Affiliation: University of Cambridge
- Spinal cord regenerationPoonam Verma
Cambridge University Centre for Brain Repair, Forvie Site, Robinson Way, Cambridge, CB2 2PY, UK
Adv Biochem Eng Biotechnol 94:43-66. 2005..This article reviews the impact of SCI on patients, the current reparative strategies being explored and their potential clinical applications...
- The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERKSabrina Chierzi
Cambridge University Centre for Brain Repair, Robinson Way, Cambridge CB2 2PY, UK
Eur J Neurosci 21:2051-62. 2005..Understanding the cellular mechanisms activated at the time of lesion and leading to the formation of a new growth cone is necessary for devising treatments aimed at enhancing the regenerative response of injured axons...
- Axonal protein synthesis and degradation are necessary for efficient growth cone regenerationPoonam Verma
Cambridge University Centre for Brain Repair, Cambridge CB2 2PY, United Kingdom
J Neurosci 25:331-42. 2005..Collectively, these findings suggest that local protein synthesis and degradation, controlled by various TOR-, p38 MAPK-, and caspase-dependent pathways, underlie growth cone initiation after axotomy...