S Goya Wannamethee

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Alkaline phosphatase, serum phosphate, and incident cardiovascular disease and total mortality in older men
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Health, University College London Medical School, Royal Free Campus, Rowland Hill St, London NW3 2PF, United Kingdom
    Arterioscler Thromb Vasc Biol 33:1070-6. 2013
  2. ncbi Adiposity, adipokines, and risk of incident stroke in older men
    S Goya Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Royal Free Campus, Rowland Hill St, London NW32PF, UK
    Stroke 44:3-8. 2013
  3. ncbi Fibrin D-dimer, tissue-type plasminogen activator, von Willebrand factor, and risk of incident stroke in older men
    S Goya Wannamethee
    Department Primary Care and Population Health, UCL Medical School, London NW32PF, UK
    Stroke 43:1206-11. 2012
  4. ncbi Γ-glutamyltransferase, hepatic enzymes, and risk of incident heart failure in older men
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London Medical School, Royal Free Campus, Rowland Hill St, London NW3 2PF, United Kingdom
    Arterioscler Thromb Vasc Biol 32:830-5. 2012
  5. ncbi N-terminal pro-brain natriuretic Peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, United Kingdom
    J Am Coll Cardiol 58:56-64. 2011
  6. ncbi Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Hampstead Campus, Rowland Hill St, London, NW3 2PF, UK
    Diabetologia 55:80-7. 2012
  7. ncbi Obesity and risk of incident heart failure in older men with and without pre-existing coronary heart disease: does leptin have a role?
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London, London, United Kingdom
    J Am Coll Cardiol 58:1870-7. 2011
  8. ncbi Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College Medical School, London, U K
    Diabetes Care 33:1990-6. 2010
  9. ncbi Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London, Royal Free Campus, London NW3 2PF, England
    Arch Intern Med 171:404-10. 2011
  10. ncbi Relationships of inflammatory and haemostatic markers with social class: results from a population-based study of older men
    Sheena Ramsay
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 197:654-61. 2008

Detail Information

Publications50

  1. ncbi Alkaline phosphatase, serum phosphate, and incident cardiovascular disease and total mortality in older men
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Health, University College London Medical School, Royal Free Campus, Rowland Hill St, London NW3 2PF, United Kingdom
    Arterioscler Thromb Vasc Biol 33:1070-6. 2013
    ..CONCLUSIONS: ALP but not serum phosphate is associated with coronary heart disease risk in elderly men. High levels of ALP and serum phosphate are both associated with increased total mortality...
  2. ncbi Adiposity, adipokines, and risk of incident stroke in older men
    S Goya Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Royal Free Campus, Rowland Hill St, London NW32PF, UK
    Stroke 44:3-8. 2013
    ..The association between adiposity and adipocytes and risk of stroke in older adults is uncertain. We have examined the association between adiposity measures and adipocytes (adiponectin and leptin) with incident stroke events in older men...
  3. ncbi Fibrin D-dimer, tissue-type plasminogen activator, von Willebrand factor, and risk of incident stroke in older men
    S Goya Wannamethee
    Department Primary Care and Population Health, UCL Medical School, London NW32PF, UK
    Stroke 43:1206-11. 2012
    ....
  4. ncbi Γ-glutamyltransferase, hepatic enzymes, and risk of incident heart failure in older men
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London Medical School, Royal Free Campus, Rowland Hill St, London NW3 2PF, United Kingdom
    Arterioscler Thromb Vasc Biol 32:830-5. 2012
    ..We have examined the relationship between GGT, other markers of hepatic function (alanine aminotransferase, aspartate transaminase, and alkaline phosphatase), and incident HF in older men...
  5. ncbi N-terminal pro-brain natriuretic Peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, United Kingdom
    J Am Coll Cardiol 58:56-64. 2011
    ..We aimed to compare the predictive capabilities of N-terminal pro-brain natriuretic peptide (NT-proBNP) and C-reactive protein (CRP) for risk of cardiovascular disease (CVD) in older men with and without pre-existing CVD...
