Brian D M Tom

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Antiangiogenic agents are effective inhibitors of endometriosis
    M Louise Hull
    Department of Pathology, Reproductive Molecular Research Group, Cambridge, United Kingdom CB2 1QP
    J Clin Endocrinol Metab 88:2889-99. 2003
  2. ncbi request reprint Conservation of unique cell-surface CD antigen mosaics in HIV-1-infected individuals
    Adrian Woolfson
    University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Hills Road, Box 111, Cambridge CB2 2SP, United Kingdom
    Blood 106:1003-7. 2005
  3. ncbi request reprint Fusing microarray experiments with multivariate regression
    Walter R Gilks
    MRC Biostatistics Unit, Cambridge, UK
    Bioinformatics 21:ii137-43. 2005
  4. pmc Quality determination and the repair of poor quality spots in array experiments
    Brian D M Tom
    Medical Research Council, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK
    BMC Bioinformatics 6:234. 2005
  5. doi request reprint Intermittent observation of time-dependent explanatory variables: a multistate modelling approach
    Brian D M Tom
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK
    Stat Med 30:3520-31. 2011
  6. ncbi request reprint Event-biased referral can distort estimation of hepatitis C virus progression rate to cirrhosis, and of prognostic influences
    Bo Fu
    MRC Biostatistics Unit, Robinson Way, Institute of Public Health, University Forvie Site Robinson Way, Cambridge, Cambridgeshire, UK
    J Clin Epidemiol 60:1140-8. 2007
  7. pmc Bias in 2-part mixed models for longitudinal semicontinuous data
    Li Su
    Medical Research Council, Biostatistics Unit, Robinson Way, Cambridge CB2 0SR, UK
    Biostatistics 10:374-89. 2009
  8. pmc The versatility of multi-state models for the analysis of longitudinal data with unobservable features
    Vernon T Farewell
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 0SR, UK
    Lifetime Data Anal 20:51-75. 2014
  9. ncbi request reprint Ectopic pregnancy diagnosis and the pseudo-sac
    Ahmed A Ahmed
    Medical Research Council, Biostatistics Unit, Institute of Public Health, University Forvite Site, Cambridge, United Kingdom
    Fertil Steril 81:1225-8. 2004
  10. pmc Mixture distributions in multi-state modelling: some considerations in a study of psoriatic arthritis
    Aidan G O'Keeffe
    MRC Biostatistics Unit, Cambridge, U K
    Stat Med 32:600-19. 2013

Detail Information

Publications14

  1. ncbi request reprint Antiangiogenic agents are effective inhibitors of endometriosis
    M Louise Hull
    Department of Pathology, Reproductive Molecular Research Group, Cambridge, United Kingdom CB2 1QP
    J Clin Endocrinol Metab 88:2889-99. 2003
    ..These findings suggest that antiangiogenic agents may provide a novel therapeutic approach for the treatment of endometriosis...
  2. ncbi request reprint Conservation of unique cell-surface CD antigen mosaics in HIV-1-infected individuals
    Adrian Woolfson
    University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Hills Road, Box 111, Cambridge CB2 2SP, United Kingdom
    Blood 106:1003-7. 2005
    ..Their invariant nature indicates an irreversible component to retroviral infection and suggests the utility of CD antigen expression patterns in other disease settings...
  3. ncbi request reprint Fusing microarray experiments with multivariate regression
    Walter R Gilks
    MRC Biostatistics Unit, Cambridge, UK
    Bioinformatics 21:ii137-43. 2005
    ..Also, the variability in the quality of experimentation should be taken into account...
  4. pmc Quality determination and the repair of poor quality spots in array experiments
    Brian D M Tom
    Medical Research Council, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK
    BMC Bioinformatics 6:234. 2005
    ..Furthermore, biases may be introduced into analyses through missing information on some genes. Thus methods for appropriately replacing (imputing) missing data and/or weighting poor quality spots are required...
  5. doi request reprint Intermittent observation of time-dependent explanatory variables: a multistate modelling approach
    Brian D M Tom
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK
    Stat Med 30:3520-31. 2011
    ..We examine the bias in estimating effects associated with other variables via simulation for different modelling choices. We present an analysis of a motivating data set on physical functional disability in psoriatic arthritis patients...
  6. ncbi request reprint Event-biased referral can distort estimation of hepatitis C virus progression rate to cirrhosis, and of prognostic influences
    Bo Fu
    MRC Biostatistics Unit, Robinson Way, Institute of Public Health, University Forvie Site Robinson Way, Cambridge, Cambridgeshire, UK
    J Clin Epidemiol 60:1140-8. 2007
    ....
  7. pmc Bias in 2-part mixed models for longitudinal semicontinuous data
    Li Su
    Medical Research Council, Biostatistics Unit, Robinson Way, Cambridge CB2 0SR, UK
    Biostatistics 10:374-89. 2009
    ..Some practical issues on variance component estimation revealed through this data analysis are considered...
  8. pmc The versatility of multi-state models for the analysis of longitudinal data with unobservable features
    Vernon T Farewell
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 0SR, UK
    Lifetime Data Anal 20:51-75. 2014
    ..In addition, joint modelling of multiple processes is illustrated with application to potentially informative loss to follow-up, mis-measured or missclassified data and causal inference. ..
  9. ncbi request reprint Ectopic pregnancy diagnosis and the pseudo-sac
    Ahmed A Ahmed
    Medical Research Council, Biostatistics Unit, Institute of Public Health, University Forvite Site, Cambridge, United Kingdom
    Fertil Steril 81:1225-8. 2004
    ..To evaluate the impact of an ultrasound finding of a pseudo-sac (PS), a uterine sac without a double decidual ring or a yolk sac, on the management of cases with possible ectopic pregnancy...
  10. pmc Mixture distributions in multi-state modelling: some considerations in a study of psoriatic arthritis
    Aidan G O'Keeffe
    MRC Biostatistics Unit, Cambridge, U K
    Stat Med 32:600-19. 2013
    ..Furthermore, we fit a mover-stayer model that allows a dependence of the probability of a patient being a stayer on a patient-level explanatory variable...
  11. ncbi request reprint Variation in thresholds for reporting mobility disability between national population subgroups and studies
    David Melzer
    Department of Public Health and Primary Care, University of Cambridge, Cambridge CB2 2SR, UK
    J Gerontol A Biol Sci Med Sci 59:1295-303. 2004
    ..We also aimed to compare reported and tested performance across two national population studies...
  12. ncbi request reprint Is there disparity between risk and incidence of cardiovascular disease after liver transplant?
    David A J Neal
    Department of Medicine, University of Cambridge, School of Clinical Medicine, Addenbrooke s Hospital, Cambridge, UK
    Transplantation 77:93-9. 2004
    ....
  13. ncbi request reprint Endothelial cells preparing to die by apoptosis initiate a program of transcriptome and glycome regulation
    Nicola A Johnson
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    FASEB J 18:188-90. 2004
    ..We propose that the transcriptome and glycome regulation presented here synergize with previously described protein-based changes to guide the apoptotic program...
  14. ncbi request reprint Performance tests and disability: developing an objective index of mobility-related limitation in older populations
    Tzuo Yun Lan
    Department of Public Health and Primary Care, University of Cambridge, United Kingdom
    J Gerontol A Biol Sci Med Sci 57:M294-301. 2002
    ..This study aimed to identify an index of mobility-related limitations composed of physiological measures that are most closely associated with reported mobility disability in elders...