Wallace H. The polyamines: past, present and future. Essays Biochem. 2009;46:1-9 pubmed publisher
Ubah O, Wallace H. Cancer therapy: Targeting mitochondria and other sub-cellular organelles. Curr Pharm Des. 2014;20:201-22 pubmed
..In this review, we summarise the roles of these cellular organelles in tumour initiation and establishment as well as current trends in development of agents that target deregulations in these organelles. ..
Penny L, Wallace H. The challenges for cancer chemoprevention. Chem Soc Rev. 2015;44:8836-47 pubmed publisher
..This approach will involve multidisciplinary teams of healthcare providers and scientists with the big challenge particularly for medicinal chemists being to design and synthesise the ideal chemopreventative agent. ..
Li J, Cameron G, Wallace H. Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells. Amino Acids. 2016;48:1003-12 pubmed publisher
Wallace H, Fraser A, Hughes A. A perspective of polyamine metabolism. Biochem J. 2003;376:1-14 pubmed
..The future will be in adopting a functional genomics approach to identifying polyamine-regulated genes linked to either carcinogenesis or apoptosis. ..
Damiani E, Wallace H. Polyamines and Cancer. Methods Mol Biol. 2018;1694:469-488 pubmed publisher
..The last section concentrates on chemoprevention, where the different strategies that have been undertaken to interfere with polyamine metabolism and function for antiproliferative intervention are outlined and discussed. ..