S G Wannamethee

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 191:418-26. 2007
  2. ncbi Reasons for intentional weight loss, unintentional weight loss, and mortality in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Arch Intern Med 165:1035-40. 2005
  3. ncbi Interventions to increase adiponectin may be associated with increased coronary heart disease in older adults
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, University College Medical School, Royal Free Campus, London, UK
    Future Cardiol 5:19-22. 2009
  4. ncbi Serum uric acid and risk of coronary heart disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Curr Pharm Des 11:4125-32. 2005
  5. ncbi Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, U K
    Diabetes Care 28:2913-8. 2005
  6. ncbi Body fat distribution, body composition, and respiratory function in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 82:996-1003. 2005
  7. ncbi Physical activity and cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, England
    Semin Vasc Med 2:257-66. 2002
  8. ncbi Alcohol and adiposity: effects of quantity and type of drink and time relation with meals
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 29:1436-44. 2005
  9. ncbi From a postal questionnaire of older men, healthy lifestyle factors reduced the onset of and may have increased recovery from mobility limitation
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    J Clin Epidemiol 58:831-40. 2005
  10. ncbi Measures of adiposity in the identification of metabolic abnormalities in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 81:1313-21. 2005

Detail Information

Publications94

  1. ncbi Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 191:418-26. 2007
    ..We have examined the relationship between leptin and vascular risk factors including insulin resistance, metabolic, inflammatory and haemostatic risk factors...
  2. ncbi Reasons for intentional weight loss, unintentional weight loss, and mortality in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Arch Intern Med 165:1035-40. 2005
    ....
  3. ncbi Interventions to increase adiponectin may be associated with increased coronary heart disease in older adults
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, University College Medical School, Royal Free Campus, London, UK
    Future Cardiol 5:19-22. 2009
    ..Until we unravel this paradox, therapeutic interventions aimed at enhancing adiponectin levels for cardiovascular disease prevention in older subjects may be undesirable...
  4. ncbi Serum uric acid and risk of coronary heart disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Curr Pharm Des 11:4125-32. 2005
    ..In summary, there is little support for an independent causal role for SUA in the development of CHD. However, SUA may provide useful prognostic information in subjects with hypertension and vascular disease...
  5. ncbi Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older men
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, U K
    Diabetes Care 28:2913-8. 2005
    ..We have examined the relationship between hepatic enzymes, the metabolic syndrome, insulin resistance, and type 2 diabetes and assessed the potential of hepatic enzyme measurements in determining diabetes risk...
  6. ncbi Body fat distribution, body composition, and respiratory function in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 82:996-1003. 2005
    ..Most population studies have reported weak or nonsignificant associations between body mass index (BMI; in kg/m2) and lung function...
  7. ncbi Physical activity and cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, England
    Semin Vasc Med 2:257-66. 2002
    ..Current evidence supports the recommended guidelines of 30 minutes of moderate physical activity on most days of the week in both primary and secondary prevention of CHD...
  8. ncbi Alcohol and adiposity: effects of quantity and type of drink and time relation with meals
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 29:1436-44. 2005
    ..It has been suggested that the effects of alcohol on body weight and fat distribution may be influenced by the quantity and type of drink and may differ according to whether the alcohol is consumed with meals or not...
  9. ncbi From a postal questionnaire of older men, healthy lifestyle factors reduced the onset of and may have increased recovery from mobility limitation
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    J Clin Epidemiol 58:831-40. 2005
    ..We have examined predictors of the onset of and recovery from mobility limitation and the association between lifestyle changes in later life and mobility status...
  10. ncbi Measures of adiposity in the identification of metabolic abnormalities in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 81:1313-21. 2005
    ..Body mass index (BMI; in kg/m(2)) is considered a poor indicator of overall and abdominal obesity in the elderly...
  11. ncbi The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older non-diabetic men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Atherosclerosis 181:101-8. 2005
    ..We have examined the cross-sectional relationship between insulin resistance, the metabolic syndrome and haemostatic and inflammatory markers...
  12. doi High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men: does NT-proBNP help to explain this association?
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Health, UCL, London, UK
    Eur J Cardiovasc Prev Rehabil 18:65-71. 2011
    ..We examined whether N-terminal pro-brain natriuretic peptide (NT-proBNP), a marker of cardiac dysfunction, may help explain this relationship...
