D J Tobin

Summary

Affiliation: University of Bradford
Country: UK

Publications

  1. ncbi A possible role for Langerhans cells in the removal of melanin from early catagen hair follicles
    D J Tobin
    Department of Biomedical Sciences, University of Bradford, West Yorkshire, U K
    Br J Dermatol 138:795-8. 1998
  2. ncbi Plasticity and cytokinetic dynamics of the hair follicle mesenchyme during the hair growth cycle: implications for growth control and hair follicle transformations
    Desmond J Tobin
    Department of Biomedical Sciences, School of Life Sciences, University of Bradford, Bradford, West Yorkshire, UK
    J Investig Dermatol Symp Proc 8:80-6. 2003
  3. ncbi Hair pigmentation: a research update
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire, UK
    J Investig Dermatol Symp Proc 10:275-9. 2005
  4. ncbi Hair melanocytes as neuro-endocrine sensors--pigments for our imagination
    D J Tobin
    Cutaneous Biology Research Group, Medical Biosciences, School of Life Sciences, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK
    Mol Cell Endocrinol 243:1-11. 2005
  5. ncbi Beta-endorphin: the forgotten hair follicle melanotropin
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire, UK
    J Investig Dermatol Symp Proc 10:212-6. 2005
  6. ncbi Biochemistry of human skin--our brain on the outside
    Desmond J Tobin
    Medical Biosciences, School of Life Sciences, University of Bradford, West Yorkshire, England, UK
    Chem Soc Rev 35:52-67. 2006
  7. ncbi Yesterday's hair--human hair in archaeology
    A S Wilson
    Department of Archaeological Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK
    Biologist (London) 48:213-7. 2001
  8. ncbi Differential expression of nitric oxide synthases in human scalp epidermal and hair follicle pigmentary units: implications for regulation of melanogenesis
    H M Sowden
    Department of Biomedical Sciences, School of Life Sciences, University of Bradford, Bradford BD7 1DP, UK
    Br J Dermatol 153:301-9. 2005
  9. ncbi Graying: gerontobiology of the hair follicle pigmentary unit
    D J Tobin
    Department of Biomedical Sciences, University of Bradford, West Yorkshire BD7 1DP, Bradford, UK
    Exp Gerontol 36:29-54. 2001
  10. ncbi Human hair pigmentation--biological aspects
    D J Tobin
    Centre for Skin Sciences, School of Life Sciences, University of Bradford, Richmond Road, Bradford, West Yorkshire, UK
    Int J Cosmet Sci 30:233-57. 2008

Collaborators

Detail Information

Publications62

  1. ncbi A possible role for Langerhans cells in the removal of melanin from early catagen hair follicles
    D J Tobin
    Department of Biomedical Sciences, University of Bradford, West Yorkshire, U K
    Br J Dermatol 138:795-8. 1998
    ....
  2. ncbi Plasticity and cytokinetic dynamics of the hair follicle mesenchyme during the hair growth cycle: implications for growth control and hair follicle transformations
    Desmond J Tobin
    Department of Biomedical Sciences, School of Life Sciences, University of Bradford, Bradford, West Yorkshire, UK
    J Investig Dermatol Symp Proc 8:80-6. 2003
    ....
  3. ncbi Hair pigmentation: a research update
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire, UK
    J Investig Dermatol Symp Proc 10:275-9. 2005
    ....
  4. ncbi Hair melanocytes as neuro-endocrine sensors--pigments for our imagination
    D J Tobin
    Cutaneous Biology Research Group, Medical Biosciences, School of Life Sciences, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK
    Mol Cell Endocrinol 243:1-11. 2005
    ..This review explores this concept and describes how the components of the CRH/POMC systems may help regulate the human hair follicle pigmentary unit...
  5. ncbi Beta-endorphin: the forgotten hair follicle melanotropin
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire, UK
    J Investig Dermatol Symp Proc 10:212-6. 2005
    ..g., immune cells, fibroblasts, and endothelial cells), and can also be released from cutaneous sensory nerve endings (cf. Slominski et al, 2004)...
