Mary Ward

Summary

Affiliation: University of Ulster
Country: UK

Publications

  1. doi request reprint Blood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to intervention with riboflavin: findings of a targeted randomized trial
    Carol P Wilson
    Northern Ireland Centre for Food and Health, University of Ulster, Cromore Rd, Coleraine, BT52 1SA, Northern Ireland
    Hypertension 61:1302-8. 2013
  2. doi request reprint B-vitamins, methylenetetrahydrofolate reductase (MTHFR) and hypertension
    Mary Ward
    Nothern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, UK
    Int J Vitam Nutr Res 81:240-4. 2011
  3. doi request reprint Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up
    Carol P Wilson
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine, Northern Ireland, United Kingdom
    Am J Clin Nutr 95:766-72. 2012
  4. doi request reprint A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy
    Paula Tighe
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland and Biochemistry and Immunology, Trinity College, Dublin, Ireland
    Am J Clin Nutr 93:11-8. 2011
  5. ncbi request reprint Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women
    Julie M W Wallace
    Northern Ireland Centre for Food and Health NICHE, University of Ulster, Coleraine, County Londonderry, UK
    Br J Nutr 108:1264-71. 2012
  6. doi request reprint Nutrition throughout life: folate
    Helene McNulty
    University of Ulster, Coleraine, UK
    Int J Vitam Nutr Res 82:348-54. 2012
  7. doi request reprint C(1) metabolism and CVD outcomes in older adults
    Helene McNulty
    Northern Ireland Centre for Food and Health, University of Ulster, Cromore Road, Coleraine BT52 1SA, UK
    Proc Nutr Soc 71:213-21. 2012
  8. doi request reprint Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C-->T polymorphism in MTHFR
    Geraldine Horigan
    Northern Ireland Centre for Food and Health NICHE, School of Biomedical Sciences, University of Ulster, Coleraine, Ireland
    J Hypertens 28:478-86. 2010
  9. doi request reprint Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery
    William Dickey
    Department of Gastroenterology, Altnagelvin Hospital, Londonderry, Northern Ireland, UK
    Scand J Gastroenterol 43:682-8. 2008
  10. ncbi request reprint Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphism
    Helene McNulty
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland
    Circulation 113:74-80. 2006