  13. ncbi Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Eur Heart J 26:1765-73. 2005
    ..To examine the associations between cigarette smoking, pipe/cigar smoking, and years since quitting smoking, and inflammatory and haemostatic markers...
  14. pmc Overweight and obesity and weight change in middle aged men: impact on cardiovascular disease and diabetes
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    J Epidemiol Community Health 59:134-9. 2005
    ..The benefit of weight reduction for cardiovascular disease (CVD) outcomes remains uncertain...
  15. ncbi Commentary: Alcohol and mortality: diminishing returns for benefits of alcohol
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    Int J Epidemiol 34:205-6. 2005
  16. pmc Cardiovascular disease incidence and mortality in older men with diabetes and in men with coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Heart 90:1398-403. 2004
    ..To examine the relation of diabetes and coronary heart disease (CHD; myocardial infarction (MI) or angina) to the incidence of major CHD and stroke events and total mortality...
  17. ncbi Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 83:567-74; quiz 726-7. 2006
    ..It has been suggested that a high dietary intake and high circulating concentrations of vitamin C may protect against ischemic heart disease...
  18. pmc Assessing prediction of diabetes in older adults using different adiposity measures: a 7 year prospective study in 6,923 older men and women
    S G Wannamethee
    Department of Primary Care and Population Health, University College London Medical School, Hampstead Campus, Rowland Hill St, London NW3 2PF, UK
    Diabetologia 53:890-8. 2010
    ..The aim of this study was to examine whether waist circumference (WC) or WHR improve diabetes prediction beyond body mass index in older men and women, and to define optimal cut-off points...
  19. doi The metabolic syndrome and cardiovascular risk in the British Regional Heart Study
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 32:S25-9. 2008
    ..To evaluate the metabolic syndrome as an overall risk assessment tool for cardiovascular disease (CVD) and diabetes in middle-aged British men...
  20. doi The value of gamma-glutamyltransferase in cardiovascular risk prediction in men without diagnosed cardiovascular disease or diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 201:168-75. 2008
    ..We have examined the relationship between gamma-glutamyltransferase (GGT) and major coronary heart disease (CHD) and stroke events and cardiovascular mortality in men free of cardiovascular disease (CVD)...
  21. pmc Associations between dietary fiber and inflammation, hepatic function, and risk of type 2 diabetes in older men: potential mechanisms for the benefits of fiber on diabetes risk
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College Medical School, Hampstead Campus, University College London, London, UK
    Diabetes Care 32:1823-5. 2009
    ..To examine the relationship between dietary fiber and the risk of type 2 diabetes in older men and the role of hepatic and inflammatory markers...
  22. ncbi Tissue plasminogen activator, von Willebrand factor, and risk of type 2 diabetes in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK
    Diabetes Care 31:995-1000. 2008
    ....
  23. pmc Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Royal Free Campus, London NW3 2PF, UK
    J Thromb Haemost 7:1605-11. 2009
    ....
  24. ncbi Decreased muscle mass and increased central adiposity are independently related to mortality in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Clin Nutr 86:1339-46. 2007
    ..Aging is associated with significant changes in body composition. Body mass index (BMI; in kg/m(2)) is not an accurate indicator of overweight and obesity in the elderly...
  25. ncbi Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 167:1510-7. 2007
    ..We examined the relationship between adiponectin levels and mortality in older men with and without diagnosed cardiovascular disease (CVD) and heart failure...
  26. ncbi Inter-relationships of interleukin-6, cardiovascular risk factors and the metabolic syndrome among older men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    J Thromb Haemost 5:1637-43. 2007
    ..Interleukin-6 (IL-6) has been implicated in the development of cardiovascular disease. We have examined the relationship between plasma IL-6 and insulin resistance, and metabolic, inflammatory and hemostatic markers...
  27. ncbi Adipokines and risk of type 2 diabetes in older men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Diabetes Care 30:1200-5. 2007
    ..The aim was to assess the relationship between adipokines, including interleukin (IL)-6, leptin, and adiponectin, with development of type 2 diabetes and assess the role of obesity and insulin resistance in these relationships...