  6. ncbi Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Hampstead Campus, Rowland Hill St, London, NW3 2PF, UK
    Diabetologia 55:80-7. 2012
    ....
  7. ncbi Obesity and risk of incident heart failure in older men with and without pre-existing coronary heart disease: does leptin have a role?
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London, London, United Kingdom
    J Am Coll Cardiol 58:1870-7. 2011
    ....
  8. ncbi Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College Medical School, London, U K
    Diabetes Care 33:1990-6. 2010
    ..We prospectively examined the relationship between lung function and risk of type-2 diabetes and fatal and nonfatal coronary heart disease (CHD) events and investigated the hypothesis that inflammation may underlie these associations...
  9. ncbi Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London, Royal Free Campus, London NW3 2PF, England
    Arch Intern Med 171:404-10. 2011
    ..We have examined the influence of age at onset and duration on the impact of diabetes mellitus on cardiovascular disease risk and all cause-mortality among men aged 60 to 79 years...
  10. ncbi Relationships of inflammatory and haemostatic markers with social class: results from a population-based study of older men
    Sheena Ramsay
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 197:654-61. 2008
    ..The effect of socio-economic gradient on the factor VIII-vWF complex, APC resistance, plasma viscosity and platelet count merits further study...
  11. ncbi The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older non-diabetic men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Atherosclerosis 181:101-8. 2005
    ..We have examined the cross-sectional relationship between insulin resistance, the metabolic syndrome and haemostatic and inflammatory markers...
  12. ncbi Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 83:567-74; quiz 726-7. 2006
    ..It has been suggested that a high dietary intake and high circulating concentrations of vitamin C may protect against ischemic heart disease...
  13. ncbi Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 191:418-26. 2007
    ..We have examined the relationship between leptin and vascular risk factors including insulin resistance, metabolic, inflammatory and haemostatic risk factors...
  14. ncbi Assessing the impact of medication use on trends in major coronary risk factors in older British men: a cohort study
    Sarah L Hardoon
    Department of Primary Care and Population Health, Division of Population Health, UCL, London, UK
    Eur J Cardiovasc Prev Rehabil 17:502-8. 2010
    ..To investigate the role of medication in 20-year trends in blood pressure (BP) and blood lipids in older British men...
  15. ncbi Modifiable lifestyle factors and the metabolic syndrome in older men: Effects of lifestyle changes
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    J Am Geriatr Soc 54:1909-14. 2006
    ..To examine the influence of lifestyle factors and changes in these factors on risk of the metabolic syndrome in elderly men...
  16. ncbi Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 165:2644-50. 2005
    ..We sought to compare metabolic syndrome (MetS) with the Framingham Risk Score (FRS) as predictors of coronary heart disease (CHD), stroke, and type 2 diabetes mellitus (DM2) in middle-aged men...
  17. ncbi Tissue plasminogen activator, von Willebrand factor, and risk of type 2 diabetes in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Diabetes Care 31:995-1000. 2008
    ....
  18. ncbi Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Eur Heart J 26:1765-73. 2005
    ..To examine the associations between cigarette smoking, pipe/cigar smoking, and years since quitting smoking, and inflammatory and haemostatic markers...
  19. ncbi Body fat distribution, body composition, and respiratory function in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 82:996-1003. 2005
    ..Most population studies have reported weak or nonsignificant associations between body mass index (BMI; in kg/m2) and lung function...
  20. ncbi Is the recent rise in type 2 diabetes incidence from 1984 to 2007 explained by the trend in increasing BMI?: evidence from a prospective study of British men
    Sarah L Hardoon
    Division of Population Health, University College London, London, UK
    Diabetes Care 33:1494-6. 2010
    ..To estimate the extent to which increasing BMI may explain the rise in type 2 diabetes incidence in British men from 1984 to 2007...
  21. ncbi Height loss in older men: associations with total mortality and incidence of cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Arch Intern Med 166:2546-52. 2006
    ..We examined the relationships between height loss over 20 years (starting at middle age) and subsequent total mortality and incidence of coronary heart disease and stroke in older men...
