Research Topics

Milène Volpato

Affiliation: University of Bradford

Country: UK

Tailoring targeted therapy to individual patients: lessons to be learnt from the development of mitomycin C
Milène Volpato
Institute of Cancer Therapeutics, University of Bradford, Bradford BD7 1DP, UK
Cancer Genomics Proteomics 4:175-86. 2007
Chemical synthesis and biological evaluation of a NAD(P)H:quinone oxidoreductase-1 targeted tripartite quinone drug delivery system
Milène Volpato
Institute of Cancer Therapeutics, University of Bradford, Bradford BD7 1DP, United Kingdom
Mol Cancer Ther 6:3122-30. 2007
Formation of DNA interstrand cross-links as a marker of Mitomycin C bioreductive activation and chemosensitivity
Milène Volpato
Cancer Research Unit, Tom Connors Cancer Research Centre, University of Bradford, Bradford BD7 1DP, UK
Eur J Cancer 41:1331-8. 2005

Tailoring targeted therapy to individual patients: lessons to be learnt from the development of mitomycin C
Milène Volpato
Institute of Cancer Therapeutics, University of Bradford, Bradford BD7 1DP, UK
Cancer Genomics Proteomics 4:175-86. 2007
....
Chemical synthesis and biological evaluation of a NAD(P)H:quinone oxidoreductase-1 targeted tripartite quinone drug delivery system
Milène Volpato
Institute of Cancer Therapeutics, University of Bradford, Bradford BD7 1DP, United Kingdom
Mol Cancer Ther 6:3122-30. 2007
..Further development of this concept to fine-tune substrate specificity for specific reductases and/or the inclusion of alternative therapeutic agents is warranted...
Formation of DNA interstrand cross-links as a marker of Mitomycin C bioreductive activation and chemosensitivity
Milène Volpato
Cancer Research Unit, Tom Connors Cancer Research Centre, University of Bradford, Bradford BD7 1DP, UK
Eur J Cancer 41:1331-8. 2005
..Further studies are required to assess whether this approach as a mean of prediction has practical applications in vivo...