Affiliation: University of Surrey
- The significance of excursions above the ADI: duration in relation to pivotal studiesR Walker
School of Biological Sciences, University of Surrey, Guildford, United Kingdom
Regul Toxicol Pharmacol 30:S114-8. 1999....
- The significance of excursions above the ADI. Case study: monosodium glutamateR Walker
University of Surrey, School of Biological Sciences, Guildford, Surrey, United Kingdom
Regul Toxicol Pharmacol 30:S119-21. 1999....
- Criteria for risk assessment of botanical food supplementsR Walker
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, GU2 7XH, Surrey, UK
Toxicol Lett 149:187-95. 2004..Human studies of efficacy and possible side effects may help in determining the acceptable margin of exposure. A decision tree will be presented to assist in determining the extent of data requirements based on the nature of the product...
- Hazard characterisation of chemicals in food and diet. dose response, mechanisms and extrapolation issuesE Dybing
National Institute of Public Health, Department of Environmental Medicine, PO Box 4404 Nydalen, N-0403, Oslo, Norway
Food Chem Toxicol 40:237-82. 2002..Macronutrients and whole foods must be evaluated on a case-by-case basis and cannot follow a routine assessment protocol...
- Risk characterisation of chemicals in food and dietA G Renwick
University of Southampton, Clinical Pharmacology Group, School of Medicine, Biomedical Sciences Building, Bassett Crescent East, SO16 7PX, Southampton, UK
Food Chem Toxicol 41:1211-71. 2003
- Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplementsB Schilter
Nestl, , PO Box 44, Vers-chez-les-Blanc, CH-1000 Lausanne 26, Switzerland
Food Chem Toxicol 41:1625-49. 2003....
- Safety issues of botanicals and botanical preparations in functional foodsR Kroes
Institute for Risk Assessment Sciences IRAS, Utrecht University, P O Box 80176, NL 3508 TD Utrecht, The Netherlands
Toxicology 198:213-20. 2004..This guidance tool in safety assessment was developed by an expert group of the International Life Sciences Institute (ILSI), European Branch, and is currently in press. In this paper a summarised version of this tool is presented...
- Risk assessment of micronutrientsA G Renwick
School of Medicine, Faculty of Medicine, Health and Life Sciences, University of Southampton, Southampton SO16 7PX, UK
Toxicol Lett 180:123-30. 2008..Risk-benefit approaches have been developed recently that balance the risk of toxicity against the risk of deficiency, and offer the potential for more scientifically based methods...