Affiliation: University of Southampton
- Invariant natural killer T cells in asthma and chronic obstructive pulmonary diseasePandurangan Vijayanand
Division of Infection, Inflammation, and Repair, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
N Engl J Med 356:1410-22. 2007..We also studied whether an increased number of these cells is a feature of chronic obstructive pulmonary disease (COPD)...
- Chemokine receptor 4 plays a key role in T cell recruitment into the airways of asthmatic patientsPandurangan Vijayanand
Division of Infection, Southampton National Institute of Health Research Respiratory Biomedical Research Unit, University of Southampton School of Medicine, Southampton, United Kingdom
J Immunol 184:4568-74. 2010..This study also provides wider proof of concept for using tissue explants to study immunomodulatory drugs for asthma...
- EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthmaMohib Uddin
Academic Unit of Clinical and Experimental Sciences and the NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Faculty of Medicine, Sir Henry Wellcome Laboratories, Southampton University Hospital, Southampton, United Kingdom
PLoS ONE 8:e72502. 2013....
- Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibilityGregory Seumois
1 La Jolla Institute for Allergy and Immunology, La Jolla, California, USA 2 Clinical and Experimental Sciences, Southampton National Institute for Health Research Respiratory Biomedical Research Unit, University of Southampton, Faculty of Medicine, Southampton, UK 3 University of California San Francisco, San Francisco, California, USA 4
Nat Immunol 15:777-88. 2014..Our results establish the feasibility and utility of enhancer profiling in well-defined populations of specialized cell types involved in disease pathogenesis. ..