  6. ncbi Biochemistry of human skin--our brain on the outside
    Desmond J Tobin
    Medical Biosciences, School of Life Sciences, University of Bradford, West Yorkshire, England, UK
    Chem Soc Rev 35:52-67. 2006
    ..This tutorial review introduces the reader to some of the biochemistry that underpins the skin's enormous multi-functionality...
  7. ncbi Yesterday's hair--human hair in archaeology
    A S Wilson
    Department of Archaeological Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK
    Biologist (London) 48:213-7. 2001
    ..But hair is also biodegradable and the effects of time and burial conditions can result in conflicting evidence of past lives...
  8. ncbi Differential expression of nitric oxide synthases in human scalp epidermal and hair follicle pigmentary units: implications for regulation of melanogenesis
    H M Sowden
    Department of Biomedical Sciences, School of Life Sciences, University of Bradford, Bradford BD7 1DP, UK
    Br J Dermatol 153:301-9. 2005
    ..Another example of possible NO involvement in HF biology is the postsynthetic modification of trichohyalin in differentiating keratinocytes of the IRS. These results suggest that NO may influence several aspects of HF biology...
  9. ncbi Graying: gerontobiology of the hair follicle pigmentary unit
    D J Tobin
    Department of Biomedical Sciences, University of Bradford, West Yorkshire BD7 1DP, Bradford, UK
    Exp Gerontol 36:29-54. 2001
    ..g. osteoporosis. Here, we review the current state of knowledge of the development, regulation and control of the human hair follicle pigmentary unit during life...
  10. ncbi Human hair pigmentation--biological aspects
    D J Tobin
    Centre for Skin Sciences, School of Life Sciences, University of Bradford, Richmond Road, Bradford, West Yorkshire, UK
    Int J Cosmet Sci 30:233-57. 2008
    ..In the longer term, it may be feasible to develop hair colour modifiers of a biological nature to accompany those based on chemicals...
  11. ncbi The fate of hair follicle melanocytes during the hair growth cycle
    D J Tobin
    Department of Biomedical Sciences, University of Bradford, UK
    J Investig Dermatol Symp Proc 4:323-32. 1999
    ....
  12. ncbi Transforming growth factor-beta receptor II is preferentially expressed in the companion layer of the human anagen hair follicle
    H M Sowden
    Medical Biosciences Research, School of Life Sciences, University of Bradford, Bradford BD7 1DP, U K
    Br J Dermatol 157:161-4. 2007
    ..While TGF-beta receptor I (TGF-beta RI) and receptor II (TGF-beta RII) expression helps define early human hair follicle morphogenesis, expression in the adult human hair follicle remains to be established...
  13. ncbi alpha-MSH can control the essential cofactor 6-tetrahydrobiopterin in melanogenesis
    K U Schallreuter
    Clinical and Experimental Dermatology Department of Biomedical Sciences, University of Bradford, United Kingdom
    Ann N Y Acad Sci 885:329-41. 1999
    ..In conclusion, alpha-MSH can control (1) intracellular L-tyrosine formation from L-phenylalanine in both melanocytes and keratinocytes, and (2) tyrosinase activity, directly, in melanocytes...
  14. ncbi Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells
    J Ancans
    Department of Biomedical Sciences, University of Bradford, Bradford, BD7 1DP, United Kingdom
    Exp Cell Res 268:26-35. 2001
    ..We would further propose that the wide variations in both constitutive and facultative skin pigmentation seen in the human population could be associated with the high degree of P-locus polymorphism...
  15. ncbi Intermediate hair follicles: a new more clinically relevant model for hair growth investigations
    B H Miranda
    Plastic Surgery and Burns Research Unit and Centre for Skin Sciences, School of Life Sciences, University of Bradford, Bradford BD7 1DP, UK
    Br J Dermatol 163:287-95. 2010
    ..Although intermediate and vellus hair follicles are the main clinical targets for pharmacological therapy, terminal hair follicles are more frequently studied as smaller hair follicles are more difficult to obtain...
