W Hamish B Wallace
Affiliation: University of Edinburgh
- Livebirth after cryopreserved ovarian tissue autotransplantationW Hamish B Wallace
Lancet 364:2093-4. 2004
- Fertility preservation for young patients with cancer: who is at risk and what can be offered?W Hamish B Wallace
Department of Child Life and Health, Division of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, UK
Lancet Oncol 6:209-18. 2005....
- Predicting age of ovarian failure after radiation to a field that includes the ovariesW Hamish B Wallace
Section of Child Life and Health, Department of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom
Int J Radiat Oncol Biol Phys 62:738-44. 2005..To predict the age at which ovarian failure is likely to develop after radiation to a field that includes the ovary in women treated for cancer...
- Male fertility following childhood cancer: current concepts and future therapiesMark F H Brougham
Royal Hospital for Sick Children, 17 Millerfield Place, Edinburgh, EH9 1LW, UK
Asian J Androl 5:325-37. 2003....
- Late reproductive sequelae following treatment of childhood cancer and options for fertility preservationAngela B Thomson
Department of Haematology Oncology, Royal Hospital for Sick Children, 17 Millerfield Place, Edinburgh, EH9 1LW, UK
Best Pract Res Clin Endocrinol Metab 16:311-34. 2002..In this chapter we consider the late reproductive sequelae following treatment for childhood cancer and options for fertility preservation...
- Antimüllerian hormone, the assessment of the ovarian reserve, and the reproductive outcome of the young patient with cancerRichard A Anderson
Medical Research Council Centre for Reproductive Health, University of Edinburgh, Edinburgh, United Kingdom
Fertil Steril 99:1469-75. 2013..These therapies can adversely impact all aspects of female reproduction, including hypothalamic, pituitary, and ovarian hormonal activity, and the ability of the uterus to support a successful pregnancy...
- Do doctors discuss fertility issues before they treat young patients with cancer?Richard A Anderson
Division of Developmental and Reproductive Science, University of Edinburgh, Edinburgh, UK
Hum Reprod 23:2246-51. 2008..We have assessed UK practice relating to information provision about the effects of cancer treatment on fertility and options for fertility preservation...
- Physiological versus standard sex steroid replacement in young women with premature ovarian failure: effects on bone mass acquisition and turnoverPatricia M Crofton
Department of Paediatric Biochemistry, The Royal Hospital for Sick Children, Edinburgh, Scotland, UK
Clin Endocrinol (Oxf) 73:707-14. 2010..The aim of this exploratory study was to establish whether we could improve skeletal health with a physiological regimen of SSR in young women with premature ovarian failure (POF)...
- Oncofertility and preservation of reproductive capacity in children and young adultsW Hamish B Wallace
Department of Pediatric Haematology Oncology, Royal Hospital for Sick Children, Edinburgh, Scotland, United Kingdom
Cancer 117:2301-10. 2011..For prepubertal girls, ovarian tissue cryopreservation should be considered if the risk of premature menopause is high, but for the prepubertal boy there are no established techniques in current practice...
- Diethylstilboestrol exposure does not reduce testosterone production in human fetal testis xenograftsRod T Mitchell
MRC Centre for Reproductive Health, Edinburgh University, Edinburgh, Scotland, UK
PLoS ONE 8:e61726. 2013..This indicates that DES exposure is likely to pose minimal risk to masculinization of the human fetus...
- Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancerRobert J Johnston
Royal Hospital for Sick Children, Edinburgh, Scotland, United Kingdom
Pediatr Blood Cancer 53:296-302. 2009..We discuss the physiology of normal ovarian function, the effects of cancer treatments on ovarian function and the techniques for evaluation of ovarian reserve in survivors of childhood cancer...
- Radiation damage to the uterus -- review of the effects of treatment of childhood cancerHilary O D Critchley
Section of Obstetrics and Gynaecology, Department of Reproductive and Developmental Sciences, Centre for Reproductive Biology, University of Edinburgh, 37 Chalmers Street, Edinburgh EH3 9ET, UK
Hum Fertil (Camb) 5:61-6. 2002..The uterine factor remains a concern and women who are survivors of childhood cancer and their carers must recognize that these pregnancies will be at high risk...
- Semen quality and spermatozoal DNA integrity in survivors of childhood cancer: a case-control studyAngela B Thomson
Section of Child Life and Health, Department of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, UK
Lancet 360:361-7. 2002..Our aim was to assess testicular function in survivors of childhood cancer...
- Fertility preservation in girls and young womenRichard A Anderson
Division of Reproductive and Developmental Science, MRC Centre for Reproductive Health, Queens Medical Research Institute, University of Edinburgh, Edinburgh, UK
Clin Endocrinol (Oxf) 75:409-19. 2011..Effective approaches for prepubertal boys are also required...
- A validated model of serum anti-müllerian hormone from conception to menopauseThomas W Kelsey
School of Computer Science, University of St Andrews, St Andrews, Scotland, United Kingdom
PLoS ONE 6:e22024. 2011..e. the ovarian reserve, and be of value in predicting reproductive lifespan. A full description of AMH production up to the menopause has not been previously reported...
