Stephen Tisch

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Effect of electrode contact location on clinical efficacy of pallidal deep brain stimulation in primary generalised dystonia
    S Tisch
    Unit of Functional Neurosurgery, Sobell Department, Institute of Neurology, University College London, Box 146, 8 11 Queen Square, London WC1N 3BG, UK
    J Neurol Neurosurg Psychiatry 78:1314-9. 2007
  2. ncbi request reprint The physiological effects of pallidal deep brain stimulation in dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience, Institute of Neurology, London WC1N 3BG, UK
    IEEE Trans Neural Syst Rehabil Eng 15:166-72. 2007
  3. ncbi request reprint Pallidal stimulation modifies after-effects of paired associative stimulation on motor cortex excitability in primary generalised dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Box 146 8 11 Queen Square, London WC1N 3BG, UK
    Exp Neurol 206:80-5. 2007
  4. ncbi request reprint Cortical evoked potentials from pallidal stimulation in patients with primary generalized dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:265-73. 2008
  5. pmc Deep brain stimulation effects in dystonia: time course of electrophysiological changes in early treatment
    Diane Ruge
    Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 26:1913-21. 2011
  6. ncbi request reprint Excessive synchronization of basal ganglia neurons at 20 Hz slows movement in Parkinson's disease
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Exp Neurol 205:214-21. 2007
  7. ncbi request reprint Intra-operative recordings of local field potentials can help localize the subthalamic nucleus in Parkinson's disease surgery
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Exp Neurol 198:214-21. 2006
  8. ncbi request reprint Changes in blink reflex excitability after globus pallidus internus stimulation for dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 21:1650-5. 2006
  9. ncbi request reprint Deep brain stimulation of the subthalamic nucleus: a two-edged sword
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Curr Biol 16:R952-3. 2006
  10. doi request reprint Effects of contact location and voltage amplitude on speech and movement in bilateral subthalamic nucleus deep brain stimulation
    Elina Tripoliti
    Unit of Functional Neurosurgery, Sobell Department, Institute of Neurology, London, United Kingdom
    Mov Disord 23:2377-83. 2008