  16. ncbi Selective biodegradation in hair shafts derived from archaeological, forensic and experimental contexts
    A S Wilson
    Medical Biosciences, and Archaelogical Sciences, School of Life Sciences, University of Bradford, Bradford, West Yorkshire, UK
    Br J Dermatol 157:450-7. 2007
    ....
  17. ncbi In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase
    K U Schallreuter
    Clinical and Experimental Dermatology, Department of Biomedical Sciences, University of Bradford, UK
    J Investig Dermatol Symp Proc 4:91-6. 1999
    ..In conclusion, there are several lines of evidence that the entire epidermis of patients with vitiligo is involved in the disease process and that correction of the epidermal redox status is mandatory for repigmentation...
  18. ncbi A natural canine homologue of alopecia areata in humans
    D J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, UK
    Br J Dermatol 149:938-50. 2003
    ....
  19. ncbi Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis
    Karine Rousseau
    Faculty of Life Sciences, Stopford Bldg, University of Manchester, Manchester M13 9PT, UK
    FASEB J 21:1844-56. 2007
    ..POMC also increased melanogenesis and dendricity in human pigment cells. This release of POMC from skin cells and its functional activity at the MC-1R highlight the importance of POMC processing as a key regulatory event in the skin...
  20. ncbi Changes in different melanocyte populations during hair follicle involution (catagen)
    Andreya Sharov
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts, USA
    J Invest Dermatol 125:1259-67. 2005
    ....
  21. ncbi John Martin Wood (1938-2008)--pioneering biochemist, educator and communicator
    Desmond J Tobin
    Center for Skin Sciences, School of Life Sciences, University of Bradford, Bradford, West Yorkshire, UK
    Exp Dermatol 17:579-83. 2008
    ..This obituary aims to contextualize the significant contributions made by this remarkable man to experimental dermatology...
  22. ncbi The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte-keratinocyte co-culture
    Suman K Singh
    Medical Biosciences Research, School of Life Sciences, University of Bradford, Bradford, West Yorkshire, UK
    Exp Dermatol 17:418-26. 2008
    ..In conclusion, this assay promises to significantly aid our investigations of the molecular basis of melanosome transfer and offers a new tool for the clinical evaluation of melanocyte modulators...
  23. ncbi Melatonin and the hair follicle
    Tobias W Fischer
    Department of Dermatology, University Hospital Schleswig Holstein, University of Lubeck, Lubeck, Germany
    J Pineal Res 44:1-15. 2008
    ....
  24. ncbi Modelling the buried human body environment in upland climes using three contrasting field sites
    Andrew S Wilson
    Department of Archaeological Sciences, University of Bradford, Bradford, West Yorkshire BD7 1DP, UK
    Forensic Sci Int 169:6-18. 2007
    ....
  25. ncbi NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth
    Ruth Schmidt-Ullrich
    Max Delbruck Center for Molecular Medicine, 13092 Berlin, Germany
    Development 133:1045-57. 2006
    ..The strongly decreased number of hair follicles observed in c(IkappaBalphaDeltaN) mice compared with tabby mice, indicates that additional signals, such as TROY, must regulate NF-kappaB activity in specific hair follicle subtypes...
  26. ncbi Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides
    Sobia Kauser
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire, BD7 1DP, UK
    FASEB J 20:882-95. 2006
    ..This study indicates that CRH peptides can differentially influence hair follicle melanocyte behavior not only via CRH-R1 signaling but also by complex cross-talk between CRH-R1 and CRH-R2...
  27. ncbi Dissecting the impact of chemotherapy on the human hair follicle: a pragmatic in vitro assay for studying the pathogenesis and potential management of hair follicle dystrophy
    Eniko Bodo
    Department of Dermatology, University Hospital Schleswig Holstein, University of Lubeck, D 23538 Lubeck, Ratzeburger Allee 160, Germany
    Am J Pathol 171:1153-67. 2007
    ..Thus, this novel system serves as a powerful yet pragmatic tool for dissecting and manipulating the impact of chemotherapy on the human HF...
  28. ncbi Corticotropin releasing hormone and the skin
    Andrzej Slominski
    Department of Pathology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    Front Biosci 11:2230-48. 2006
    ..The accumulated evidence indicates that cutaneous CRH is also a component of a local structure organized similarly to the hypothalamo-pituitary-adrenal axis...
