Patricia Viard

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane
    Patricia Viard
    Department of Pharmacology, University College London, London WC1E 6BT, UK
    Nat Neurosci 7:939-46. 2004
  2. ncbi request reprint Constitutive PtdIns(3,4,5)P3 synthesis promotes the development and survival of early mammalian embryos
    Guillaume Halet
    Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK
    Development 135:425-9. 2008
  3. ncbi request reprint Mechanism of action of Gq to inhibit G beta gamma modulation of CaV2.2 calcium channels: probed by the use of receptor-G alpha tandems
    Federica Bertaso
    Department of Pharmacology, University College London, London, United Kingdom
    Mol Pharmacol 63:832-43. 2003
  4. pmc The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression
    Fraser J Moss
    Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
    EMBO J 21:1514-23. 2002
  5. pmc Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels
    Jean Sebastien Rougier
    Department of Neurosciences, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom
    J Biol Chem 286:8829-38. 2011

Detail Information

Publications5

  1. ncbi request reprint PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane
    Patricia Viard
    Department of Pharmacology, University College London, London WC1E 6BT, UK
    Nat Neurosci 7:939-46. 2004
    ..The mutations S574A and S574E in Ca(v)beta(2a) prevented and mimicked, respectively, the effect of PI3K/Akt-PKB, indicating that phosphorylation of Ser574 on Ca(v)beta(2a) is necessary and sufficient to promote Ca(v) channel trafficking...
  2. ncbi request reprint Constitutive PtdIns(3,4,5)P3 synthesis promotes the development and survival of early mammalian embryos
    Guillaume Halet
    Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK
    Development 135:425-9. 2008
    ..We show that constitutive PtdIns(3,4,5)P(3) synthesis is necessary for optimal development to blastocyst and to prevent large-scale apoptosis at the time of cavitation...
  3. ncbi request reprint Mechanism of action of Gq to inhibit G beta gamma modulation of CaV2.2 calcium channels: probed by the use of receptor-G alpha tandems
    Federica Bertaso
    Department of Pharmacology, University College London, London, United Kingdom
    Mol Pharmacol 63:832-43. 2003
    ..The potential sites of phosphorylation are discussed...
  4. pmc The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression
    Fraser J Moss
    Department of Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
    EMBO J 21:1514-23. 2002
    ....
  5. pmc Neuronal precursor cell-expressed developmentally down-regulated 4-1 (NEDD4-1) controls the sorting of newly synthesized Ca(V)1.2 calcium channels
    Jean Sebastien Rougier
    Department of Neurosciences, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom
    J Biol Chem 286:8829-38. 2011
    ..Altogether, our results suggest that Nedd4-1 interferes with the chaperon role of Ca(v)β at the endoplasmic reticulum/Golgi level to prevent the delivery of Ca(v) channels at the plasma membrane...