  28. ncbi Associations of adiponectin with metabolic and vascular risk parameters in the British Regional Heart Study reveal stronger links to insulin resistance-related than to coronory heart disease risk-related parameters
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Obes (Lond) 31:1089-98. 2007
    ..We examined the relationship between adiponectin and insulin resistance, metabolic, inflammatory and haemostatic risk factors and hepatic function...
  29. ncbi Modifiable lifestyle factors and the metabolic syndrome in older men: Effects of lifestyle changes
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    J Am Geriatr Soc 54:1909-14. 2006
    ..To examine the influence of lifestyle factors and changes in these factors on risk of the metabolic syndrome in elderly men...
  30. ncbi Height loss in older men: associations with total mortality and incidence of cardiovascular disease
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Arch Intern Med 166:2546-52. 2006
    ..We examined the relationships between height loss over 20 years (starting at middle age) and subsequent total mortality and incidence of coronary heart disease and stroke in older men...
  31. ncbi Renal function and cardiovascular mortality in elderly men: the role of inflammatory, procoagulant, and endothelial biomarkers
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and, University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Eur Heart J 27:2975-81. 2006
    ..To assess the extent to which inflammatory, procoagulant, and endothelial biomarkers modify the relationship between diminished renal function and cardiovascular mortality...
  32. ncbi Alcohol intake and 8-year weight gain in women: a prospective study
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, United Kingdom
    Obes Res 12:1386-96. 2004
    ..To examine prospectively the relationship between alcohol and 8-year weight gain in women...
  33. ncbi Insulin resistance, haemostatic and inflammatory markers and coronary heart disease risk factors in Type 2 diabetic men with and without coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London, NW3 2PF, UK
    Diabetologia 47:1557-65. 2004
    ..We have examined markers of haemostasis and inflammation in men with diabetes, coronary heart disease (CHD) or both, and assessed their associations with insulin resistance in men with Type 2 diabetes...
  34. ncbi Migration within Great Britain and cardiovascular disease: early life and adult environmental factors
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Int J Epidemiol 31:1054-60. 2002
    ..To examine the relative contributions of early life and adult life factors to risk of cardiovascular disease (CVD) in middle-aged men using migration within Great Britain (GB)...
  35. pmc Alcohol consumption and the incidence of type II diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    J Epidemiol Community Health 56:542-8. 2002
    ..This study examines the relation between alcohol and type II diabetes and the possible mediating effects of HDL-cholesterol and serum insulin...
  36. ncbi Physical activity and hemostatic and inflammatory variables in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, UK
    Circulation 105:1785-90. 2002
    ..Hemostatic and inflammatory markers have been linked with risk of cardiovascular disease. We therefore examined the relationship between physical activity and hemostatic and inflammatory variables...
  37. pmc Taking up regular drinking in middle age: effect on major coronary heart disease events and mortality
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Heart 87:32-6. 2002
    ..To examine effects of taking up regular drinking by middle aged non-drinkers and occasional drinkers on major coronary heart disease events and total mortality...
  38. doi The potential for a two-stage diabetes risk algorithm combining non-laboratory-based scores with subsequent routine non-fasting blood tests: results from prospective studies in older men and women
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Glasgow, UK
    Diabet Med 28:23-30. 2011
    ..To develop strategies based on simple clinical assessment and blood markers to identify older individuals at high risk for Type 2 diabetes...
  39. ncbi Smoking as a modifiable risk factor for type 2 diabetes in middle-aged men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, U K
    Diabetes Care 24:1590-5. 2001
    ..To examine the effects of cigarette smoking, giving up smoking, and primary or secondary pipe or cigar smoking on the risk of type 2 diabetes...
  40. ncbi Weight change, body weight and mortality: the impact of smoking and ill health
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, Rowland Hill St, London NW3 2PF, UK
    Int J Epidemiol 30:777-86. 2001
    ....
  41. ncbi Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke, and type 2 diabetes mellitus
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 165:2644-50. 2005
    ..We sought to compare metabolic syndrome (MetS) with the Framingham Risk Score (FRS) as predictors of coronary heart disease (CHD), stroke, and type 2 diabetes mellitus (DM2) in middle-aged men...
  42. ncbi Physical activity in the prevention of cardiovascular disease: an epidemiological perspective
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, England
    Sports Med 31:101-14. 2001
    ..Taking up regular light or moderate physical activity in middle or older age confers significant benefit for CVD and all-cause mortality...
