Philippe N Tobler

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. doi request reprint The role of moral utility in decision making: an interdisciplinary framework
    Philippe N Tobler
    University of Cambridge, Cambridge, England
    Cogn Affect Behav Neurosci 8:390-401. 2008
  2. pmc Neuronal distortions of reward probability without choice
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    J Neurosci 28:11703-11. 2008
  3. pmc Risk-dependent reward value signal in human prefrontal cortex
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
    Proc Natl Acad Sci U S A 106:7185-90. 2009
  4. ncbi request reprint Awfully afraid? Dissociating decision- from motor- and sensory-related brain activation during perceptual choices
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    J Neurosci 27:6081-2. 2007
  5. ncbi request reprint Learning-related human brain activations reflecting individual finances
    Philippe N Tobler
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
    Neuron 54:167-75. 2007
  6. pmc Reward value coding distinct from risk attitude-related uncertainty coding in human reward systems
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    J Neurophysiol 97:1621-32. 2007
  7. pmc Human neural learning depends on reward prediction errors in the blocking paradigm
    Philippe N Tobler
    Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK
    J Neurophysiol 95:301-10. 2006
  8. ncbi request reprint Coding of predicted reward omission by dopamine neurons in a conditioned inhibition paradigm
    Philippe N Tobler
    Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    J Neurosci 23:10402-10. 2003
  9. pmc Neural correlates of value, risk, and risk aversion contributing to decision making under risk
    George I Christopoulos
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK
    J Neurosci 29:12574-83. 2009
  10. doi request reprint Neuronal signals for reward risk in frontal cortex
    Wolfram Schultz
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    Ann N Y Acad Sci 1239:109-17. 2011

