F Vollrath

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Biological liquid crystal elastomers
    David P Knight
    Zoology Department, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Philos Trans R Soc Lond B Biol Sci 357:155-63. 2002
  2. ncbi request reprint Spiders' webs
    Fritz Vollrath
    Department of Zoology, University of Oxford, UK
    Curr Biol 15:R364-5. 2005
  3. pmc Chitin in the silk gland ducts of the spider Nephila edulis and the silkworm Bombyx mori
    Gwilym J G Davies
    Department of Zoology, The University of Oxford, South Parks Road, Oxford, United Kingdom
    PLoS ONE 8:e73225. 2013
  4. doi request reprint Consequences of electrical conductivity in an orb spider's capture web
    Fritz Vollrath
    Department of Zoology, South Parks Road, Oxford, OXI 3PS, UK
    Naturwissenschaften 100:1163-9. 2013
  5. ncbi request reprint African bees to control African elephants
    Fritz Vollrath
    Mpala Research Centre, Nanyuki, Box 555, Kenya
    Naturwissenschaften 89:508-11. 2002
  6. ncbi request reprint Strength and structure of spiders' silks
    F Vollrath
    J Biotechnol 74:67-83. 2000
  7. pmc The effect of spinning conditions on the mechanics of a spider's dragline silk
    F Vollrath
    Department of Zoology, Universitetsparken B135, 8000 Aarhus C, Denmark
    Proc Biol Sci 268:2339-46. 2001
  8. ncbi request reprint Liquid crystalline spinning of spider silk
    F Vollrath
    Zoology Department, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nature 410:541-8. 2001
  9. ncbi request reprint Comparing the rheology of native spider and silkworm spinning dope
    C Holland
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nat Mater 5:870-4. 2006
  10. doi request reprint Comparing the rheology of mulberry and "wild" silkworm spinning dopes
    C Holland
    Department of Zoology, The University of Oxford, South Parks Road, Oxford, OX1 3PS, UK
    Biopolymers 97:362-7. 2012

Collaborators

Detail Information

Publications59

  1. pmc Biological liquid crystal elastomers
    David P Knight
    Zoology Department, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Philos Trans R Soc Lond B Biol Sci 357:155-63. 2002
    ..In this paper, the possibility that other transversely banded fibrillar proteins are also LCEs is discussed...
  2. ncbi request reprint Spiders' webs
    Fritz Vollrath
    Department of Zoology, University of Oxford, UK
    Curr Biol 15:R364-5. 2005
  3. pmc Chitin in the silk gland ducts of the spider Nephila edulis and the silkworm Bombyx mori
    Gwilym J G Davies
    Department of Zoology, The University of Oxford, South Parks Road, Oxford, United Kingdom
    PLoS ONE 8:e73225. 2013
    ..We conclude that chitin may well be an essential component for the construction of spinning ducts; we further conclude that in both species chitin may indicate the evolutionary origin of the spinning ducts. ..
  4. doi request reprint Consequences of electrical conductivity in an orb spider's capture web
    Fritz Vollrath
    Department of Zoology, South Parks Road, Oxford, OXI 3PS, UK
    Naturwissenschaften 100:1163-9. 2013
    ..Finally, we examine the hypothesis that such distortion could be used by potential prey to detect the presence of a web but conclude that any effect would probably be too small to allow an insect to take evasive action. ..
  5. ncbi request reprint African bees to control African elephants
    Fritz Vollrath
    Mpala Research Centre, Nanyuki, Box 555, Kenya
    Naturwissenschaften 89:508-11. 2002
    ..We argue that bees can be employed profitably to protect not only selected trees, but also selected areas, from elephant damage...
  6. ncbi request reprint Strength and structure of spiders' silks
    F Vollrath
    J Biotechnol 74:67-83. 2000
    ....
  7. pmc The effect of spinning conditions on the mechanics of a spider's dragline silk
    F Vollrath
    Department of Zoology, Universitetsparken B135, 8000 Aarhus C, Denmark
    Proc Biol Sci 268:2339-46. 2001
    ..We argue that both trade-offs (between mechanical properties) and constraints (in the manufacturing process) have a large role in defining spider silk fibres...
  8. ncbi request reprint Liquid crystalline spinning of spider silk
    F Vollrath
    Zoology Department, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nature 410:541-8. 2001
    ....
  9. ncbi request reprint Comparing the rheology of native spider and silkworm spinning dope
    C Holland
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nat Mater 5:870-4. 2006
    ..This observation opens the door to using polymer theory to clarify our general understanding of natural silks, despite the many specializations found in different animal species...