  43. ncbi Weight change, weight fluctuation, and mortality
    S Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 162:2575-80. 2002
    ..To examine the relation between weight change and weight fluctuation (cycling) and mortality in middle-aged men...
  44. ncbi Serum uric acid is not an independent risk factor for coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Curr Hypertens Rep 3:190-6. 2001
    ..This review finds little support for an independent causal role for serum uric acid in the development of coronary heart disease...
  45. ncbi Overweight and obesity and the burden of disease and disability in elderly men
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    Int J Obes Relat Metab Disord 28:1374-82. 2004
    ..To examine the prevalence of disease burden and disability associated with overweight and obesity in men aged 60-79 y and to assess whether the current WHO weight guidelines are appropriate in the elderly...
  46. ncbi Commentary: Prevention of coronary heart disease in South Asia--containing the physical inactivity epidemic
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK
    Int J Epidemiol 33:767-8. 2004
  47. ncbi The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men
    Sasiwarang Goya Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill St, London, NW3 2PF, UK
    Thromb Haemost 90:1080-7. 2003
    ..Wine has effects that may confer greater protection than other alcoholic beverages...
  48. doi Cigarette smoking and serum liver enzymes: the role of alcohol and inflammation
    S Goya Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Royal Free Campus, London, UK
    Ann Clin Biochem 47:321-6. 2010
    ..We have examined the relationship between cigarette smoking and liver enzymes and the role of alcohol and C-reactive protein (CRP), a marker of inflammation...
  49. ncbi Birthweight of offspring and paternal insulin resistance and paternal diabetes in late adulthood: cross sectional survey
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, Rowland Hill St, NW3 2PF London, UK
    Diabetologia 47:12-8. 2004
    ..To confirm this we examined the association between offspring birthweight and paternal insulin resistance and diabetes in late adulthood...
  50. ncbi Alcohol drinking patterns and risk of type 2 diabetes mellitus among younger women
    S Goya Wannamethee
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Arch Intern Med 163:1329-36. 2003
    ..To examine the relationship between alcohol consumption and the incidence of type 2 diabetes mellitus among relatively young and middle-aged women...
  51. ncbi Alcohol, body weight, and weight gain in middle-aged men
    S Goya Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    Am J Clin Nutr 77:1312-7. 2003
    ..There is uncertainty as to whether regular alcohol consumption contributes directly to weight gain and the risk of obesity...
  52. doi Prospective study of seasonal patterns in hemostatic factors in older men and their relation to excess winter coronary heart disease deaths
    M A Ghebre
    Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
    J Thromb Haemost 10:352-8. 2012
    ..The potential contributions of these hemostatic activation measures to excess winter mortality are unknown...
  53. ncbi Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women
    B J Jefferis
    Department of Primary Care and Population Health, UCL Medical School, Rowland Hill Street, London, UK
    J Thromb Haemost 9:1452-9. 2011
    ..CD40 ligand(CD40L) is implicated in atherosclerotic plaque formation...
  54. ncbi Serum true insulin concentration and the risk of clinical non-insulin dependent diabetes during long-term follow-up
    I J Perry
    Department of Primary Care and Population Sciences, The Royal Free Hospital School of Medicine, London, UK
    Int J Epidemiol 28:735-41. 1999
    ..Using a specific assay, we have addressed the hypothesis that an elevation of serum true insulin concentration, reflecting insulin resistance, is an early event in the pathogenesis of NIDDM...
  55. doi Do women exhibit greater differences in established and novel risk factors between diabetes and non-diabetes than men? The British Regional Heart Study and British Women's Heart Health Study
    S G Wannamethee
    Department of Primary Care and Population Health, UCL Medical School, Hampstead Campus, Rowland Hill St, London, NW3 2PF, UK
    Diabetologia 55:80-7. 2012
    ....
  56. pmc Are childhood socio-economic circumstances related to coronary heart disease risk? Findings from a population-based study of older men
    Sheena E Ramsay
    Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, Rowland Hill Street, London, UK
    Int J Epidemiol 36:560-6. 2007
    ..We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors...