  22. ncbi Prediction of coronary heart disease risk by Framingham and SCORE risk assessments varies by socioeconomic position: results from a study in British men
    Sheena E Ramsay
    Department of Primary Care and Population Health, University College London, London, UK
    Eur J Cardiovasc Prev Rehabil 18:186-93. 2011
    ..We examined the performance of coronary risk prediction systems in different socioeconomic groups in British men...
  23. ncbi Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College Medical School, Hampstead Campus, University College London, London, UK
    Diabetes Care 32:1823-5. 2009
    ..To examine the relationship between dietary fiber and the risk of type 2 diabetes in older men and the role of hepatic and inflammatory markers...
  24. ncbi Migration within Great Britain and cardiovascular disease: early life and adult environmental factors
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Epidemiol 31:1054-60. 2002
    ..To examine the relative contributions of early life and adult life factors to risk of cardiovascular disease (CVD) in middle-aged men using migration within Great Britain (GB)...
  25. ncbi Adipokines and risk of type 2 diabetes in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Diabetes Care 30:1200-5. 2007
    ..The aim was to assess the relationship between adipokines, including interleukin (IL)-6, leptin, and adiponectin, with development of type 2 diabetes and assess the role of obesity and insulin resistance in these relationships...
  26. ncbi Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke
    Barbara J Jefferis
    UCL Department Primary Care and Population Health, Royal Free and University College Medical School, London, UK
    Atherosclerosis 205:302-8. 2009
    ....
  27. ncbi Overweight and obesity and weight change in middle aged men: impact on cardiovascular disease and diabetes
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    J Epidemiol Community Health 59:134-9. 2005
    ..The benefit of weight reduction for cardiovascular disease (CVD) outcomes remains uncertain...
  28. ncbi Weight change, weight fluctuation, and mortality
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 162:2575-80. 2002
    ..To examine the relation between weight change and weight fluctuation (cycling) and mortality in middle-aged men...
  29. ncbi Serum albumin and risk of stroke, coronary heart disease, and mortality: the role of cigarette smoking
    A Gerald Shaper
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowlands Hill Street, London NW3 2PF, UK
    J Clin Epidemiol 57:195-202. 2004
    ..These relationships have been examined with specific focus on the role of cigarette smoking...
  30. ncbi Interleukin 18 and coronary heart disease: prospective study and systematic review
    Barbara J M H Jefferis
    Department of Primary Care and Population Health, University College London, London NW3 2PF, UK
    Atherosclerosis 217:227-33. 2011
    ..We report new data from the largest prospective study to date, which are combined with data from all published prospective studies in a meta-analysis...
  31. ncbi Decreased muscle mass and increased central adiposity are independently related to mortality in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 86:1339-46. 2007
    ..Aging is associated with significant changes in body composition. Body mass index (BMI; in kg/m(2)) is not an accurate indicator of overweight and obesity in the elderly...
  32. ncbi Changes in environmental tobacco smoke (ETS) exposure over a 20-year period: cross-sectional and longitudinal analyses
    Barbara J Jefferis
    British Regional Heart Study, UCL Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Addiction 104:496-503. 2009
    ..To examine long-term changes in environmental tobacco smoke (ETS) exposure in British men between 1978 and 2000, using serum cotinine...
  33. ncbi Alcohol, body weight, and weight gain in middle-aged men
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    Am J Clin Nutr 77:1312-7. 2003
    ..There is uncertainty as to whether regular alcohol consumption contributes directly to weight gain and the risk of obesity...
  34. ncbi Measures of adiposity in the identification of metabolic abnormalities in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 81:1313-21. 2005
    ..Body mass index (BMI; in kg/m(2)) is considered a poor indicator of overall and abdominal obesity in the elderly...
  35. ncbi Reasons for intentional weight loss, unintentional weight loss, and mortality in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Arch Intern Med 165:1035-40. 2005
    ....
  36. ncbi Cigarette smoking and serum liver enzymes: the role of alcohol and inflammation
    S Goya Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Royal Free Campus, London, UK
    Ann Clin Biochem 47:321-6. 2010
    ..We have examined the relationship between cigarette smoking and liver enzymes and the role of alcohol and C-reactive protein (CRP), a marker of inflammation...
