 8:495-9. 2001
    ..The pathogenesis of this unusual neurological and ophthalmological syndrome therefore remains uncertain...
  31. ncbi request reprint A positron emission tomographic study in spontaneous migraine
    Shazia K Afridi
    Headache Group, Institute of Neurology and The National Hospital for Neurology and Neurosurgery, London, England
    Arch Neurol 62:1270-5. 2005
    ..Since the seminal observation of brainstem activation in migraine, there has been only a single case substantiating this finding...