  10. doi request reprint Comparing the rheology of mulberry and "wild" silkworm spinning dopes
    C Holland
    Department of Zoology, The University of Oxford, South Parks Road, Oxford, OX1 3PS, UK
    Biopolymers 97:362-7. 2012
    ..postica seems to balance both. We conclude that comparative studies provide valuable baseline information for future biomimetic applications and modeling, as well as illuminating biologically important details of silk processing...
  11. ncbi request reprint Rheological characterization of nephila spidroin solution
    Xin Chen
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Biomacromolecules 3:644-8. 2002
    ....
  12. ncbi request reprint Changes in element composition along the spinning duct in a Nephila spider
    D P Knight
    Zoology Department, University of Oxford, UK
    Naturwissenschaften 88:179-82. 2001
    ..Thus precise control of the ionic environment within the spider's spinning duct may be important in forming a tough insoluble thread and when devising mimetic processes to spin silk proteins industrially...
  13. doi request reprint Comparing normal and torn rotator cuff tendons using dynamic shear analysis
    S Chaudhury
    Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford OX3 0BA, UK
    J Bone Joint Surg Br 93:942-8. 2011
    ..This pilot study provides some insight into mechanisms that might contribute to the failure of repair surgery, and with future application could help direct the most appropriate treatment for specific rotator cuff tears...
  14. ncbi request reprint Predicting the mechanical properties of spider silk as a model nanostructured polymer
    D Porter
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Eur Phys J E Soft Matter 16:199-206. 2005
    ..Thus, we can demonstrate an inherent simplicity at a macromolecular level in the design principles of natural materials. This surprising observation allows in depth comparison of natural with man-made materials...
  15. ncbi request reprint Comparison of the spinning of selachian egg case ply sheets and orb web spider dragline filaments
    D P Knight
    Department of Zoology, Oxford University, South Parks Road, Oxford OX1 3PS, UK
    Biomacromolecules 2:323-34. 2001
    ..The most important difference is that spiders produce a tough material by unfolding and hydrogen-bonding their silk dope molecules while Selachian fish do it by covalently cross-linking the molecules without unfolding them...
  16. ncbi request reprint Structure and function of the silk production pathway in the spider Nephila edulis
    F Vollrath
    Department of Zoology, Aarhus University, Aarhus C, Denmark
    Int J Biol Macromol 24:243-9. 1999
    ..Together, these observations indicate that the spider silk production pathway is highly optimised for the production of silk threads and shows considerable biomimetic potential...
  17. ncbi request reprint Beta transition and stress-induced phase separation in the spinning of spider dragline silk
    D P Knight
    Department of Zoology, South Parks Road, OX1 3PS, Oxford, UK
    Int J Biol Macromol 27:205-10. 2000
    ..Measurements of draw stress at different draw rates during silking confirm that a stress-induced phase transition occurs...
  18. doi request reprint Rheo-attenuated total reflectance infrared spectroscopy: a new tool to study biopolymers
    Maxime Boulet-Audet
    University of Oxford, Department of Zoology, Tinbergen Building, Oxford, OX1 3PS, UK
    Phys Chem Chem Phys 13:3979-84. 2011
    ..We propose that this tool will provide further insight into not only silk but any biopolymer solution, opening a new window into biological materials...
  19. ncbi request reprint Structural disorder in silk proteins reveals the emergence of elastomericity
    Cedric Dicko
    Department of Zoology, Oxford University, OX1 3PS, UK
    Biomacromolecules 9:216-21. 2008
    ..Taken together, our biophysical and evolutionary findings reveal that silk elastomericity evolved in tandem with specializations in the process of silk spinning...
  20. ncbi request reprint Secondary structures and conformational changes in flagelliform, cylindrical, major, and minor ampullate silk proteins. Temperature and concentration effects
    Cedric Dicko
    Department of Zoology, Oxford University, Oxford OX1 3PS, United Kingdom
    Biomacromolecules 5:2105-15. 2004
    ..We discuss the implication of these results in the spinning process and a possible mechanism for temperature-induced beta-sheet formation...
  21. ncbi request reprint Structural conformation of spidroin in solution: a synchrotron radiation circular dichroism study
    Cedric Dicko
    Department of Zoology, Oxford University, OX1 3PS United Kingdom
    Biomacromolecules 5:758-67. 2004
    ..Specifically we analyze, in a series of example studies on structural transitions induced in liquid silk, the type of information accessible from this technique and any artifacts that might arise in studying self-assembling systems...
  22. ncbi request reprint Transition to a beta-sheet-rich structure in spidroin in vitro: the effects of pH and cations
    Cedric Dicko
    Department of Zoology, Oxford University, UK
    Biochemistry 43:14080-7. 2004
    ..We discuss the importance of these findings for the spinning process and the active role played by the spider to alter the kinetics of the transition...