  57. pmc Extent of social inequalities in disability in the elderly: results from a population-based study of British men
    Sheena E Ramsay
    Division of Population Health, University College London, St George s University of London, London, UK
    Ann Epidemiol 18:896-903. 2008
    ..Little is known about social inequalities in disability in the elderly. We examined the extent and determinants of socioeconomic inequalities in disability and functional limitation in elderly men in Britain...
  58. pmc Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors
    S E Ramsay
    Division of Population Health, UCL, London, UK
    J Thromb Haemost 7:1779-86. 2009
    ..Little is also known about the contributions that novel coronary risk factors (particularly inflammatory/hemostatic markers) make to socioeconomic inequalities in CHD...
  59. ncbi Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, England
    Arch Intern Med 160:2108-16. 2000
    ..To examine the role of nonfasting serum insulin level and components of the insulin resistance syndrome in the relationship between physical activity and the incidence of coronary heart disease and type 2 diabetes...
  60. pmc Cotinine-assessed second-hand smoke exposure and risk of cardiovascular disease in older adults
    B J Jefferis
    UCL Department of Primary Care and Population Health, UCL Medical School, London, UK
    Heart 96:854-9. 2010
    ..To examine whether second-hand smoke (SHS) exposure measured by serum cotinine is associated with increased coronary heart disease (CHD) and stroke risk among contemporary older British adults...
  61. ncbi The relations of body composition and adiposity measures to ill health and physical disability in elderly men
    Sheena E Ramsay
    Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, London, United Kingdom
    Am J Epidemiol 164:459-69. 2006
    ..Prevention of weight gain with increasing age is likely to reduce morbidity and disability among older men...
  62. ncbi HDL-Cholesterol, total cholesterol, and the risk of stroke in middle-aged British men
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Stroke 31:1882-8. 2000
    ..The purpose of this study was to examine the relation between serum HDL cholesterol and total cholesterol and risk of stroke...
  63. ncbi Physical activity and mortality in older men with diagnosed coronary heart disease
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Circulation 102:1358-63. 2000
    ..We have studied the relations between physical activity, types of physical activity, and changes in physical activity and all-cause mortality in men with established coronary heart disease (CHD)...
  64. pmc Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women
    B J Jefferis
    Department Primary Care and Population Health, UCL Medical School, Rowland Hill St, NW3 2PF, London, UK
    Atherosclerosis 208:550-6. 2010
    ..Therefore we investigate associations between SHS exposure and CHD risk factors, to clarify how SHS exposure may raise risk of CHD...
  65. pmc Social class differences in secular trends in established coronary risk factors over 20 years: a cohort study of British men from 1978-80 to 1998-2000
    Sheena E Ramsay
    Department of Primary Care and Population Health, University College London, London, United Kingdom
    PLoS ONE 6:e19742. 2011
    ..This study examined whether changes in established coronary risk factors in Britain over 20 years between 1978-80 and 1998-2000 differed between socioeconomic groups...
  66. ncbi Variability of angina symptoms and the risk of major ischemic heart disease events
    F C Lampe
    Cardiovascular Research Unit, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, United Kingdom
    Am J Epidemiol 153:1173-82. 2001
    ..In middle-aged men, exertional chest pain is a strong indicator of major coronary risk but frequently appears transient in the longer term. Persistently reported symptoms are associated with severe disease and a poor prognosis...
  67. pmc Type of alcoholic drink and risk of major coronary heart disease events and all-cause mortality
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, England
    Am J Public Health 89:685-90. 1999
    ..This study examined the effects of beer, spirits, and wine drinking on coronary heart disease (CHD) events (fatal and nonfatal) and all-cause mortality...
  68. ncbi Pipe and cigar smoking and major cardiovascular events, cancer incidence and all-cause mortality in middle-aged British men
    A G Shaper
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, 8 Wentworth Hall, The Ridgeway, Mill Hill, London NW7 1RJ, UK
    Int J Epidemiol 32:802-8. 2003
    ..Pipe and cigar smoking are still regarded by many as less hazardous to health than cigarette smoking...
  69. ncbi Serum albumin and risk of stroke, coronary heart disease, and mortality: the role of cigarette smoking
    A Gerald Shaper
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowlands Hill Street, London NW3 2PF, UK
    J Clin Epidemiol 57:195-202. 2004
    ..These relationships have been examined with specific focus on the role of cigarette smoking...