  37. ncbi Lifestyle and cardiovascular disease in middle-aged British men: the effect of adjusting for within-person variation
    Jonathan Robert Emberson
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Eur Heart J 26:1774-82. 2005
    ....
  38. ncbi How much of the recent decline in the incidence of myocardial infarction in British men can be explained by changes in cardiovascular risk factors? Evidence from a prospective population-based study
    Sarah L Hardoon
    Department of Primary Care and Population Sciences, UCL, London, United Kingdom
    Circulation 117:598-604. 2008
    ..The incidence of myocardial infarction (MI) in Britain has fallen markedly in recent years. Few studies have investigated the extent to which this decline can be explained by concurrent changes in major cardiovascular risk factors...
  39. ncbi From a postal questionnaire of older men, healthy lifestyle factors reduced the onset of and may have increased recovery from mobility limitation
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    J Clin Epidemiol 58:831-40. 2005
    ..We have examined predictors of the onset of and recovery from mobility limitation and the association between lifestyle changes in later life and mobility status...
  40. ncbi Prospective study of IL-18 and risk of MI and stroke in men and women aged 60-79 years: a nested case-control study
    Barbara J Jefferis
    British Regional Heart Study, UCL Department of Primary Care and Population Health, UCL, London NW3 2PF, UK
    Cytokine 61:513-20. 2013
    ..We examined prospective associations between levels of serum IL-18 and new CHD and stroke events in older men and women from a general population...
  41. ncbi Longitudinal associations between changes in physical activity and onset of type 2 diabetes in older British men: the influence of adiposity
    Barbara J Jefferis
    Department of Primary Care and Population Health, UCL Medical School, London, UK
    Diabetes Care 35:1876-83. 2012
    ..To determine how much physical activity (PA) is needed to protect against diabetes onset in older adults, whether protection is greater among overweight individuals, and whether taking up moderate activity in later life is beneficial...
  42. ncbi Physical activity and hemostatic and inflammatory variables in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, UK
    Circulation 105:1785-90. 2002
    ..Hemostatic and inflammatory markers have been linked with risk of cardiovascular disease. We therefore examined the relationship between physical activity and hemostatic and inflammatory variables...
  43. ncbi Physical activity and cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, England
    Semin Vasc Med 2:257-66. 2002
    ..Current evidence supports the recommended guidelines of 30 minutes of moderate physical activity on most days of the week in both primary and secondary prevention of CHD...
  44. ncbi Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 167:1510-7. 2007
    ..We examined the relationship between adiponectin levels and mortality in older men with and without diagnosed cardiovascular disease (CVD) and heart failure...
  45. ncbi Commentary: Alcohol and mortality: diminishing returns for benefits of alcohol
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    Int J Epidemiol 34:205-6. 2005
  46. ncbi Alcohol intake and 8-year weight gain in women: a prospective study
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, United Kingdom
    Obes Res 12:1386-96. 2004
    ..To examine prospectively the relationship between alcohol and 8-year weight gain in women...
  47. ncbi Interventions to increase adiponectin may be associated with increased coronary heart disease in older adults
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, University College Medical School, Royal Free Campus, London, UK
    Future Cardiol 5:19-22. 2009
    ..Until we unravel this paradox, therapeutic interventions aimed at enhancing adiponectin levels for cardiovascular disease prevention in older subjects may be undesirable...
  48. ncbi Alcohol drinking patterns and risk of type 2 diabetes mellitus among younger women
    S Goya Wannamethee
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Arch Intern Med 163:1329-36. 2003
    ..To examine the relationship between alcohol consumption and the incidence of type 2 diabetes mellitus among relatively young and middle-aged women...
  49. ncbi Commentary: Prevention of coronary heart disease in South Asia--containing the physical inactivity epidemic
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    Int J Epidemiol 33:767-8. 2004
  50. ncbi Serum uric acid and risk of coronary heart disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Curr Pharm Des 11:4125-32. 2005
    ..In summary, there is little support for an independent causal role for SUA in the development of CHD. However, SUA may provide useful prognostic information in subjects with hypertension and vascular disease...