  23. pmc Bee threat elicits alarm call in African elephants
    Lucy E King
    Animal Behaviour Research Group, Department of Zoology, University of Oxford, Oxford, UK
    PLoS ONE 5:e10346. 2010
    ..This suggests that these elephant rumbles may function as referential signals, in which a formant frequency shift alerts nearby elephants about an external threat, in this case, the threat of bees...
  24. ncbi request reprint Conformational polymorphism, stability and aggregation in spider dragline silks proteins
    Cedric Dicko
    Department of Zoology, Oxford University, Oxford OX1 3PS, UK
    Int J Biol Macromol 36:215-24. 2005
    ..Changing the solvent polarity showed that HFIP and TFE induced formation of stable helical forms whereas MeOH, EtOH and IsoP induced a kinetically driven formation of beta-sheet rich structure...
  25. doi request reprint Structure and function of the major ampullate spinning duct of the golden orb weaver, Nephila edulis
    G J G Davies
    Department of Zoology, The University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Tissue Cell 45:306-11. 2013
    ..This suggests constancy in the region where the nascent silk filament is drawn down within the lumen of the duct, which is likely to be fundamental for forming strong and tough fibres. ..
  26. ncbi request reprint Biology of spider silk
    F Vollrath
    Department of Zoology, University of Aarhus, Aarhus C, Denmark
    Int J Biol Macromol 24:81-8. 1999
    ..An argument can be made that silk is optimised for a wide range of conditions rather than maximised for strength or toughness. Moreover, it seems that the spider is able to induce rapid and temporary adaptations of silk properties...
  27. doi request reprint Elasticity of spider silks
    Yi Liu
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, United Kingdom
    Biomacromolecules 9:1782-6. 2008
    ..Our study corroborates the view that proline-containing motifs contribute to the elasticity of not only spider silks, but also other bioelastomers...
  28. ncbi request reprint Optimal area use in orb webs of the spider Araneus diadematus
    T Krink
    Department of Computer Science, Aarhus University, Ny Munkegade B 540, 8000 Aarhus C, Denmark
    Naturwissenschaften 87:90-3. 2000
    ..Since in very narrow frames the spider adjusted the auxiliary to suit the subsequent capture spiral, we suggest that an initial spatial survey led to the final adaptation of overall web geometry to a web site...
  29. ncbi request reprint Local tolerance to spider silks and protein polymers in vivo
    F Vollrath
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, England
    In Vivo 16:229-34. 2002
    ..Furthermore, the histopathological images recorded after 14 days revealed no marked differences between the dressings. Polyurethane films, however, seemed to be superior with respect to the duration of the wound healing process...
  30. ncbi request reprint Spider silk: thousands of nano-filaments and dollops of sticky glue
    Fritz Vollrath
    Department of Zoology, South Parks Road, Oxford OX1 3PS, UK
    Curr Biol 16:R925-7. 2006
    ..Some spiders use glues while others deploy strands of fine filaments for fixing flies. Recent work has provided new insights into the mechanical properties of these nano-scale ropes...
  31. pmc Spinning an elastic ribbon of spider silk
    David P Knight
    Department of Zoology, University of Oxford, UK
    Philos Trans R Soc Lond B Biol Sci 357:219-27. 2002
    ..This is achieved by the combination of an initial internal draw down, well inside the duct, and a final draw down, after the silk has left the spigot. The spinning mechanism in Loxosceles may be more ancestral...
  32. ncbi request reprint pH induced changes in the rheology of silk fibroin solution from the middle division of Bombyx mori silkworm
    Ann E Terry
    Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS United Kingdom
    Biomacromolecules 5:768-72. 2004
    ..The solution could also be converted to sol from the gel state by the addition of EDTA. The possible mechanisms for gel formation in fibroin solutions is discussed as are the implications for the process of spinning silk fibers...
  33. ncbi request reprint Horses and cows might teach us about human knees
    C Holland
    Department of Zoology, University of Oxford, South Parks Road, Oxford, UK
    Naturwissenschaften 101:351-4. 2014
    ..We assert that this technique could provide a powerful new tool to precisely quantify the pathology of osteoarthritis for the medical field. ..
  34. doi request reprint Spider silk: super material or thin fibre?
    D Porter
    Department of Zoology, University of Oxford, Oxford, OX1 3PS, UK
    Adv Mater 25:1275-9. 2013
    ..Predictive structure-property relations are derived for strength and fracture toughness, and small diameter plays a large part in silk properties...
