Martin R Turner

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc An eye-tracking version of the trail-making test
    Stephen L Hicks
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
    PLoS ONE 8:e84061. 2013
  2. pmc Myelin imaging in amyotrophic and primary lateral sclerosis
    Shannon Kolind
    Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford
    Amyotroph Lateral Scler Frontotemporal Degener 14:562-73. 2013
  3. pmc Multiple kernel learning captures a systems-level functional connectivity biomarker signature in amyotrophic lateral sclerosis
    Tomer Fekete
    Department of Biomedical Engineering, Stony Brook University, New York, New York, United States of America
    PLoS ONE 8:e85190. 2013
  4. pmc Progressive hemiparesis (Mills syndrome) with aphasia in amyotrophic lateral sclerosis
    Dirk Bäumer
    From Oxford University, John Radcliffe Hospital D B, R A L M, K T, M H, M R T Milton Keynes Hospital NHS Trust R B, Buckinghamshire and Oxford University, Warneford Hospital R A L M, UK
    Neurology 82:457-8. 2014
  5. pmc Mimics and chameleons in motor neurone disease
    Martin R Turner
    University of Oxford Nuffield Department of Clinical Neurosciences, Oxford, UK
    Pract Neurol 13:153-64. 2013
  6. ncbi request reprint Mechanisms, models and biomarkers in amyotrophic lateral sclerosis
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, University of Oxford, UK
    Amyotroph Lateral Scler Frontotemporal Degener 14:19-32. 2013
  7. doi request reprint Neuroimaging in amyotrophic lateral sclerosis
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, Oxford University, UK
    Biomark Med 6:319-37. 2012
  8. doi request reprint Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: indirect evidence from record linkage study
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
    J Neurol Neurosurg Psychiatry 83:395-8. 2012
  9. pmc Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study
    Martin R Turner
    From the Oxford University Nuffield Department of Clinical Neurosciences M R T, K T, John Radcliffe Hospital Oxford University Unit of Health Care Epidemiology R G, M J G, Department of Public Health and Oxford University Department of Physiology, Anatomy and Genetics S R, Oxford, UK
    Neurology 81:1222-5. 2013
  10. doi request reprint Biomarkers in amyotrophic lateral sclerosis
    Martin R Turner
    Department of Clinical Neurology, University of Oxford, Oxford, UK
    Lancet Neurol 8:94-109. 2009

