Research Topics
| Philippe N ToblerSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
The role of moral utility in decision making: an interdisciplinary frameworkPhilippe N Tobler
University of Cambridge, Cambridge, England
Cogn Affect Behav Neurosci 8:390-401. 2008..In conclusion, we suggest that moral capabilities can employ and benefit from a variety of nonmoral decision-making and learning mechanisms...
Neuronal distortions of reward probability without choicePhilippe N Tobler
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
J Neurosci 28:11703-11. 2008..Input of the distorted probability estimations to decision-making mechanisms are likely to contribute to well known inconsistencies in preferences formalized in theories of behavioral economics...- Risk-dependent reward value signal in human prefrontal cortexPhilippe N Tobler
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
Proc Natl Acad Sci U S A 106:7185-90. 2009..These results demonstrate an aggregate risk and value signal in the prefrontal cortex that would be compatible with basic assumptions underlying the mean-variance approach to utility... 
Awfully afraid? Dissociating decision- from motor- and sensory-related brain activation during perceptual choicesPhilippe N Tobler
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
J Neurosci 27:6081-2. 2007- Learning-related human brain activations reflecting individual financesPhilippe N Tobler
Department of Physiology, Development, and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
Neuron 54:167-75. 2007..The inverse relationship of behavioral and neuronal learning speed with personal finances is compatible with the general concept of decreasing marginal utility with increasing wealth... - Reward value coding distinct from risk attitude-related uncertainty coding in human reward systemsPhilippe N Tobler
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
J Neurophysiol 97:1621-32. 2007..These data demonstrate the distinct coding in key reward structures of the two basic and crucial decision parameters, expected value, and uncertainty... - Human neural learning depends on reward prediction errors in the blocking paradigmPhilippe N Tobler
Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK
J Neurophysiol 95:301-10. 2006..These data suggest that learning in primary reward structures in the human brain correlates with prediction errors in a manner that complies with principles of formal learning theory... - Coding of predicted reward omission by dopamine neurons in a conditioned inhibition paradigmPhilippe N Tobler
Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, United Kingdom
J Neurosci 23:10402-10. 2003..The neuronal responses appear to reflect reward prediction errors, thus suggesting an extension of the correspondence between learning theory and activity of single dopamine neurons to the prediction of nonreward... - Neural correlates of value, risk, and risk aversion contributing to decision making under riskGeorge I Christopoulos
Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK
J Neurosci 29:12574-83. 2009..More generally, these biological data contribute to the validity of the theoretical decision parameters for actual decisions under risk... - Neuronal signals for reward risk in frontal cortexWolfram Schultz
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
Ann N Y Acad Sci 1239:109-17. 2011..These neurophysiological mechanisms of reward risk on economic decisions inform and validate theories of economic decision making under uncertainty... - Adaptive coding of reward value by dopamine neuronsPhilippe N Tobler
Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK, and Institute of Physiology, University of Fribourg, CH-1700 Fribourg, Switzerland
Science 307:1642-5. 2005..Responses shifted relative to the expected reward value, and the gain adjusted to the variance of reward value. In this way, dopamine neurons maintained their reward sensitivity over a large range of reward values... - Short-term temporal discounting of reward value in human ventral striatumLucy Gregorios-Pippas
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
J Neurophysiol 101:1507-23. 2009..Comparisons with electrophysiological animal data suggest that ventral striatal reward discounting may involve dopaminergic and orbitofrontal inputs... - Explicit neural signals reflecting reward uncertaintyWolfram Schultz
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
Philos Trans R Soc Lond B Biol Sci 363:3801-11. 2008..The brain can use the uncertainty signals to assess the uncertainty of rewards, influence learning, modulate the value of uncertain rewards and make appropriate behavioural choices between only partly known options... - Neural mechanisms of observational learningChristopher J Burke
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
Proc Natl Acad Sci U S A 107:14431-6. 2010..In a functional MRI experiment, we found that brain activity in the dorsolateral prefrontal cortex and the ventromedial prefrontal cortex respectively corresponded to these two distinct observational learning signals... - BOLD responses in reward regions to hypothetical and imaginary monetary rewardsKrishna P Miyapuram
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Site, Cambridge, CB23DY, UK
Neuroimage 59:1692-9. 2012..Graded activation in midbrain was observed to stimuli predicting increasing hypothetical rewards. The results demonstrate the efficacy of using hypothetical monetary rewards in fMRI studies... - Discrete coding of reward probability and uncertainty by dopamine neuronsChristopher D Fiorillo
Institute of Physiology, University of Fribourg, CH 1700 Fribourg, Switzerland
Science 299:1898-902. 2003..The coding of uncertainty suggests a possible role for dopamine signals in attention-based learning and risk-taking behavior... - Striatal BOLD Response Reflects the Impact of Herd Information on Financial DecisionsChristopher J Burke
Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK
Front Hum Neurosci 4:48. 2010..These findings lend weight to the notion that the ventral striatum is involved in the processing of complex social aspects of decision making and identify a possible neural basis for herd behavior... - Personality-dependent dissociation of absolute and relative loss processing in orbitofrontal cortexJuri Fujiwara
Division of Systems Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai, Japan
Eur J Neurosci 27:1547-52. 2008..These results suggest that personality affects loss-related processing through the lateral OFC, and propose a dissociation of personality dimension and loss type on the neuronal level... - Role of human frontal and supplementary eye fields in double step saccadesPhilippe N Tobler
Institute of Psychology, Department of Neurology, Inselspital, University of Bern, Switzerland
Neuroreport 13:253-5. 2002..Thus, FEF might participate in target memorization whereas SEF is confirmed to code order information for sequential saccades even in this paradigm of only two consecutive movements...