Research Topics
| A F WalkerSummaryAffiliation: University of Reading Country: UK Publications
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Detail Information
Publications
Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trialAnn F Walker
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading
Br J Gen Pract 56:437-43. 2006..Hawthorn (Crataegus laevigata) leaves, flowers and berries are used by herbal practitioners in the UK to treat hypertension in conjunction with prescribed drugs. Small-scale human studies support this approach...
Herbal medicine: the science of the artAnn F Walker
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading RG6 6AP, UK
Proc Nutr Soc 65:145-52. 2006..Strategies for investigating the full holistic approach of phytotherapy and its main elements are discussed and illustrated through the author's studies at the University of Reading...
Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adultsA F Walker
Hugh Sinclair Unit of Human Nutrition, The University of Reading, UK
Phytomedicine 9:681-6. 2002..Double blind, placebo-controlled studies are now warranted to confirm these results...
Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind studyAnn F Walker
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Whiteknights, Reading, UK
Magnes Res 16:183-91. 2003..Mg oxide supplementation resulted in no differences compared to placebo. We conclude that a daily supplementation with Mg citrate shows superior bioavailability after 60 days of treatment when compared with other treatments studied...
Flavonoids--a new direction for the treatment of fluid retention?S Christie
Hugh Sinclair Unit of Human Nutrition, The University of Reading, Reading RG6 6AP, UK
Phytother Res 15:467-75. 2001..This paper marshals available data including some preliminary studies that suggest that detailed scientific study of this clinical area and its treatment through flavonoid intervention is warranted...
Artichoke leaf extract reduces symptoms of irritable bowel syndrome in a post-marketing surveillance studyA F Walker
The Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, PO Box 226, Whiteknights, Reading RG6 6AP, UK
Phytother Res 15:58-61. 2001..These results provide support for the notion that ALE has potential value in relieving IBS symptoms and suggest that a controlled trial is justified...
Flavonoid supplement improves leg health and reduces fluid retention in pre-menopausal women in a double-blind, placebo-controlled studyS Christie
Hugh Sinclair Unit of Human Nutrition, The School of Biosciences, The University of Reading, Reading, UK
Phytomedicine 11:11-7. 2004..066). We conclude that flavonoids supplements may provide a new therapeutic direction to counter premenstrual fluid retention and improve leg health. A larger study is now warranted...
The significance of "nonsignificance" in randomized controlled studies: a discussion inspired by a double-blinded study on St. John's wort (Hypericum perforatum L.) for premenstrual symptomsStephen M Hicks
Hugh Sinclair Unit of Human Nutrition, The School of Food Biosciences, The University of Reading, Reading RG6 6AP, UK
J Altern Complement Med 10:925-32. 2004..Following this discussion the recommendation is made that, in future, similar studies should be powered to detect a minimum clinically relevant difference between treatments...
Artichoke leaf extract reduces symptoms of irritable bowel syndrome and improves quality of life in otherwise healthy volunteers suffering from concomitant dyspepsia: a subset analysisRafe Bundy
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading, UK
J Altern Complement Med 10:667-9. 2004..Does artichoke leaf extract (ALE) ameliorate symptoms of Irritable bowel syndrome (IBS) in otherwise healthy volunteers suffering concomitant dyspepsia?..
Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot studyRafe Bundy
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading, UK
J Altern Complement Med 10:1015-8. 2004..To assess the effects of turmeric (Curcuma longa) extract on irritable bowel syndrome (IBS) symptomology in otherwise healthy adults...
Unexpected benefit of sorbitol placebo in Mg intervention study of premenstrual symptoms: implications for choice of placebo in RCTsAnn F Walker
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, PO Box 226, Reading RG6 6AP, UK
Med Hypotheses 58:213-20. 2002..It appears that sorbitol may influence Mg homeostasis in women suffering premenstrual symptoms, but not in healthy individuals. Implications for placebo choice in RCTs are discussed...
Promising hypotensive effect of hawthorn extract: a randomized double-blind pilot study of mild, essential hypertensionAnn F Walker
Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Whiteknights, PO Box 226, Reading RG6 6AP, UK
Phytother Res 16:48-54. 2002..094) was also observed in those taking hawthorn compared with the other groups. These findings warrant further study, particularly in view of the low dose of hawthorn extract used...
Artichoke leaf extract reduces mild dyspepsia in an open studyG Marakis
Hugh Sinclair Unit of Human Nutrition, The University of Reading, UK
Phytomedicine 9:694-9. 2002..We conclude that ALE shows promise to ameliorate upper gastro-intestinal symptoms and improve quality of life in otherwise healthy subjects suffering from dyspepsia...
Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trialRafe Bundy
Hugh Sinclair Unit of Human Nutrition, School of Chemistry, Food Biosciences and Pharmacy, The University of Reading, Reading, UK
Phytomedicine 15:668-75. 2008..In comparison with a previous trial, it is suggested that the apparent positive health status of the study population may have contributed to the modesty of the observed response...
Improved arthritic knee health in a pilot RCT of phytotherapyLouise Hamblin
Battersea Research Group, Wandsworth Primary Care Trust, Bolingbroke Hospital, London SW11 6HN, UK
J R Soc Promot Health 128:255-62. 2008..008) compared with baseline for the active, but not for the placebo group. This pilot study showed that herbal medicine prescribed for the individual by a herbal practitioner resulted in improvement of symptoms of OA of the knee...