Detail Information

Publications19

  1. doi request reprint The role of moral utility in decision making: an interdisciplinary framework
    Philippe N Tobler
    University of Cambridge, Cambridge, England
    Cogn Affect Behav Neurosci 8:390-401. 2008
    ..In conclusion, we suggest that moral capabilities can employ and benefit from a variety of nonmoral decision-making and learning mechanisms...
  2. pmc Neuronal distortions of reward probability without choice
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    J Neurosci 28:11703-11. 2008
    ..Input of the distorted probability estimations to decision-making mechanisms are likely to contribute to well known inconsistencies in preferences formalized in theories of behavioral economics...
  3. pmc Risk-dependent reward value signal in human prefrontal cortex
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
    Proc Natl Acad Sci U S A 106:7185-90. 2009
    ..These results demonstrate an aggregate risk and value signal in the prefrontal cortex that would be compatible with basic assumptions underlying the mean-variance approach to utility...
  4. ncbi request reprint Awfully afraid? Dissociating decision- from motor- and sensory-related brain activation during perceptual choices
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    J Neurosci 27:6081-2. 2007
  5. ncbi request reprint Learning-related human brain activations reflecting individual finances
    Philippe N Tobler
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, United Kingdom
    Neuron 54:167-75. 2007
    ..The inverse relationship of behavioral and neuronal learning speed with personal finances is compatible with the general concept of decreasing marginal utility with increasing wealth...
  6. pmc Reward value coding distinct from risk attitude-related uncertainty coding in human reward systems
    Philippe N Tobler
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    J Neurophysiol 97:1621-32. 2007
    ..These data demonstrate the distinct coding in key reward structures of the two basic and crucial decision parameters, expected value, and uncertainty...
  7. pmc Human neural learning depends on reward prediction errors in the blocking paradigm
    Philippe N Tobler
    Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, UK
    J Neurophysiol 95:301-10. 2006
    ..These data suggest that learning in primary reward structures in the human brain correlates with prediction errors in a manner that complies with principles of formal learning theory...
  8. ncbi request reprint Coding of predicted reward omission by dopamine neurons in a conditioned inhibition paradigm
    Philippe N Tobler
    Department of Anatomy, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    J Neurosci 23:10402-10. 2003
    ..The neuronal responses appear to reflect reward prediction errors, thus suggesting an extension of the correspondence between learning theory and activity of single dopamine neurons to the prediction of nonreward...
  9. pmc Neural correlates of value, risk, and risk aversion contributing to decision making under risk
    George I Christopoulos
    Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3DY, UK
    J Neurosci 29:12574-83. 2009
    ..More generally, these biological data contribute to the validity of the theoretical decision parameters for actual decisions under risk...
  10. doi request reprint Neuronal signals for reward risk in frontal cortex
    Wolfram Schultz
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    Ann N Y Acad Sci 1239:109-17. 2011
    ..These neurophysiological mechanisms of reward risk on economic decisions inform and validate theories of economic decision making under uncertainty...
  11. ncbi request reprint Adaptive coding of reward value by dopamine neurons
    Philippe N Tobler
    Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK, and Institute of Physiology, University of Fribourg, CH 1700 Fribourg, Switzerland
    Science 307:1642-5. 2005
    ..Responses shifted relative to the expected reward value, and the gain adjusted to the variance of reward value. In this way, dopamine neurons maintained their reward sensitivity over a large range of reward values...
  12. pmc Short-term temporal discounting of reward value in human ventral striatum
    Lucy Gregorios-Pippas
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK
    J Neurophysiol 101:1507-23. 2009
    ..Comparisons with electrophysiological animal data suggest that ventral striatal reward discounting may involve dopaminergic and orbitofrontal inputs...
  13. pmc Explicit neural signals reflecting reward uncertainty
    Wolfram Schultz
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    Philos Trans R Soc Lond B Biol Sci 363:3801-11. 2008
    ..The brain can use the uncertainty signals to assess the uncertainty of rewards, influence learning, modulate the value of uncertain rewards and make appropriate behavioural choices between only partly known options...
  14. pmc Neural mechanisms of observational learning
    Christopher J Burke
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United Kingdom
    Proc Natl Acad Sci U S A 107:14431-6. 2010
    ..In a functional MRI experiment, we found that brain activity in the dorsolateral prefrontal cortex and the ventromedial prefrontal cortex respectively corresponded to these two distinct observational learning signals...
  15. doi request reprint BOLD responses in reward regions to hypothetical and imaginary monetary rewards
    Krishna P Miyapuram
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Site, Cambridge, CB23DY, UK
    Neuroimage 59:1692-9. 2012
    ..Graded activation in midbrain was observed to stimuli predicting increasing hypothetical rewards. The results demonstrate the efficacy of using hypothetical monetary rewards in fMRI studies...
  16. ncbi request reprint Discrete coding of reward probability and uncertainty by dopamine neurons
    Christopher D Fiorillo
    Institute of Physiology, University of Fribourg, CH 1700 Fribourg, Switzerland
    Science 299:1898-902. 2003
    ..The coding of uncertainty suggests a possible role for dopamine signals in attention-based learning and risk-taking behavior...
  17. pmc Striatal BOLD Response Reflects the Impact of Herd Information on Financial Decisions
    Christopher J Burke
    Department of Physiology, Development and Neuroscience, University of Cambridge Cambridge, UK
    Front Hum Neurosci 4:48. 2010
    ..These findings lend weight to the notion that the ventral striatum is involved in the processing of complex social aspects of decision making and identify a possible neural basis for herd behavior...
  18. doi request reprint Personality-dependent dissociation of absolute and relative loss processing in orbitofrontal cortex
    Juri Fujiwara
    Division of Systems Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai, Japan
    Eur J Neurosci 27:1547-52. 2008
    ..These results suggest that personality affects loss-related processing through the lateral OFC, and propose a dissociation of personality dimension and loss type on the neuronal level...
  19. ncbi request reprint Role of human frontal and supplementary eye fields in double step saccades
    Philippe N Tobler
    Institute of Psychology, Department of Neurology, Inselspital, University of Bern, Switzerland
    Neuroreport 13:253-5. 2002
    ..Thus, FEF might participate in target memorization whereas SEF is confirmed to code order information for sequential saccades even in this paradigm of only two consecutive movements...