  29. ncbi Does p53 regulate skin pigmentation by controlling proopiomelanocortin gene transcription?
    Andrzej Slominski
    Pigment Cell Res 20:307-8; author reply 309-10. 2007
  30. ncbi Neurotrophin-3 regulates mast cell functions in neonatal mouse skin
    Martin Metz
    Department of Dermatology, University Hospital Mainz, Mainz, Germany
    Exp Dermatol 13:273-81. 2004
    ..Our data suggest a role for NT-3 in the maturation of MCs, such as a TrkC-mediated stimulation of the differentiation of pre-existing, less mature MCs and/or by enhancing the migration of circulating MC precursors into the skin...
  31. ncbi Hair follicle pigmentation
    Andrzej Slominski
    Department of Pathology, University of Tennessee, Memphis, Tennessee 38163, USA
    J Invest Dermatol 124:13-21. 2005
    ..Melanin itself has a wide range of bioactivities that extend far beyond its determination of hair color...
  32. ncbi A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes
    Sobia Kauser
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire BD7 1DP, United Kingdom
    Endocrinology 146:532-43. 2005
    ..Thus, these findings suggest a role for these POMC peptides in regulating human hair follicle melanocyte differentiation...
  33. ncbi Plasticity and cytokinetic dynamics of the hair follicle mesenchyme: implications for hair growth control
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, UK
    J Invest Dermatol 120:895-904. 2003
    ..Modulation of these cell interchanges is likely to be important during clinically important hair follicle transformations, e.g. vellus-to-terminal and terminal-to-vellus during androgenetic alopecia...
  34. ncbi Regulation of human epidermal melanocyte biology by beta-endorphin
    Sobia Kauser
    Department of Biomedical Sciences, University of Bradford, West Yorkshire, UK
    J Invest Dermatol 120:1073-80. 2003
    ..In the absence of any data showing cross-talk between the mu-opiate receptor and the melanocortin-1 receptor, we conclude that the beta-endorphin/mu-opiate receptor system participates in the regulation of skin pigmentation...
  35. ncbi Characterization of hair follicle antigens targeted by the anti-hair follicle immune response
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, England
    J Investig Dermatol Symp Proc 8:176-81. 2003
    ..We are currently applying a more molecular approach (e.g., cDNA library screening) to identify hair follicle antigens truly associated with the onset of the disorder...
  36. ncbi Differential expression of a cutaneous corticotropin-releasing hormone system
    Andrzej Slominski
    Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center, 930 Madison Avenue, 5th Floor, Memphis, TN 38163, USA
    Endocrinology 145:941-50. 2004
    ..The adnexal location of CRH-R2 suggests a role for the receptor in hair growth. The differential interspecies CRH signaling expression pattern probably reflects adaptation to species-specific skin function determinants...
  37. ncbi Hair cycle and hair pigmentation: dynamic interactions and changes associated with aging
    Dominique Van Neste
    Skinterface, 9, rue du Sondart, B 7500 Tournai, Belgium
    Micron 35:193-200. 2004
    ..Such changes may not exclusively be related to improved hair growth itself but also to changes in natural hair color that makes the hair more visible with the method used to count hairs...
  38. ncbi beta-Endorphin as a regulator of human hair follicle melanocyte biology
    Sobia Kauser
    Department of Biomedical Sciences, University of Bradford, West Yorkshire, UK
    J Invest Dermatol 123:184-95. 2004
    ..These findings suggest a new regulatory role for beta-END in human HFM biology, providing a new research direction into the fundamental regulation of human hair pigmentation...
  39. ncbi Diphencyprone immunotherapy alters anti-hair follicle antibody status in patients with alopecia areata
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, West Yorkshire, BD7 1DP, England
    Eur J Dermatol 12:327-34. 2002
    ..Moreover, the presence/titer of anti-HF antibodies may be a marker of clinical disease activity or opportunity for spontaneous regrowth...