  70. pmc Alcohol intake and mortality in middle aged men with diagnosed coronary heart disease
    A G Shaper
    Department of Primary Care and Population Sciences, Royal Free and University College Medical Schools, Rowland Hill Street, London NW3 2PF, UK
    Heart 83:394-9. 2000
    ..To examine the effects of alcohol on risk of mortality from coronary heart disease (CHD), cardiovascular disease, and all causes in men with established CHD...
  71. ncbi Nonfasting serum glucose and insulin concentrations and the risk of stroke
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, England
    Stroke 30:1780-6. 1999
    ..We have examined the relationship between established diabetes, nonfasting serum glucose and serum insulin concentrations, and subsequent risk of stroke...
  72. ncbi Lifestyle and cardiovascular disease in middle-aged British men: the effect of adjusting for within-person variation
    Jonathan Robert Emberson
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Eur Heart J 26:1774-82. 2005
    ....
  73. ncbi Evidence of an accelerating increase in prevalence of diagnosed Type 2 diabetes in British men, 1978-2005
    M C Thomas
    Research Department of Primary Care and Population Health, University College London, UK
    Diabet Med 26:766-72. 2009
    ..This study aims to estimate the extent of the increase in prevalence of diagnosed Type 2 diabetes in British men between 1978 and 2005...
  74. pmc Is socioeconomic position related to the prevalence of metabolic syndrome?: influence of social class across the life course in a population-based study of older men
    Sheena E Ramsay
    Division of Population Health, University College London, London, UK
    Diabetes Care 31:2380-2. 2008
    ..To examine whether adult social class and childhood social class are related to metabolic syndrome in later life, independent of adult behavioral factors...
  75. ncbi Alcohol intake in middle age and risk of cardiovascular disease and mortality: accounting for intake variation over time
    J R Emberson
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Am J Epidemiol 161:856-63. 2005
    ..The findings suggest that considerable caution may be needed before any recommendations regarding acceptable limits of alcohol consumption are made...
  76. pmc Missed opportunities for secondary prevention of cerebrovascular disease in elderly British men from 1999 to 2005: a population-based study
    Sheena E Ramsay
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, UCL Hampstead Campus, Rowland Hill Street, London NW3 2PF, UK
    J Public Health (Oxf) 29:251-7. 2007
    ..We examined patterns in medication use for secondary prevention of cerebrovascular disease in older British men from 1999 to 2005, and investigated socio-demographic and disease-related influences on medication use...
  77. pmc Are social inequalities in mortality in Britain narrowing? Time trends from 1978 to 2005 in a population-based study of older men
    S E Ramsay
    Department of Primary Care and Population Sciences, Royal Free Hospital and University College Medical School, London, UK
    J Epidemiol Community Health 62:75-80. 2008
    ..To examine whether social inequalities in all-cause and coronary heart disease (CHD) mortality in Britain have reduced between 1978 and 2005...
  78. doi Social engagement and the risk of cardiovascular disease mortality: results of a prospective population-based study of older men
    Sheena Ramsay
    Department of Primary Care and Population Sciences, University College London, London, UK
    Ann Epidemiol 18:476-83. 2008
    ....
  79. pmc Geographic variation in incidence of coronary heart disease in Britain: the contribution of established risk factors
    R W Morris
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK
    Heart 86:277-83. 2001
    ..To determine the extent to which geographic variation in the incidence of major coronary heart disease (CHD) in Great Britain may be explained by established risk factors...
  80. ncbi Measuring the prevalence of disease in middle-aged British men
    M Walker
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Royal Free Campus, London
    J R Coll Physicians Lond 33:351-8. 1999
    ..To identify and validate a measure of disease prevalence in a town or other subpopulation for the purpose of estimating variations in morbidity and health care needs between groups...
  81. doi Impact of diabetes on cardiovascular disease risk and all-cause mortality in older men: influence of age at onset, diabetes duration, and established and novel risk factors
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College London, Royal Free Campus, London NW3 2PF, England
    Arch Intern Med 171:404-10. 2011
    ..We have examined the influence of age at onset and duration on the impact of diabetes mellitus on cardiovascular disease risk and all cause-mortality among men aged 60 to 79 years...