  35. doi request reprint Fourier transform infrared spectroscopic analysis of normal and torn rotator-cuff tendons
    S Chaudhury
    Department of Orthopaedics, Nuffield Orthopaedic Centre, University of Oxford, Oxford OX3 7LD, UK
    J Bone Joint Surg Br 93:370-7. 2011
    ..The approach described is rapid and has the potential to be used peri-operatively to determine the quality of the tendon and the extent of the disease, thus guiding surgical repair...
  36. pmc Breaking the 200 nm limit for routine flow linear dichroism measurements using UV synchrotron radiation
    Cedric Dicko
    Dept of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Biophys J 95:5974-7. 2008
    ..Spectra for calf thymus DNA, DNA/ethidium bromide, and DNA/4',6-diamidino-2-phenylindole systems illustrate the quality of data that can be obtained...
  37. ncbi request reprint Proline and processing of spider silks
    Yi Liu
    Department of Zoology, University of Oxford, South Parks Road, Oxford, OX1 3PS, United Kingdom
    Biomacromolecules 9:116-21. 2008
    ..Our results indicate how chemical compositions, coupled with processing conditions, shape the mechanical properties of the spider silk...
  38. ncbi request reprint The effects of neurotoxins on web-geometry and web-building behaviour in Araneus diadematus Cl
    Thomas Hesselberg
    Department of Zoology, Universitetsparken B135, 8000 Aarhus C, Denmark
    Physiol Behav 82:519-29. 2004
    ..Furthermore, caffeine caused webs to be rounder. Our observations suggest that these neurotoxins disturb different parts of the web-building programme presumably by affecting different actions in the spider's CNS...
  39. ncbi request reprint Biopolymers: shape memory in spider draglines
    Olivier Emile
    Laboratoire de Physique des Lasers, UMR CNRS 6627, Universite de Rennes 1, 35042 Rennes, France
    Nature 440:621. 2006
    ....
  40. ncbi request reprint Copper in the silk formation process of Bombyx mori silkworm
    Li Zhou
    Department of Macromolecular Science, The Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, PR China
    FEBS Lett 554:337-41. 2003
    ..Taken together these findings indicate that copper could play a role in the natural spinning process in silkworms...
  41. ncbi request reprint The conserved C-termini contribute to the properties of spider silk fibroins
    Alexander Sponner
    Institute of Molecular Biotechnology and Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstrasse 11, D 07745 Jena, Germany
    Biochem Biophys Res Commun 338:897-902. 2005
    ..Special sequence parts endow the C-termini with the capability to promote both the solubility and aggregation of the fibroins depending on the environmental conditions...
  42. ncbi request reprint Analyis of structure/property relationships in silkworm (Bombyx mori) and spider dragline (Nephila edulis) silks using Raman spectroscopy
    Jutarat Sirichaisit
    Manchester Materials Science Centre, UMIST University of Manchester, Grosvenor Street, UK
    Biomacromolecules 4:387-94. 2003
    ....
  43. ncbi request reprint Conformation transition in silk protein films monitored by time-resolved Fourier transform infrared spectroscopy: effect of potassium ions on Nephila spidroin films
    Xin Chen
    Department of Macromolecular Science, The Key Laboratory of Molecular Engineering of Polymers of Education Ministry, Fudan University, Shanghai 200433, People s Republic of China
    Biochemistry 41:14944-50. 2002
    ..We discuss the possible significance of these findings to an understanding of the way that spiders spin silk...
  44. ncbi request reprint Further investigation on potassium-induced conformation transition of Nephila spidroin film with two-dimensional infrared correlation spectroscopy
    Xianneng Peng
    Department of Macromolecular Science, The Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai, 200433, People s Republic of China
    Biomacromolecules 6:302-8. 2005
    ..We present a single coherent and detailed hypothesis for the assembly and secondary structural transition of silk proteins in vivo and in vitro based on our findings and on evidence from other laboratories...
  45. ncbi request reprint Surprising strength of silkworm silk
    Zhengzhong Shao
    Department of Macromolecular Science and Key Laboratory of Polymer Engineering of Education Ministry, Fudan University, Shanghai 200433, China
    Nature 418:741. 2002
    ..We suggest that silkworms might be able to produce threads that compare well with spider silk by changing their spinning habits, rather than by having their silk genes altered...
  46. ncbi request reprint Amyloidogenic nature of spider silk
    John M Kenney
    Institute for Storage Ring Facilities, University of Aarhus, Denmark
    Eur J Biochem 269:4159-63. 2002
    ..We also propose that spider silk could be a valuable model system for testing hypotheses concerning beta-sheet formation in other fibrilogenic systems, including amyloids...