  40. ncbi Melanin pigmentation in mammalian skin and its hormonal regulation
    Andrzej Slominski
    Dept of Pathology, Suite 599, University of Tennessee Health Science Center, 930 Madison Avenue, Memphis, TN 38163, USA
    Physiol Rev 84:1155-228. 2004
    ..Indeed, the significance of melanogenesis extends beyond the mere assignment of a color trait...
  41. ncbi Serotoninergic and melatoninergic systems are fully expressed in human skin
    Andrzej Slominski
    Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    FASEB J 16:896-8. 2002
    ..NAS identity was confirmed further by LC/MS in keratinocytes. In conclusion, we provide evidence that the human skin expresses intrinsic serotonin and melatonin biosynthetic pathways...
  42. ncbi Expression of hypothalamic-pituitary-thyroid axis related genes in the human skin
    Andrzej Slominski
    Departments of Pathology, and Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
    J Invest Dermatol 119:1449-55. 2002
    ..We conclude that the expanding list of neuroendocrine elements expressed in the skin supports a strong role for this system in cutaneous biology...
  43. ncbi The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling
    Desmond J Tobin
    Department of Biomedical Sciences, University of Bradford, Bradford, England
    Am J Pathol 160:1807-21. 2002
    ..Principal target tissues that may contain protein substrate(s) for this cysteine protease include the developing hair cone, inner root sheath, anchoring apparatus of the telogen club, and organelles of lysosomal origin (eg, melanosomes)...
  44. ncbi Decreased photodamage and low incidence of non-melanoma skin cancer in 136 sun-exposed caucasian patients with vitiligo
    Karin U Schallreuter
    Institute for Pigmentary Disorders, Greifswald, Germany
    Dermatology 204:194-201. 2002
    ..However, scattered reports on low patient numbers documented no increased risk for sun-induced skin cancers in this disease...
  45. ncbi Tyrosine hydroxylase isoenzyme I is present in human melanosomes: a possible novel function in pigmentation
    Lee K Marles
    Clinical and Experimental Dermatology, Department of Biomedical Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK
    Exp Dermatol 12:61-70. 2003
    ..Our results support a direct function for tyrosine hydroxylase in the melanosome via a concerted action with tyrosinase to promote pigmentation...
  46. ncbi Melatonin in the skin: synthesis, metabolism and functions
    Andrzej Slominski
    Department of Pathology and Laboratory Medicine, University of Tennessee HSC, Memphis, TN, USA
    Trends Endocrinol Metab 19:17-24. 2008
    ..In this way, melatonin actions may counteract or buffer both environmental and endogenous stressors to maintain skin integrity...
  47. ncbi Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression
    Eva M J Peters
    Department of Dermatology, University Hospital Eppendorf, University of Hamburg, Germany
    J Histochem Cytochem 50:751-66. 2002
    ..In addition, differentiated c-Kit-IR melanocytes target the bulb, while non-c-Kit-IR melanoblasts invade the outer root sheath and bulge in fully developed hair follicles...
  48. ncbi Simple and rapid method to isolate and culture follicular papillae from human scalp hair follicles
    Markus Magerl
    Department of Biomedical Sciences, University of Bradford, Bradford, UK
    Exp Dermatol 11:381-5. 2002
    ..The method relies for its simplicity on the removal of the hair follicle papilla from the outside of the intact hair follicle rather than via internal manipulations from within the hair follicle...
  49. ncbi Cell type-specific functions of the lysosomal protease cathepsin L in the heart
    Daniel Spira
    Institut für Molekulare Medizin und Zellforschung, Albert Ludwigs Universitat Freiburg, D 79104 Freiburg, Germany
    J Biol Chem 282:37045-52. 2007
    ..We conclude that the DCM of Ctsl-/- mice is primarily caused by absence of the protease in cardiomyocytes, whereas the complex gross phenotype of Ctsl-deficient mice, i.e. the fur defect, results in additional stress to the heart...
  50. ncbi Mutant laboratory mice with abnormalities in pigmentation: annotated tables
    Motonobu Nakamura
    Department of Dermatology, University Hospital Eppendorf, University of Hamburg, Germany
    J Dermatol Sci 28:1-33. 2002
    ..In summary, this annotated table should serve as a useful reference for anyone interested in the molecular controls of pigmentation...