Collaborators

Detail Information

Publications31

  1. pmc An eye-tracking version of the trail-making test
    Stephen L Hicks
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom
    PLoS ONE 8:e84061. 2013
    ..There was good correlation for speed between both versions of Part B (R(2)=0.73), suggesting that this is a viable method to objectively assess cognitive impairment in disorders where patients are unable to speak or write. ..
  2. pmc Myelin imaging in amyotrophic and primary lateral sclerosis
    Shannon Kolind
    Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford
    Amyotroph Lateral Scler Frontotemporal Degener 14:562-73. 2013
    ..PLS may be a more active cerebral pathological process than its rate of clinical deterioration suggests...
  3. pmc Multiple kernel learning captures a systems-level functional connectivity biomarker signature in amyotrophic lateral sclerosis
    Tomer Fekete
    Department of Biomedical Engineering, Stony Brook University, New York, New York, United States of America
    PLoS ONE 8:e85190. 2013
    ..As the understanding of neurodegenerative disorders moves towards studying pre-symptomatic changes, there is potential for this type of approach to generate biomarkers for the testing of neuroprotective strategies. ..
  4. pmc Progressive hemiparesis (Mills syndrome) with aphasia in amyotrophic lateral sclerosis
    Dirk Bäumer
    From Oxford University, John Radcliffe Hospital D B, R A L M, K T, M H, M R T Milton Keynes Hospital NHS Trust R B, Buckinghamshire and Oxford University, Warneford Hospital R A L M, UK
    Neurology 82:457-8. 2014
    ..Frank FTD is seen in up to 15% of patients with ALS, in whom it typically occurs before or soon after the development of motor symptoms, and is associated with a more rapid disease progression.(3.) ..
  5. pmc Mimics and chameleons in motor neurone disease
    Martin R Turner
    University of Oxford Nuffield Department of Clinical Neurosciences, Oxford, UK
    Pract Neurol 13:153-64. 2013
    ....
  6. ncbi request reprint Mechanisms, models and biomarkers in amyotrophic lateral sclerosis
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, University of Oxford, UK
    Amyotroph Lateral Scler Frontotemporal Degener 14:19-32. 2013
    ....
  7. doi request reprint Neuroimaging in amyotrophic lateral sclerosis
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, Oxford University, UK
    Biomark Med 6:319-37. 2012
    ..This comprehensive review considers the full range of neuroimaging techniques applied to amyotrophic lateral sclerosis over the last 25 years, the biomarkers they have revealed and future developments...
  8. doi request reprint Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: indirect evidence from record linkage study
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
    J Neurol Neurosurg Psychiatry 83:395-8. 2012
    ..Hospital admission for coronary heart disease (CHD) might serve as an objective marker of reduced cardiovascular fitness...
  9. pmc Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study
    Martin R Turner
    From the Oxford University Nuffield Department of Clinical Neurosciences M R T, K T, John Radcliffe Hospital Oxford University Unit of Health Care Epidemiology R G, M J G, Department of Public Health and Oxford University Department of Physiology, Anatomy and Genetics S R, Oxford, UK
    Neurology 81:1222-5. 2013
    ..To study whether the risk of amyotrophic lateral sclerosis (ALS) is increased in people with prior autoimmune disease...
  10. doi request reprint Biomarkers in amyotrophic lateral sclerosis
    Martin R Turner
    Department of Clinical Neurology, University of Oxford, Oxford, UK
    Lancet Neurol 8:94-109. 2009
    ..Such biomarkers might also resolve complexities of phenotypic heterogeneity in clinical trials. In this Review, we discuss the development of biomarkers in ALS and consider potential future directions for research...
  11. ncbi request reprint Young-onset amyotrophic lateral sclerosis: historical and other observations
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Brain 135:2883-91. 2012
    ..The timing of initiating pathological processes in relation to the emergence of symptoms is discussed, including the potential role of very early development and the interaction of epigenetic and environmental factors...
  12. pmc Pattern of spread and prognosis in lower limb-onset ALS
    Martin R Turner
    Oxford University Department of Clinical Neurology, Oxford, UK
    Amyotroph Lateral Scler 11:369-73. 2010
    ..The time interval to this initial spread is a powerful factor in predicting overall survival, and could be used to facilitate decision-making and effective care planning...
  13. pmc T2-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS
    Matthew C Evans
    1 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK 2 CR UK MRC Gray Institute for Radiation Oncology and Biology, Department of Oncology, University of Oxford, Oxford, UK
    J Cereb Blood Flow Metab 34:785-93. 2014
    ....
  14. doi request reprint Oculomotor dysfunction in amyotrophic lateral sclerosis: a comprehensive review
    Rakesh Sharma
    Oxford University Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom
    Arch Neurol 68:857-61. 2011
    ..The study of oculomotor dysfunction holds significant promise as an additional source of much needed prognostic, monitoring, and mechanistic biomarkers for ALS...
  15. pmc Advances in motor neurone disease
    Dirk Bäumer
    Nuffield Department of Clinical Neurosciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, UK
    J R Soc Med 107:14-21. 2014
    ..A major gap remains in understanding how such fundamental processes appear to function without obvious deficit in the decades prior to symptom emergence, and the study of pre-symptomatic gene carriers is an important new initiative. ..
  16. ncbi request reprint Epilepsy and the subsequent risk of cerebral tumour: record linkage retrospective cohort study
