Research Topics
| Juliet A Usher-SmithSummaryAffiliation: University of Cambridge Country: UK Publications
| Collaborators |
Detail Information
Publications
Factors associated with the presence of diabetic ketoacidosis at diagnosis of diabetes in children and young adults: a systematic reviewJuliet A Usher-Smith
General Practice and Primary Care Research Unit, University of Cambridge, Cambridge CB2 0SR, UK
BMJ 343:d4092. 2011..To identify the factors associated with diabetic ketoacidosis at diagnosis of type 1 diabetes in children and young adults...
Evaluation of the cost savings and clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a Primary Care settingJ A Usher-Smith
University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Cambridge, UK
Int J Clin Pract 61:15-23. 2007..No adverse events attributable to the switch were reported in either group and the net annualised savings for the year 2005-2006 were 12,715.58 pounds for the statin and 13,374.40 pounds for the antihypertensive switch, respectively...
Evaluation of the clinical outcomes of switching patients from atorvastatin to simvastatin and losartan to candesartan in a primary care setting: 2 years onJ Usher-Smith
Department of Medicine, West Suffolk Hospital NHS Trust, Suffolk, UK
Int J Clin Pract 62:480-4. 2008..This short report was designed to provide 2-year follow-up data from a previous study carried out in a primary care practice in the UK to assess the clinical and practical implications of switching to generic drugs...
Alterations in calcium homeostasis reduce membrane excitability in amphibian skeletal muscleJuliet A Usher-Smith
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, UK
Pflugers Arch 453:211-21. 2006..These novel findings suggest that sarcoplasmic reticulum Ca(2+) content profoundly influences surface membrane excitability, thereby providing a potential mechanism by which spike firing fails in well-polarised fibres during fatigue...
The influence of intracellular lactate and H+ on cell volume in amphibian skeletal muscleJuliet A Usher-Smith
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK
J Physiol 573:799-818. 2006....
Effect of repetitive stimulation on cell volume and its relationship to membrane potential in amphibian skeletal muscleJuliet A Usher-Smith
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, CB2 3EG, UK
Pflugers Arch 452:231-9. 2006....
Control of cell volume in skeletal muscleJuliet A Usher-Smith
Physiological Laboratory, Downing Street, Cambridge, CB2 3EG, UK
Biol Rev Camb Philos Soc 84:143-59. 2009..The relative contributions of these various factors to the control of cell volume in resting and exercising skeletal muscle are thus described...
Alterations in triad ultrastructure following repetitive stimulation and intracellular changes associated with exercise in amphibian skeletal muscleJuliet A Usher-Smith
Physiological Laboratory, Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK
J Muscle Res Cell Motil 28:19-28. 2007....
The effect of intracellular acidification on the relationship between cell volume and membrane potential in amphibian skeletal muscleJames A Fraser
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK
J Physiol 563:745-64. 2005....
Slow volume transients in amphibian skeletal muscle fibres studied in hypotonic solutionsJames A Fraser
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK
J Physiol 564:51-63. 2005..In contrast, the DeltaV(S-) could only be explained by an efflux of such anions and was accordingly comparable to organic anion-dependent regulatory volume decreases reported in other cell types...
Membrane potentials in Rana temporaria muscle fibres in strongly hypertonic solutionsJames A Fraser
Physiological Laboratory, University of Cambridge, Cambridge CB2 3EG, UK
J Muscle Res Cell Motil 27:591-606. 2006..However, the observed positive changes in E(m) in the most strongly hypertonic solutions eventually exceeded these predictions suggesting additional limitations on Na(+)/K(+)-ATPase activity in strongly hypertonic solutions...
Detubulation abolishes membrane potential stabilization in amphibian skeletal muscleDiana X L Chin
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, UK
J Muscle Res Cell Motil 25:379-87. 2004..When taken together with previous reports of significant Cl- conductances in the surface membrane, these findings suggest a model that contrastingly suggests a T-tubular location for cation--Cl- co-transporter activity or its regulation...
Properties of the demarcation membrane system in living rat megakaryocytesMartyn P Mahaut-Smith
Department of Physiology, University of Cambridge, Downing Street, Cambridge, UK
Biophys J 84:2646-54. 2003..Whole-cell capacitance measurements and confocal imaging of membrane-impermeant fluorescent indicators therefore represent novel approaches to monitor the DMS during megakaryocytopoiesis and thrombopoiesis...
Risk stratification for sudden cardiac deathIan N Sabir
Physiological Laboratory, University of Cambridge, Downing Street, Cambridge, UK
Prog Biophys Mol Biol 98:340-6. 2008..It is concluded that effective stratification is likely to require the use of composite parameters and that invasive procedures might only be justified in specific sub-groups of patients...