Collaborators

Detail Information

Publications23

  1. pmc Effect of electrode contact location on clinical efficacy of pallidal deep brain stimulation in primary generalised dystonia
    S Tisch
    Unit of Functional Neurosurgery, Sobell Department, Institute of Neurology, University College London, Box 146, 8 11 Queen Square, London WC1N 3BG, UK
    J Neurol Neurosurg Psychiatry 78:1314-9. 2007
    ..To determine the effect of electrode contact location on efficacy of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) for primary generalised dystonia (PGD). Subjects and..
  2. ncbi request reprint The physiological effects of pallidal deep brain stimulation in dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience, Institute of Neurology, London WC1N 3BG, UK
    IEEE Trans Neural Syst Rehabil Eng 15:166-72. 2007
    ....
  3. ncbi request reprint Pallidal stimulation modifies after-effects of paired associative stimulation on motor cortex excitability in primary generalised dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Box 146 8 11 Queen Square, London WC1N 3BG, UK
    Exp Neurol 206:80-5. 2007
    ..To determine the effect of globus pallidus internus (GPi) deep brain stimulation (DBS) on motor cortex plasticity in patients with primary generalised dystonia...
  4. ncbi request reprint Cortical evoked potentials from pallidal stimulation in patients with primary generalized dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
    Mov Disord 23:265-73. 2008
    ..Because the EP is larger and more consistently present with stimulation of posteroventral GPi than GPe, it may provide a physiological tool to identify contacts within the optimal surgical target...
  5. pmc Deep brain stimulation effects in dystonia: time course of electrophysiological changes in early treatment
    Diane Ruge
    Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 26:1913-21. 2011
    ..Clinical benefit is delayed because engrams of abnormal movement persist and take time to normalize. Our observations suggest that plasticity may be a driver of long-term therapeutic effects of deep brain stimulation in dystonia...
  6. ncbi request reprint Excessive synchronization of basal ganglia neurons at 20 Hz slows movement in Parkinson's disease
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Exp Neurol 205:214-21. 2007
    ..This effect was frequency selective. The current data provide proof of the principle that excessive beta synchrony within the basal ganglia-cortical loop may contribute to the slowing of movements in Parkinson's disease...
  7. ncbi request reprint Intra-operative recordings of local field potentials can help localize the subthalamic nucleus in Parkinson's disease surgery
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London WCIN 3BG, UK
    Exp Neurol 198:214-21. 2006
    ..Functional physiological localization of STN by the on-line spectral analysis of LFPs is quick to perform and may provide information directly relevant to the position of the electrode contact actually used for DBS...
  8. ncbi request reprint Changes in blink reflex excitability after globus pallidus internus stimulation for dystonia
    Stephen Tisch
    Unit of Functional Neurosurgery, Sobell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, London, United Kingdom
    Mov Disord 21:1650-5. 2006
    ..We conclude that GPi DBS for PTD results in functional reorganization of the nervous system, which includes a long-term increase in brainstem inhibition...
  9. ncbi request reprint Deep brain stimulation of the subthalamic nucleus: a two-edged sword
    Chiung Chu Chen
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Curr Biol 16:R952-3. 2006
  10. doi request reprint Effects of contact location and voltage amplitude on speech and movement in bilateral subthalamic nucleus deep brain stimulation
    Elina Tripoliti
    Unit of Functional Neurosurgery, Sobell Department, Institute of Neurology, London, United Kingdom
    Mov Disord 23:2377-83. 2008
    ....
  11. ncbi request reprint Sensory timing cues improve akinesia of grasping movements in Parkinson's disease: a comparison to the effects of subthalamic nucleus stimulation
    Dennis A Nowak
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 21:166-72. 2006
    ..This implies that subthalamic nucleus stimulation produces a generalized upregulation in the gain of all components of a movement without the subtlety of focused control that is required to normalize performance...
  12. ncbi request reprint Cortico-cortical coupling in Parkinson's disease and its modulation by therapy
    Paul Silberstein
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Brain 128:1277-91. 2005
    ..This mechanistic similarity may underscore the strong clinical correlation between the therapeutic effects of these treatment modalities...
  13. ncbi request reprint The beneficial effects of subthalamic nucleus stimulation on manipulative finger force control in Parkinson's disease
    Dennis A Nowak
    Sobell Department of Motor Neuroscience and Movements Disorders, Institute of Neurology, University of London, London, UK
    Exp Neurol 193:427-36. 2005
    ..STN stimulation enables Parkinson subjects to scale grip force more accurately to the loads arising from voluntary manipulation of hand-held objects...
  14. doi request reprint Oscillatory activity in the pedunculopontine area of patients with Parkinson's disease
    Alexandros G Androulidakis
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, Queen Square, London, UK
    Exp Neurol 211:59-66. 2008
    ..The subcortical oscillations are coupled to cortical alpha activity and possibly allied to motor related attentional processes...
  15. doi request reprint Stereotactic localization of the human pedunculopontine nucleus: atlas-based coordinates and validation of a magnetic resonance imaging protocol for direct localization
    Ludvic Zrinzo
    Unit of Functional Neurosurgery, Institute of Neurology, University College London, UK
    Brain 131:1588-98. 2008
    ..Direct MRI localization may allow greater individual accuracy than that afforded by atlas-based coordinates when localizing the human PPN and may be relevant to groups evaluating the clinical role of PPN DBS...
  16. ncbi request reprint Can chronic subthalamic nucleus stimulation induce de novo tremor in Parkinson's disease?
    Stephane Thobois
    Sobell Department of Motor Neurosciences and Movement Disorders, Unit of Functional Neurosurgery, Institute of Neurology, London, United Kingdom
    Mov Disord 20:1066-9. 2005
    ..We report on the cases of 3 patients who developed such modification of their parkinsonian symptomatology. Physiopathological hypotheses are discussed...
  17. pmc Pallidal stimulation for primary generalised dystonia: effect on cognition, mood and quality of life
    Marjan Jahanshahi
    Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK
    J Neurol 261:164-73. 2014
    ..The dissociation between GPi-DBS improving dystonia, but not having a significant positive impact on the patients' QoL, warrants further investigation...
  18. ncbi request reprint The basal ganglia: anatomy, physiology, and pharmacology
    Stephen Tisch
    Sobell Department of Motor Neuroscience and Movement Disorders Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
    Psychiatr Clin North Am 27:757-99. 2004
    ..Further work will elucidate this to a greater extent, but for now, it is clear that the basal ganglia form an important nexus in the binding of cognitive, limbic, and motor information into thought and action...
  19. ncbi request reprint Variability of the subthalamic nucleus: the case for direct MRI guided targeting
    K Ashkan
    Functional Neurosurgery Unit, Institute of Neurology, London, UK
    Br J Neurosurg 21:197-200. 2007
    ..The coordinates of the directly visualised STN were significantly different from those of the atlas target. Variability of the position of the STN may render direct visualisation a more accurate means of targeting this nucleus...
  20. pmc Suppression of beta oscillations in the subthalamic nucleus following cortical stimulation in humans
    L M F Doyle Gaynor
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK
    Eur J Neurosci 28:1686-95. 2008
    ..The results may have implications for mechanisms underlying the reported therapeutic benefits of cortical stimulation...
  21. ncbi request reprint Changes in forearm reciprocal inhibition following pallidal stimulation for dystonia
    S Tisch
    obell Department Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square London, United Kingdom
    Neurology 66:1091-3. 2006
    ..The authors conclude that pallidal DBS for dystonia results in functional reorganization of the nervous system, which includes a long-term increase in spinal inhibition...
  22. ncbi request reprint Severe tongue protrusion dystonia: clinical syndromes and possible treatment
    S A Schneider
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, UCL, London WC1N 3BG, UK
    Neurology 67:940-3. 2006
    ..Tongue protrusion dystonia is often unresponsive to oral drugs but may benefit from botulinum toxin injections into the genioglossus muscle. Bilateral deep brain pallidal stimulation was beneficial in two cases...
  23. ncbi request reprint Activation of the subthalamic region during emotional processing in Parkinson disease
    A A Kühn
    Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, WC1N 3BG, UK
    Neurology 65:707-13. 2005
    ..To elucidate the involvement of the human subthalamic nucleus (STN) region in the processing or transmission of emotional information...