Affiliation: University of Surrey
- The significance of excursions above the ADI: duration in relation to pivotal studiesR Walker
School of Biological Sciences, University of Surrey, Guildford, United Kingdom
Regul Toxicol Pharmacol 30:S114-8. 1999....
- The significance of excursions above the ADI. Case study: monosodium glutamateR Walker
University of Surrey, School of Biological Sciences, Guildford, Surrey, United Kingdom
Regul Toxicol Pharmacol 30:S119-21. 1999....
- Criteria for risk assessment of botanical food supplementsR Walker
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, GU2 7XH, Surrey, UK
Toxicol Lett 149:187-95. 2004..Human studies of efficacy and possible side effects may help in determining the acceptable margin of exposure. A decision tree will be presented to assist in determining the extent of data requirements based on the nature of the product...
- Hazard characterisation of chemicals in food and diet. dose response, mechanisms and extrapolation issuesE Dybing
National Institute of Public Health, Department of Environmental Medicine, PO Box 4404 Nydalen, N 0403, Oslo, Norway
Food Chem Toxicol 40:237-82. 2002..Macronutrients and whole foods must be evaluated on a case-by-case basis and cannot follow a routine assessment protocol...
- Risk characterisation of chemicals in food and dietA G Renwick
University of Southampton, Clinical Pharmacology Group, School of Medicine, Biomedical Sciences Building, Bassett Crescent East, SO16 7PX, Southampton, UK
Food Chem Toxicol 41:1211-71. 2003
- Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplementsB Schilter
Nestle, Nestle Research Centre, PO Box 44, Vers chez les Blanc, CH 1000 Lausanne 26, Switzerland
Food Chem Toxicol 41:1625-49. 2003....
- Safety issues of botanicals and botanical preparations in functional foodsR Kroes
Institute for Risk Assessment Sciences IRAS, Utrecht University, P O Box 80176, NL 3508 TD Utrecht, The Netherlands
Toxicology 198:213-20. 2004..This guidance tool in safety assessment was developed by an expert group of the International Life Sciences Institute (ILSI), European Branch, and is currently in press. In this paper a summarised version of this tool is presented...
- Risk assessment of micronutrientsA G Renwick
School of Medicine, Faculty of Medicine, Health and Life Sciences, University of Southampton, Southampton SO16 7PX, UK
Toxicol Lett 180:123-30. 2008..Risk-benefit approaches have been developed recently that balance the risk of toxicity against the risk of deficiency, and offer the potential for more scientifically based methods...