    Tasneem Khan
    University of Oxford Medical School, John Radcliffe Hospital, Oxford, UK
    J Neurol Neurosurg Psychiatry 82:1041-5. 2011
    ..Studies suggest that seizures may precede the detection of cerebral tumour by several years. Aim To quantify the risk of cerebral tumour after new onset seizures, with particular interest in long term risk...
  17. doi request reprint Head and other physical trauma requiring hospitalisation is not a significant risk factor in the development of ALS
    Martin R Turner
    Oxford University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    J Neurol Sci 288:45-8. 2010
    ..The high risk of head injury observed in the immediate post-diagnosis period may be amenable to primary prevention...
  18. doi request reprint Trends in death certification for multiple sclerosis, motor neuron disease, Parkinson's disease and epilepsy in English populations 1979-2006
    Michael J Goldacre
    Unit of Health Care Epidemiology, Department of Public Health, University of Oxford, Old Road Campus, Oxford OX3 7LF, UK
    J Neurol 257:706-15. 2010
    ..A substantial percentage of neurological deaths are missed. Time trends may be misleading. All certified causes for each disease, as well as the underlying cause, should be analysed...
  19. pmc Whole-brain magnetic resonance spectroscopic imaging measures are related to disability in ALS
    Charlotte J Stagg
    Centre for Functional Magnetic Resonance of the Brain, University of Oxford, UK
    Neurology 80:610-5. 2013
    ....
  20. doi request reprint Does interneuronal dysfunction contribute to neurodegeneration in amyotrophic lateral sclerosis?
    Martin R Turner
    Oxford University Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
    Amyotroph Lateral Scler 13:245-50. 2012
    ..An excitotoxic final common pathway might then result from unopposed glutamatergic activity. If correct, therapies aimed specifically at supporting interneuronal function may provide a novel therapeutic strategy...
  21. doi request reprint Magnetic resonance imaging of pathological processes in rodent models of amyotrophic lateral sclerosis
    Matthew C Evans
    Oxford University Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK
    Amyotroph Lateral Scler 13:288-301. 2012
    ..These are potentially important steps towards the ultimate goal of human therapeutic translation...
  22. pmc Lockhart Clarke's contribution to the description of amyotrophic lateral sclerosis
    Martin R Turner
    Department of Clinical Neurology, West Wing Level 3, John Radcliffe Hospital, Oxford University, Oxford OX3 9DU, UK
    Brain 133:3470-9. 2010
    ..These 'past masters' still have much to teach us...
  23. ncbi request reprint The diagnostic pathway and prognosis in bulbar-onset amyotrophic lateral sclerosis
    Martin R Turner
    Oxford University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
    J Neurol Sci 294:81-5. 2010
    ..Diagnostic delay is a common occurrence in ALS, and many BO patients report having attended other specialist clinics prior to diagnosis...
  24. ncbi request reprint Controversies and priorities in amyotrophic lateral sclerosis
    Martin R Turner
    Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Lancet Neurol 12:310-22. 2013
    ....
  25. doi request reprint Integration of structural and functional magnetic resonance imaging in amyotrophic lateral sclerosis
    Gwenaelle Douaud
    Oxford Centre for Functional Magnetic Resonance of the Brain FMRIB, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Brain 134:3470-9. 2011
    ....
  26. doi request reprint The borderland of neuromyelitis optica
    Lucy A E Matthews
    Specialist Registrar in Neurology, Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
    Pract Neurol 9:335-40. 2009
    ..We describe two cases of optic neuritis-only NMO, and explore the current understanding of the diagnosis and spectrum of NMO disorders...
  27. doi request reprint Cancer in patients with motor neuron disease, multiple sclerosis and Parkinson's disease: record linkage studies
    Alessandro F Fois
    Unit of Health Care Epidemiology, Department of Public Health, University of Oxford, Old Road Campus, Old Road, Oxford, UK
    J Neurol Neurosurg Psychiatry 81:215-21. 2010
    ..To determine the risk of cancer before and after the diagnosis of motor neuron disease (MND), multiple sclerosis (MS) and Parkinson's disease (PD)...
  28. pmc The internet for self-diagnosis and prognostication in ALS
    Zhongbo Chen
    Oxford University Medical School, John Radcliffe Hospital, Oxford, UK
    Amyotroph Lateral Scler 11:565-7. 2010
    ..Results in relation to 'cure' were misleading and may promulgate false hopes. There is a need to guide those with ALS (and particularly their children) to sources of reliable web-based information in addition to open discussion...
  29. doi request reprint Functional vitamin B12 deficiency
    Martin R Turner
    Department of Neurology, John Radcliffe Hospital, University of Oxford, Oxford, UK
    Pract Neurol 9:37-41. 2009
    ..Such patients may respond to repeated high-dose injections of B12...
  30. ncbi request reprint Volumetric cortical loss in sporadic and familial amyotrophic lateral sclerosis
    Martin R Turner
    Department of Neurology, John Radcliffe Hospital, Oxford, UK
    Amyotroph Lateral Scler 8:343-7. 2007
    ..This study provides further evidence for a different pattern of cortical neuronal vulnerability in homD90A versus SALS patients that may provide insight as to their slower rate of disease progression...
  31. ncbi request reprint A case of celiac disease mimicking amyotrophic lateral sclerosis
    Martin R Turner
    Department of Neurology, John Radcliffe Hospital, Oxford, UK
    Nat Clin Pract Neurol 3:581-4. 2007
    ..The thigh muscle in the affected leg showed signs of wasting. The patient had a remote family history of celiac disease...