  47. ncbi request reprint Spider silk proteins--mechanical property and gene sequence
    Anna Rising
    Department of Pathology, Swedish University of Agricultural Sciences BioMedical Centre, Uppsala, Sweden
    Zoolog Sci 22:273-81. 2005
    ..This review aims to link recent molecular data, often translated into amino acid sequences and predicted three dimensional structural motifs, to known mechanical properties...
  48. ncbi request reprint Influence of CO2 on the micro-structural properties of spider dragline silk: X-ray microdiffraction results
    Christian Riekel
    European Synchrotron Radiation Facility, BP 220, 38043 Grenoble Cedex, France
    Naturwissenschaften 91:30-3. 2004
    ..Long CO(2) exposure reduces the axial alignment of nanofibrils, presumably due to a partial destruction of the amorphous network...
  49. ncbi request reprint Relationships between supercontraction and mechanical properties of spider silk
    Yi Liu
    Department of Macromolecular Science and The Key Laboratory of Molecular Engineering of Polymers of Ministry of Education, Fudan University, Shanghai 200433, PR China
    Nat Mater 4:901-5. 2005
    ..This interaction reveals design principles linking the exceptional properties of silk to its molecular orientation...
  50. ncbi request reprint Characterization of the protein components of Nephila clavipes dragline silk
    Alexander Sponner
    Department of Biochemistry, Institute for Molecular Biotechnology, Beutenbergstrasse 11, 07745 Jena, Germany
    Biochemistry 44:4727-36. 2005
    ..Depending on the preparation, some silk material readily underwent degradation, and polypeptides down to 20 kDa in size and less were detectable...
  51. ncbi request reprint Beta-silks: enhancing and controlling aggregation
    Cedric Dicko
    Zoology Department, Oxford University, OX1 3PS, United Kingdom
    Adv Protein Chem 73:17-53. 2006
    ..Here we review fiber formation and its prerequisites, and discuss the mechanism by which the animal facilitates and modulates silk assembly to achieve controlled protein aggregation...
  52. ncbi request reprint Conformation transition kinetics of Bombyx mori silk protein
    Xin Chen
    The Key Laboratory of Molecular Engineering of Polymers of MOE, Department of Macromolecular Science, Fudan University, Shanghai 200433, People s Republic of China
    Proteins 68:223-31. 2007
    ....
  53. ncbi request reprint African elephants run from the sound of disturbed bees
    Lucy E King
    Curr Biol 17:R832-3. 2007
  54. ncbi request reprint Spider silk protein refolding is controlled by changing pH
    Cedric Dicko
    Department of Zoology, Oxford University, OX1 3PS Oxford, United Kingdom
    Biomacromolecules 5:704-10. 2004
    ..Thus, we provide, for the first time, a quantitative map of the pH value and position correlated with molecular structural folding in the silk gland characterizing the crucial role that pH plays in spider silk formation...
  55. pmc Stable isotopes in elephant hair document migration patterns and diet changes
    Thure E Cerling
    Department of Geology and Geophysics, 135 South 1460 East, University of Utah, Salt Lake City, UT 84112, USA
    Proc Natl Acad Sci U S A 103:371-3. 2006
    ..Variation in diet, quantified by using stable isotopes, can offer insight into diet-related wildlife behavior...
  56. ncbi request reprint NMR characterization of native liquid spider dragline silk from Nephila edulis
    M Hronska
    ETH Zurich, Physical Chemistry, ETH Honggerberg, CH 8093 Zurich, Switzerland
    Biomacromolecules 5:834-9. 2004
    ..a. gland is dynamically disordered throughout the molecule in the sense that each amino acid of a given type senses an identical environment, on average. The NMR data obtained are consistent with an isotropic liquid phase...
  57. ncbi request reprint Novel assembly properties of recombinant spider dragline silk proteins
    Daniel Huemmerich
    Department of Organic Chemistry and Biochemistry, Technische Universitat Munchen, 85747 Garching, Germany
    Curr Biol 14:2070-4. 2004
    ..Our findings shed new light on the structural components of spider dragline silk, allowing further elucidation of their assembly properties, which may open the door for commercial applications...
  58. ncbi request reprint Elephants avoid costly mountaineering
    Jake Wall
    Curr Biol 16:R527-9. 2006
  59. doi request reprint Endocrine and behavioral changes in male African elephants: linking hormone changes to sexual state and reproductive tactics
    Henrik B Rasmussen
    University of Copenhagen, Department of Biology, Section of Evolutionary Biology, Universitetsparken 15, DK 2100, Copenhagen Ø, Denmark
    Horm Behav 54:539-48. 2008
    ....