  82. pmc Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation
    S Goya Wannamethee
    Department of Primary Care and Population Health, University College Medical School, London, U K
    Diabetes Care 33:1990-6. 2010
    ..We prospectively examined the relationship between lung function and risk of type-2 diabetes and fatal and nonfatal coronary heart disease (CHD) events and investigated the hypothesis that inflammation may underlie these associations...
  83. pmc Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke
    Barbara J Jefferis
    UCL Department Primary Care and Population Health, Royal Free and University College Medical School, London, UK
    Atherosclerosis 205:302-8. 2009
    ....
  84. pmc Is the recent rise in type 2 diabetes incidence from 1984 to 2007 explained by the trend in increasing BMI?: evidence from a prospective study of British men
    Sarah L Hardoon
    Division of Population Health, University College London, London, UK
    Diabetes Care 33:1494-6. 2010
    ..To estimate the extent to which increasing BMI may explain the rise in type 2 diabetes incidence in British men from 1984 to 2007...
  85. pmc Assessing the impact of medication use on trends in major coronary risk factors in older British men: a cohort study
    Sarah L Hardoon
    Department of Primary Care and Population Health, Division of Population Health, UCL, London, UK
    Eur J Cardiovasc Prev Rehabil 17:502-8. 2010
    ..To investigate the role of medication in 20-year trends in blood pressure (BP) and blood lipids in older British men...
  86. pmc Changes in environmental tobacco smoke (ETS) exposure over a 20-year period: cross-sectional and longitudinal analyses
    Barbara J Jefferis
    British Regional Heart Study, UCL Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Addiction 104:496-503. 2009
    ..To examine long-term changes in environmental tobacco smoke (ETS) exposure in British men between 1978 and 2000, using serum cotinine...
  87. pmc How much of the recent decline in the incidence of myocardial infarction in British men can be explained by changes in cardiovascular risk factors? Evidence from a prospective population-based study
    Sarah L Hardoon
    Department of Primary Care and Population Sciences, UCL, London, United Kingdom
    Circulation 117:598-604. 2008
    ..The incidence of myocardial infarction (MI) in Britain has fallen markedly in recent years. Few studies have investigated the extent to which this decline can be explained by concurrent changes in major cardiovascular risk factors...
  88. ncbi Relationships of inflammatory and haemostatic markers with social class: results from a population-based study of older men
    Sheena Ramsay
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Atherosclerosis 197:654-61. 2008
    ..The effect of socio-economic gradient on the factor VIII-vWF complex, APC resistance, plasma viscosity and platelet count merits further study...
  89. doi Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies
    Naveed Sattar
    Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Lancet 371:1927-35. 2008
    ..We investigated to what extent metabolic syndrome and its individual components were related to risk for these two diseases in elderly populations...
  90. ncbi Alcohol, coronary heart disease and stroke: an examination of the J-shaped curve
    S G Wannamethee
    Department of Primary Care and Population Sciences, Royal Free Hospital School of Medicine, London, UK
    Neuroepidemiology 17:288-95. 1998
    ..The public health message should emphasise the potential harm of heavier drinking rather than concentrating on the possible benefits of light drinking...
  91. ncbi Effects of older age on fibrin D-dimer, C-reactive protein, and other hemostatic and inflammatory variables in men aged 60-79 years
    A Rumley
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Royal Infirmary, 10 Alexandra Parade, Glasgow, UK
    J Thromb Haemost 4:982-7. 2006
    ..However, there is a lack of data from large population studies for reliable estimates of reference ranges...
  92. pmc Physical activity and risk of cancer in middle-aged men
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, NW3 2PF, UK
    Br J Cancer 85:1311-6. 2001
    ..Moderately-vigorous or vigorous levels involving sporting activities are required to achieve such benefit...
  93. ncbi Physical activity and the prevention of stroke
    S G Wannamethee
    Department of Primary Care and Population Science, Royal Free and University College Medical School, London, UK
    J Cardiovasc Risk 6:213-6. 1999
    ..Sporting (vigorous) activity does not appear to be essential to achieve this benefit. Moderate levels of physical activity may be sufficient to achieve a significant reduction in stroke risk and overall cardiovascular risk...
  94. ncbi Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart St
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 107:1260-4. 2003
    ..Parity is associated with coronary heart disease (CHD) risk. In the present study, we assessed the associations between number of children and CHD in both women and men...