Christine Vogel

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint The relationship between domain duplication and recombination
    Christine Vogel
    MRC Laboratory of Molecular Biology, Hills Rd, Cambridge CB2 2QH, UK
    J Mol Biol 346:355-65. 2005
  2. ncbi request reprint The immunoglobulin superfamily in Drosophila melanogaster and Caenorhabditis elegans and the evolution of complexity
    Christine Vogel
    MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, UK
    Development 130:6317-28. 2003
  3. ncbi request reprint Structure, function and evolution of multidomain proteins
    Christine Vogel
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Curr Opin Struct Biol 14:208-16. 2004
  4. ncbi request reprint Supra-domains: evolutionary units larger than single protein domains
    Christine Vogel
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    J Mol Biol 336:809-23. 2004
  5. pmc The SUPERFAMILY database in 2007: families and functions
    Derek Wilson
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nucleic Acids Res 35:D308-13. 2007
  6. ncbi request reprint Evolution of the protein repertoire
    Cyrus Chothia
    Structural Studies Division, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Science 300:1701-3. 2003
  7. pmc SUPERFAMILY--sophisticated comparative genomics, data mining, visualization and phylogeny
    Derek Wilson
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, Department of Computer Science, University of Bristol, The Merchant Venturers Building, Bristol BS8 1UB, UK
    Nucleic Acids Res 37:D380-6. 2009
  8. pmc The SUPERFAMILY database in 2004: additions and improvements
    Martin Madera
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nucleic Acids Res 32:D235-9. 2004
  9. pmc Protein family expansions and biological complexity
    Christine Vogel
    Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
    PLoS Comput Biol 2:e48. 2006
  10. ncbi request reprint Duplication, divergence and formation of novel protein topologies
    Christine Vogel
    Institute for Cellular and Molecular Biology, University of Texas at Austin, TX, USA
    Bioessays 28:973-8. 2006

Detail Information

Publications11

  1. ncbi request reprint The relationship between domain duplication and recombination
    Christine Vogel
    MRC Laboratory of Molecular Biology, Hills Rd, Cambridge CB2 2QH, UK
    J Mol Biol 346:355-65. 2005
    ..Some of the pair-wise domain combinations that are highly duplicated also recur frequently with other partner domains, and thus represent evolutionary units larger than single protein domains, which we term "supra-domains"...
  2. ncbi request reprint The immunoglobulin superfamily in Drosophila melanogaster and Caenorhabditis elegans and the evolution of complexity
    Christine Vogel
    MRC Laboratory of Molecular Biology, Cambridge CB2 2QH, UK
    Development 130:6317-28. 2003
    ..These results suggest that the expansion of this protein superfamily is one of the factors that have contributed to the formation of the more complex physiological features that are found in Drosophila...
  3. ncbi request reprint Structure, function and evolution of multidomain proteins
    Christine Vogel
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Curr Opin Struct Biol 14:208-16. 2004
    ..Future work will require a domain-centric functional classification scheme and efforts to determine structures of domain combinations...
  4. ncbi request reprint Supra-domains: evolutionary units larger than single protein domains
    Christine Vogel
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    J Mol Biol 336:809-23. 2004
    ..Since this is the case for only a quarter of the supra-domains, we provide a list of the most important unknown supra-domains as potential targets for structural genomics projects...
  5. pmc The SUPERFAMILY database in 2007: families and functions
    Derek Wilson
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nucleic Acids Res 35:D308-13. 2007
    ..The SUPERFAMILY database can be used for general protein evolution and superfamily-specific studies, genomic annotation, and structural genomics target suggestion and assessment...
  6. ncbi request reprint Evolution of the protein repertoire
    Cyrus Chothia
    Structural Studies Division, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Science 300:1701-3. 2003
    ..Proteins of known structure can be matched to about 50% of genome sequences, and these data provide a quantitative description and can suggest hypotheses about the origins of these processes...
  7. pmc SUPERFAMILY--sophisticated comparative genomics, data mining, visualization and phylogeny
    Derek Wilson
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, Department of Computer Science, University of Bristol, The Merchant Venturers Building, Bristol BS8 1UB, UK
    Nucleic Acids Res 37:D380-6. 2009
    ..The database, models and associated scripts are available for download from the ftp site...
  8. pmc The SUPERFAMILY database in 2004: additions and improvements
    Martin Madera
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nucleic Acids Res 32:D235-9. 2004
    ..In addition, the webserver provides the following standard services: sequence search; keyword search for genomes, superfamilies and sequence identifiers; and multiple alignment of genomic, PDB and custom sequences...
  9. pmc Protein family expansions and biological complexity
    Christine Vogel
    Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
    PLoS Comput Biol 2:e48. 2006
    ..Our work identifies important protein families and provides one explanation of the discrepancy between the total number of genes and the apparent physiological complexity of eukaryotic organisms...
  10. ncbi request reprint Duplication, divergence and formation of novel protein topologies
    Christine Vogel
    Institute for Cellular and Molecular Biology, University of Texas at Austin, TX, USA
    Bioessays 28:973-8. 2006
    ..In spite of this, circular permutations are relatively rare and we discuss possible reasons for their existence...
  11. pmc The (in)dependence of alternative splicing and gene duplication
    David Talavera
    Molecular Modeling and Bioinformatics Unit, Parc Cientific de Barcelona, Barcelona, Spain
    PLoS Comput Biol 3:e33. 2007
    ..We discuss possible explanations that relate to the order of appearance of AS and GD in a gene family, and to the selection pressure imposed by the environment...