  51. ncbi Functional activity of serotoninergic and melatoninergic systems expressed in the skin
    Andrzej Slominski
    Department of Pathology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Cell Physiol 196:144-53. 2003
    ..Thus, skin cells represent a true target for the products of the serotoninergic/melatoninergic cutaneous pathway with their actions modulating cell proliferation or viability...
  52. ncbi Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin
    Eva Milena J Peters
    Department of Internal Medicine, Charite University Medicine, Berlin, Germany
    Brain Behav Immun 19:252-62. 2005
    ..Thus, neuronal plasticity and increased neuro-immune interaction occur under stress and may alter inflammatory skin diseases and trophic functions in the skin where neurogenic inflammation plays a part...
  53. ncbi Resistance of degraded hair shafts to contaminant DNA
    M Thomas P Gilbert
    Henry Wellcome Ancient Biomolecules Centre, Department of Zoology, University of Oxford, South Parks Rd, Oxford OX1 3PS, UK
    Forensic Sci Int 156:208-12. 2006
    ..Therefore, hair samples represent an important and underestimated source of DNA in both forensic and ancient DNA studies...
  54. ncbi Premature termination of hair follicle morphogenesis and accelerated hair follicle cycling in Iasi congenital atrichia (fzica) mice points to fuzzy as a key element of hair cycle control
    Lars Mecklenburg
    Department of Pathobiology, College of Veterinary Medicine, Texas A and M University, College Station, TX 77843 4467, USA
    Exp Dermatol 14:561-70. 2005
    ..Our data show that fuzzy is involved in controlling both catagen and anagen initiation, designating fuzzy an exciting target for characterizing the intracutaneous oscillator system that drives hair follicle cycling...
  55. ncbi The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling
    Thomas Reinheckel
    Institute of Molecular Medicine and Cell Research, Albert Ludwigs University, 79106 Freiburg, Germany
    J Cell Sci 118:3387-95. 2005
    ....
  56. ncbi Limitations of human occipital scalp hair follicle organ culture for studying the effects of minoxidil as a hair growth enhancer
    Markus Magerl
    Department of Biomedical Sciences, University of Bradford, Bradford, UK
    Exp Dermatol 13:635-42. 2004
    ....
  57. ncbi On the role of melatonin in skin physiology and pathology
    Andrzej Slominski
    Department of Pathology and Laboratory Medicine, Health Science Center, University of Tennessee, Memphis, TN 38103, USA
    Endocrine 27:137-48. 2005
    ..Furthermore, melatonin could have a role in protection against solar radiation or even in the management of skin diseases...
  58. ncbi The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
    Andrzej Slominski
    Department of Pathology, University of Tennessee, Memphis, Tennessee, USA
    FASEB J 19:176-94. 2005
    ..Slominski, A. J., Wortsman, J., Tobin, D. J. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun...
  59. ncbi Ancient mitochondrial DNA from hair
    M Thomas P Gilbert
    Curr Biol 14:R463-4. 2004
  60. ncbi Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology
    Markus Bohm
    Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Munster, Germany
    J Invest Dermatol 126:1966-75. 2006
    ..These findings should improve our understanding of skin physiology and pathophysiology and may offer novel strategies with MCs as future therapeutics for skin diseases...
  61. ncbi Activation of the Mitf promoter by lipid-stimulated activation of p38-stress signalling to CREB
    Bidisha Saha
    Department of Cellular Biochemistry, Indian Institute of Chemical Biology, 4, Raja S C Mullick Road, Jadavpur, Kolkata 700 032, India
    Pigment Cell Res 19:595-605. 2006
    ..The results are relevant for the regulation of melanocytes by Mitf, but also raise the possibility that lipid mediated activation of p38 signalling may represent a potential therapy for vitiligo...
  62. ncbi Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice
    Sanja Pavlovic
    Psycho Neuro Immunology, Center for Internal Medicine and Dermatology, Neuroscience Research Center, Charite University Medicine, Campus Mitte, Berlin, Germany
    J Invest Dermatol 128:434-46. 2008
    ....