Collaborators

Detail Information

Publications23

  1. doi request reprint Blood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to intervention with riboflavin: findings of a targeted randomized trial
    Carol P Wilson
    Northern Ireland Centre for Food and Health, University of Ulster, Cromore Rd, Coleraine, BT52 1SA, Northern Ireland
    Hypertension 61:1302-8. 2013
    ..Clinical Trial Registration- URL: http://www.clinicaltrials.gov. Unique identifier: ISRCTN23620802...
  2. doi request reprint B-vitamins, methylenetetrahydrofolate reductase (MTHFR) and hypertension
    Mary Ward
    Nothern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, UK
    Int J Vitam Nutr Res 81:240-4. 2011
    ....
  3. doi request reprint Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up
    Carol P Wilson
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine, Northern Ireland, United Kingdom
    Am J Clin Nutr 95:766-72. 2012
    ....
  4. doi request reprint A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy
    Paula Tighe
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland and Biochemistry and Immunology, Trinity College, Dublin, Ireland
    Am J Clin Nutr 93:11-8. 2011
    ..The lowest dose of folic acid required to achieve effective reductions in homocysteine is controversial but important for food fortification policy given recent concerns about the potential adverse effects of overexposure to this vitamin...
  5. ncbi request reprint Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women
    Julie M W Wallace
    Northern Ireland Centre for Food and Health NICHE, University of Ulster, Coleraine, County Londonderry, UK
    Br J Nutr 108:1264-71. 2012
    ....
  6. doi request reprint Nutrition throughout life: folate
    Helene McNulty
    University of Ulster, Coleraine, UK
    Int J Vitam Nutr Res 82:348-54. 2012
    ..This review considers the established and emerging roles for folate throughout the lifecycle, and some public health issues related to optimising folate status. ..
  7. doi request reprint C(1) metabolism and CVD outcomes in older adults
    Helene McNulty
    Northern Ireland Centre for Food and Health, University of Ulster, Cromore Road, Coleraine BT52 1SA, UK
    Proc Nutr Soc 71:213-21. 2012
    ..This novel gene-nutrient interaction may provide insights as to the mechanism that links C(1) metabolism with CVD outcomes...
  8. doi request reprint Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C-->T polymorphism in MTHFR
    Geraldine Horigan
    Northern Ireland Centre for Food and Health NICHE, School of Biomedical Sciences, University of Ulster, Coleraine, Ireland
    J Hypertens 28:478-86. 2010
    ..The purpose was to examine the effect of intervention with riboflavin (a cofactor for MTHFR) on blood pressure in patients homozygous (TT genotype) for the common 677C-->T polymorphism in MTHFR...
  9. doi request reprint Homocysteine and related B-vitamin status in coeliac disease: Effects of gluten exclusion and histological recovery
    William Dickey
    Department of Gastroenterology, Altnagelvin Hospital, Londonderry, Northern Ireland, UK
    Scand J Gastroenterol 43:682-8. 2008
    ..The objective of this study was to compare plasma homocysteine levels and biomarker status of metabolically related B vitamins (folate, vitamin B(12), B(6) and riboflavin) in treated and untreated CD patients and healthy controls...
  10. ncbi request reprint Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphism
    Helene McNulty
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, Northern Ireland
    Circulation 113:74-80. 2006
    ....
  11. ncbi request reprint Effect of a voluntary food fortification policy on folate, related B vitamin status, and homocysteine in healthy adults
    Leane Hoey
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 86:1405-13. 2007
    ..Thus, it is virtually nonexistent in Europe, albeit many countries allow food fortification on a voluntary basis...
  12. ncbi request reprint Determining bioavailability of food folates in a controlled intervention study
    Mary P Hannon-Fletcher
    Northern Ireland Centre for Food and Health and the School of Hotel, Leisure, and Tourism, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 80:911-8. 2004
    ..However, many published reports on folate bioavailability are problematic because of several confounding factors...
  13. doi request reprint Folate, related B vitamins, and homocysteine in childhood and adolescence: potential implications for disease risk in later life
    Maeve A Kerr
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, Northern Ireland
    Pediatrics 123:627-35. 2009
    ....
  14. pmc Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study
    Julie Mw Wallace
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 87:391-7. 2008
    ..Both folate and betaine are important predictors of total homocysteine (tHcy) during pregnancy. However, studies to date have only been undertaken in populations with Western dietary patterns...
  15. doi request reprint Impact of continuing folic acid after the first trimester of pregnancy: findings of a randomized trial of Folic Acid Supplementation in the Second and Third Trimesters
    Breige McNulty
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 98:92-8. 2013
    ..Supplementation with folic acid (FA) is recommended worldwide before and during early pregnancy because of its proven effect in preventing neural tube defects, but the role of FA after the 12th gestational week (GW) is much less clear...
  16. doi request reprint Low colonocyte folate is associated with uracil misincorporation and global DNA hypomethylation in human colorectum
    Angela P McGlynn
    Centre for Molecular Biosciences, University of Ulster, Coleraine, Northern Ireland
    J Nutr 143:27-33. 2013
    ..Folate supplementation trials aimed at colon cancer prevention should target individuals with suboptimal folate status...
  17. doi request reprint Women's compliance with current folic acid recommendations and achievement of optimal vitamin status for preventing neural tube defects
    Breige McNulty
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine, Northern Ireland BT52 1SA, UK
    Hum Reprod 26:1530-6. 2011
    ..We investigated compliance of pregnant women with current folic acid recommendations (400 µg/day from preconception to 12 weeks) in relation to achieving a folate status associated with lowest risk of NTDs...
  18. doi request reprint Homocysteine, B-vitamins and CVD
    Helene McNulty
    Northern Ireland Centre for Food and Health NICHE, School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK
    Proc Nutr Soc 67:232-7. 2008
    ..About 10% of the UK and Irish populations have the TT genotype. In the present paper the potential role of folate and related B-vitamins in the primary prevention of CVD and the implications for nutrition policy are explored...
  19. doi request reprint Consumption of wheat aleurone-rich foods increases fasting plasma betaine and modestly decreases fasting homocysteine and LDL-cholesterol in adults
    Ruth K Price
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine, UK
    J Nutr 140:2153-7. 2010
    ..Although this supports a role for betaine in the protective effects of whole grains, concomitant decreases in LDL suggest more than one component or mechanism may be responsible...
  20. pmc Vitamin D and bone health: potential mechanisms
    Eamon Laird
    School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Nutrients 2:693-724. 2010
    ..The immunoregulatory mechanisms of vitamin D may thus modulate the effect of these cytokines on bone health and subsequent fracture risk. Vitamin D, therefore, may influence fracture risk via a number of different mechanisms...
  21. doi request reprint Vitamin B12 and ageing: current issues and interaction with folate
    Catherine F Hughes
    The Northern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, Northern Ireland, UK
    Ann Clin Biochem 50:315-29. 2013
    ..The aim of this review is to examine the known and emerging issues related to vitamin B12 in ageing, its assessment and inter-relationship with folate. ..
  22. ncbi request reprint Homocysteine is lower in the third trimester of pregnancy in women with enhanced folate status from continued folic acid supplementation
    Valerie A Holmes
    Northern Ireland Centre for Food and Health NICHE, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Clin Chem 51:629-34. 2005
    ..Low folate status is associated with an increased concentration of plasma total homocysteine (tHcy), a risk factor associated with pregnancy complications such as preeclampsia...
  23. ncbi request reprint The short-term bioavailabilities of [6S]-5-methyltetrahydrofolate and folic acid are equivalent in men
    Kristina Pentieva
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine, Northern Ireland BT52 1SA
    J Nutr 134:580-5. 2004
    ..Supplementation with the natural folate derivative could have all the beneficial effects associated with FA, but without the potential disadvantage of masking the anemia of vitamin B-12 deficiency...