Research Topics
Genomes and GenesSpecies | Kate A WardSummaryAffiliation: University of Manchester Country: UK Publications
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Detail Information
Publications
Influence of lifestyle factors on quantitative heel ultrasound measurements in middle-aged and elderly menStephen R Pye
ARC Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Oxford Road, Manchester M13 9PT, UK
Calcif Tissue Int 86:211-9. 2010..Modification of lifestyle, including increasing physical activity and stopping smoking, may help optimize bone strength and reduce the risk of fracture in middle-aged and elderly European men...
Bone geometry and density in the skeleton of pre-pubertal gymnasts and school childrenK A Ward
Clinical Radiology, Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
Bone 36:1012-8. 2005..In conclusion, the present study has demonstrated skeletal differences between gymnasts and controls. These differences appear to be site and sex specific...
Bone status during adolescence, pregnancy and lactationKate A Ward
Clinical Radiology, Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
Curr Opin Obstet Gynecol 17:435-9. 2005..This review aims to describe the adaptive mechanisms of the female skeleton to pregnancy and lactation, which ensure optimal fetal skeletal mineralization without compromise to maternal bone strength...
Recommendations for thresholds for cortical bone geometry and density measurement by peripheral quantitative computed tomographyK A Ward
Clinical Radiology, Imaging Science and Biomedical Engineering, Stopford Building, University of Manchester, Oxford Road, Manchester, M13 9PT, UK
Calcif Tissue Int 77:275-80. 2005..The current threshold of 710 mg/mL is inadequate for accurate determination of bone geometry and cortical vBMD. New thresholds of 648 mg/mL for geometry and 1,200 mg/mL for cortical vBMD should be used...
UK reference data for the Hologic QDR Discovery dual-energy x ray absorptiometry scanner in healthy children and young adults aged 6-17 yearsKate A Ward
Department of Clinical Radiology, Imaging Science and Biomedical Engineering, University of Manchester, Manchester, UK
Arch Dis Child 92:53-9. 2007..Ideally, such data should be matched for sex, chronological age, height, weight, pubertal development and ethnicity...
Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in menDelnaz Roshandel
Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, UK
Calcif Tissue Int 89:446-55. 2011..90 [0.92-16.88], P = 0.029). No significant association was observed between RANKL SNPs and pQCT parameters. Our findings suggest that genetic variation in OPG and RANK influences radius vBMD and geometry in men...
A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing StudyDelnaz Roshandel
Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
BMC Med Genet 12:19. 2011..The association between these SNPs and bone mineral density (BMD) measured using dual-energy X-ray absorptiometry (DXA) was also tested...
Genetic variation in the RANKL/RANK/OPG signaling pathway is associated with bone turnover and bone mineral density in menDelnaz Roshandel
Arthritis Research UK, Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
J Bone Miner Res 25:1830-8. 2010..02, p = 6.06 x 10(-8)) and higher ultrasound BMD at the calcaneus (beta = 0.01, p = .037). Our findings suggest that genetic variation in the RANKL/RANK/OPG signaling pathway influences bone turnover and BMD in European men...
Disease activity and severity in early inflammatory arthritis predict hand cortical bone lossStephen R Pye
Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester M13 9PT, UK
Rheumatology (Oxford) 49:1943-8. 2010..To determine the influence of disease-related variables on hand cortical bone loss in women with early inflammatory arthritis (IA), and whether hand cortical bone mass predicts subsequent joint damage...
Vitamin D status and muscle function in post-menarchal adolescent girlsKate A Ward
Imaging Science and Biomedical Engineering, University of Manchester, Manchester, United Kingdom
J Clin Endocrinol Metab 94:559-63. 2009..There has been a resurgence of vitamin D deficiency among infants, toddlers, and adolescents in the United Kingdom. Myopathy is an important clinical symptom of vitamin D deficiency, yet it has not been widely studied...
Postpartum bone status in teenage mothers assessed using peripheral quantitative computed tomographyKate A Ward
Clinical Radiology, Imaging Sciences Research Group, University of Manchester, St Mary s Hospital, Oxford Road, Manchester M13 9PT, UK
J Clin Densitom 12:219-23. 2009..These data suggest that pregnancy might have a detrimental effect on teenage mothers' future skeletal health. The results of this study require confirmation and provide pilot data for further investigations...
Genetic variation in sex hormone genes influences heel ultrasound parameters in middle-aged and elderly men: results from the European Male Aging Study (EMAS)Kate L Limer
ARC Epidemiology Unit, The University of Manchester, Manchester, United Kingdom
J Bone Miner Res 24:314-23. 2009....
Pathogenesis of bone disease in cystic fibrosis: the role of bone size and sarcopeniaZulf Mughal
Department of Paediatric Medicine, Saint Mary's Hospital for Women and Children, Hathersage Road, Manchester M13 0JH, UK
J R Soc Med 99:2-5. 2006