- Bone Turnover and Growth during and after Chemotherapy in Children with Solid TumorsLouise F Bath
Section of Child Life and Health, Department of Reproductive and Developmental Sciences, 20 Sylvan Place, Edinburgh EH9 IUW, Scotland
Pediatr Res 55:224-30. 2004..BALP remained suppressed throughout treatment (p < 0.001). Intense courses of treatment for solid tumors have a direct suppressive effect on bone turnover, with an imbalance between collagen synthesis and degradation...
- Cardiovascular effects of physiological and standard sex steroid replacement regimens in premature ovarian failureJeremy P Langrish
Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, EH16 4SA United Kingdom
Hypertension 53:805-11. 2009..These findings have major implications for the future cardiovascular health of young women who require long-term sex steroid replacement therapy...
- Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiationRod T Mitchell
MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
Hum Reprod 25:2405-14. 2010..Studies of human fetal testis development are hampered by the lack of appropriate model, and intervention systems. We hypothesized that human fetal testis xenografts can recapitulate normal development...
- Pregnancy in women who had cancer in childhoodAngela B Edgar
Department of Oncology, Royal Hospital for Sick Children, Edinburgh, UK
Eur J Cancer 43:1890-4. 2007..A number of large multi-centre studies, are underway and will provide new insights into pregnancy outcomes in survivors of childhood cancer...
- The late endocrine effects of childhood cancer treatmentMark F H Brougham
Department of Paediatric Haematology and Oncology, Royal Hospital for Sick Children, 17 Millerfield Place, Edinburgh, EH9 1LW, UK
Pediatr Rehabil 5:191-201. 2002....
- Ovarian volume correlates strongly with the number of nongrowing follicles in the human ovaryThomas W Kelsey
School of Computer Science, University of St Andrews, St Andrews, Scotland, Kelsey KY16 9SX, UK
Obstet Gynecol Int 2012:305025. 2012..These strong correlations indicate that ovarian volume is a useful factor in the indirect estimation of human ovarian reserve for the individual woman...
- Human ovarian reserve from conception to the menopauseW Hamish B Wallace
Department of Reproductive and Developmental Sciences, Division of Child Life and Health, University of Edinburgh, Edinburgh, United Kingdom
PLoS ONE 5:e8772. 2010..An increased understanding of the dynamics of human ovarian reserve will provide a more scientific basis for fertility counselling for both healthy women and those who have survived gonadotoxic cancer treatments...
- Late effects of the treatment of childhood cancer on the female reproductive system and the potential for fertility preservationLouise E Bath
Department of Developmental and Reproductive Sciences, University of Edinburgh, UK
BJOG 109:107-14. 2002
- Long-term follow-up of people who have survived cancer during childhoodRoderick Skinner
Department of Paediatric and Adolescent Oncology, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK
Lancet Oncol 7:489-98. 2006..This review discusses the present provision of long-term follow-up, and summarises information that might facilitate design and implementation of future models of long-term follow-up care...
- Female reproductive potential post-treatment for childhood cancerKevin A Burton
Department of Obstetrics and Gynaecology, Glasgow Royal Infirmary, Glasgow
Hosp Med 63:522-7. 2002..Hence female reproductive potential following treatment must be addressed. Issues concerning subsequent uterine and ovarian function, fertility options and importantly the ethics and safety of treatment approaches are discussed herein...
- Long-term follow-up of children treated for cancer: why is it necessary, by whom, where and how?Roderick Skinner
Department of Paediatric and Adolescent Oncology, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
Arch Dis Child 92:257-60. 2007..It is of paramount importance to ascertain and meet the needs of survivors themselves...
- Long-term follow-up of pediatric cancer survivors: education, surveillance, and screeningWendy Landier
City of Hope Comprehensive Cancer Center, Duarte, California, USA
Pediatr Blood Cancer 46:149-58. 2006....
- Barriers to follow-up care of survivors in the United States and the United KingdomKevin C Oeffinger
Department of Pediatrics and Internal Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Pediatr Blood Cancer 46:135-42. 2006..Potential barriers in both cultures and health care environments are described. A better understanding of these barriers has led to the development and testing of interventions intended to optimize the health care of survivors...
- Long-term follow-up of survivors of childhood cancer in the UKAliki Taylor
Department of Public Health and Epidemiology, The University of Birmingham, Edgbaston, Birmingham, United Kingdom
Pediatr Blood Cancer 42:161-8. 2004..The aim of this study was to quantify the long-term clinical follow-up practices concerning survivors of childhood cancer...
- Follow-up after childhood cancer: evaluation of a three-level modelChristine Eiser
Department of Psychology, University of Sheffield, Western Bank, and Academic Unit of Clinical Oncology, Cancer Research Centre, Weston Park Hospital, Sheffield S10 2TP, United Kingdom
Eur J Cancer 42:3186-90. 2006..Developing strategies for the long term follow-up of survivors of childhood cancer. BMJ 2001;323:271-274]...