Rebecca CJ Twells

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13
    R C Twells
    Wellcome Trust Centre for Molecular Mechanisms in Disease, University of Cambridge, Cambridge, United Kingdom
    Genomics 72:231-42. 2001
  2. ncbi request reprint Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes
    Rebecca C J Twells
    Department of Medical Genetics, JDRF WT Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Addenbrooke s Hospital, Cambridge CB2 2XY, UK
    Hum Genet 113:99-105. 2003
  3. pmc Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene
    Rebecca C J Twells
    JDRF WT Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, UK
    Genome Res 13:845-55. 2003
  4. pmc Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes
    Lisa M Maier
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, UK
    BMC Genet 6:9. 2005
  5. pmc Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping
    Rebecca Pask
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes, Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Cambridge, CB2 2XY, UK
    BMC Biotechnol 4:15. 2004

Collaborators

  • J Fred Hess
  • Heather J Cordell
  • E Levy
  • David Clayton
  • Frank Dudbridge
  • Benedicte A Lie
  • William Y S Wang
  • J A Todd
  • Rebecca Pask
  • Lisa M Maier
  • Sarah Nutland
  • Deborah J Smyth
  • Luc J Smink
  • Carolyn Moule
  • Heather Fraser
  • David A Savage
  • Neil Walker
  • Kara M Hunter
  • Laurence B Peterson
  • John Hulme
  • David P Strachan
  • Cristian Guja
  • Jason D Cooper
  • Kjersti S Rønningen
  • Constantin Ionescu-Tirgoviste
  • Giselle Chamberlain
  • Linda S Wicker
  • Felicity Payne
  • Adrian Vella
  • Christopher Lowe
  • Dag E Undlien
  • Helen E Rance
  • Bryan J Barratt
  • Anne Smith
  • Meera Sebastian
  • Neil M Walker
  • Alex C Lam

Detail Information

Publications5

  1. ncbi request reprint The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13
    R C Twells
    Wellcome Trust Centre for Molecular Mechanisms in Disease, University of Cambridge, Cambridge, United Kingdom
    Genomics 72:231-42. 2001
    ..The full-length C11orf23 cDNA is the first mammalian orthologue of the yeast SAP family to be identified. Identification of these four genes in a 400-kb region of the IDDM4 region underpins our strategy to identify the IDDM4 locus...
  2. ncbi request reprint Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes
    Rebecca C J Twells
    Department of Medical Genetics, JDRF WT Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Addenbrooke s Hospital, Cambridge CB2 2XY, UK
    Hum Genet 113:99-105. 2003
    ..The continued search for the variants of the putative IDDM4 locus will greatly benefit from the future development of a haplotype map of the genome...
  3. pmc Haplotype structure, LD blocks, and uneven recombination within the LRP5 gene
    Rebecca C J Twells
    JDRF WT Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 2XY, UK
    Genome Res 13:845-55. 2003
    ..The identification of hot spots in between these LD blocks provides additional evidence that LD blocks are separated by areas of higher recombination...
  4. pmc Construction and analysis of tag single nucleotide polymorphism maps for six human-mouse orthologous candidate genes in type 1 diabetes
    Lisa M Maier
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Hills Road, Cambridge, UK
    BMC Genet 6:9. 2005
    ..2), FRAP1 (orthologous to Frap1 in Idd9.2), 4-1BB/CD137/TNFRSF9 (orthologous to 4-1bb/Cd137/Tnrfrsf9 in Idd9.3), CD101/IGSF2 (orthologous to Cd101/Igsf2 in Idd10), B2M (orthologous to B2m in Idd13) and VAV3 (orthologous to Vav3 in Idd18)...
  5. pmc Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping
    Rebecca Pask
    Juvenile Diabetes Research Foundation Wellcome Trust Diabetes, Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust MRC Building, Cambridge, CB2 2XY, UK
    BMC Biotechnol 4:15. 2004
    ..As part of a large-scale BeadArray genotyping experiment we made a direct comparison of genotyping data generated from MDA product with that from genomic DNA (gDNA) templates...