D I Thurnham

Summary

Affiliation: University of Ulster
Country: UK

Publications

  1. doi request reprint Studies on meso-zeaxanthin for potential toxicity and mutagenicity
    David I Thurnham
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Food Chem Toxicol 59:455-63. 2013
  2. pmc A retrospective investigation of thiamin and energy intakes following an outbreak of beriberi in The Gambia
    David I Thurnham
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, UK
    Nutrients 3:135-51. 2011
  3. ncbi request reprint Effects of subclinical infection on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: meta-analysis
    D I Thurnham
    Northern Ireland Centre for Food and Health, Faculty of Life and Health Sciences, University of Ulster, Coleraine, UK
    Lancet 362:2052-8. 2003
  4. ncbi request reprint Using plasma acute-phase protein concentrations to interpret nutritional biomarkers in apparently healthy HIV-1-seropositive Kenyan adults
    David I Thurnham
    Northern Ireland Centre for Food and Health, Cromore Road, University of Ulster, Coleraine BT52 1SA, UK
    Br J Nutr 100:174-82. 2008
  5. doi request reprint A supplementation study in human subjects with a combination of meso-zeaxanthin, (3R,3'R)-zeaxanthin and (3R,3'R,6'R)-lutein
    David I Thurnham
    Northern Ireland Centre for Food and Health NICHE, University of Ulster, Coleraine BT51 4LA, UK
    Br J Nutr 100:1307-14. 2008
  6. ncbi request reprint Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis
    David I Thurnham
    Northern Ireland Centre for Food amp Health, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 92:546-55. 2010
  7. ncbi request reprint Nutritional factors and visual function in premature infants
    V C Jewell
    Northern Ireland Centre for Diet and Health, University of Ulster, Coleraine, UK
    Proc Nutr Soc 60:171-8. 2001
  8. ncbi request reprint Antioxidants and lipoprotein metabolism
    M Chopra
    Northern Ireland Centre for Diet and Health, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Proc Nutr Soc 58:663-71. 1999
  9. ncbi request reprint Effect of improved vitamin A status on response to iron supplementation in Pakistani infants
    C A Northrop-Clewes
    Department of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 64:694-9. 1996
  10. ncbi request reprint Frequency of fruit and vegetable consumption and blood antioxidants in the Caerphilly cohort of older men
    J J Strain
    Northern Ireland Centre for Diet and Health NICHE, University of Ulster, Coleraine, Co Londonderry, UK
    Eur J Clin Nutr 54:828-33. 2000

Detail Information

Publications22

  1. doi request reprint Studies on meso-zeaxanthin for potential toxicity and mutagenicity
    David I Thurnham
    Northern Ireland Centre for Food and Health, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Food Chem Toxicol 59:455-63. 2013
    ..MZ did not cause any increase in the mean number of revertants/plate with any bacterial strain, with or without microsomal enzymes, and was therefore unlikely to be mutagenic...
  2. pmc A retrospective investigation of thiamin and energy intakes following an outbreak of beriberi in The Gambia
    David I Thurnham
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, UK
    Nutrients 3:135-51. 2011
    ..In contrast, the higher energy intake of adults in the BBC may have enabled them to continue working, thus increasing demands for thiamin and inducing the earlier onset of beriberi...
  3. ncbi request reprint Effects of subclinical infection on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: meta-analysis
    D I Thurnham
    Northern Ireland Centre for Food and Health, Faculty of Life and Health Sciences, University of Ulster, Coleraine, UK
    Lancet 362:2052-8. 2003
    ..We aimed to estimate vitamin A deficiency more accurately by measuring changes in plasma retinol and acute-phase proteins associated with subclinical infection or convalescence...
  4. ncbi request reprint Using plasma acute-phase protein concentrations to interpret nutritional biomarkers in apparently healthy HIV-1-seropositive Kenyan adults
    David I Thurnham
    Northern Ireland Centre for Food and Health, Cromore Road, University of Ulster, Coleraine BT52 1SA, UK
    Br J Nutr 100:174-82. 2008
    ..The method does now need to be tested in other populations...
  5. doi request reprint A supplementation study in human subjects with a combination of meso-zeaxanthin, (3R,3'R)-zeaxanthin and (3R,3'R,6'R)-lutein
    David I Thurnham
    Northern Ireland Centre for Food and Health NICHE, University of Ulster, Coleraine BT51 4LA, UK
    Br J Nutr 100:1307-14. 2008
    ....
  6. ncbi request reprint Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis
    David I Thurnham
    Northern Ireland Centre for Food amp Health, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 92:546-55. 2010
    ..The World Health Organization recommends serum ferritin concentrations as the best indicator of iron deficiency (ID). Unfortunately, ferritin increases with infections; hence, the prevalence of ID is underestimated...
  7. ncbi request reprint Nutritional factors and visual function in premature infants
    V C Jewell
    Northern Ireland Centre for Diet and Health, University of Ulster, Coleraine, UK
    Proc Nutr Soc 60:171-8. 2001
    ..The biochemical mechanisms which mediate the transport of the macular carotenoids into the eye are not known, but tubulin has been identified as the major carotenoid-binding protein, and may play a role in the physiology of the macula...
  8. ncbi request reprint Antioxidants and lipoprotein metabolism
    M Chopra
    Northern Ireland Centre for Diet and Health, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Proc Nutr Soc 58:663-71. 1999
    ..In particular, the present paper will review the available literature on the affect of antioxidant supplementation on lipoprotein oxidation, and hence metabolism of LDL in human subjects...
  9. ncbi request reprint Effect of improved vitamin A status on response to iron supplementation in Pakistani infants
    C A Northrop-Clewes
    Department of Biomedical Sciences, University of Ulster, Coleraine, United Kingdom
    Am J Clin Nutr 64:694-9. 1996
    ..These conclusions should now be confirmed with an intervention study to show that the benefits of vitamin A on iron status are due to reduced levels of infection...
  10. ncbi request reprint Frequency of fruit and vegetable consumption and blood antioxidants in the Caerphilly cohort of older men
    J J Strain
    Northern Ireland Centre for Diet and Health NICHE, University of Ulster, Coleraine, Co Londonderry, UK
    Eur J Clin Nutr 54:828-33. 2000
    ....
  11. ncbi request reprint Nonalcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoid concentrations
    M Chopra
    Northern Ireland Center for Diet and Health NICHE, University of Ulster, Coleraine BT52 1SA, Northern Ireland
    Clin Chem 46:1162-70. 2000
    ....
  12. ncbi request reprint A European carotenoid database to assess carotenoid intakes and its use in a five-country comparative study
    Y Carroll
    Northern Ireland Centre for Diet and Health, University of Ulster, Coleraine BT52 1SA, UK
    Br J Nutr 85:499-507. 2001
    ..The results show that within Europe there are differences in the specific intake of some carotenoids which are related to different foods consumed by people in different countries...
  13. ncbi request reprint Intestinal absorption of beta-carotene, lycopene and lutein in men and women following a standard meal: response curves in the triacylglycerol-rich lipoprotein fraction
    M E O'Neill
    Northern Ireland Centre for Diet and Health, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Br J Nutr 79:149-59. 1998
    ..In conclusion, large inter-subject variation in TRL carotene uptake precluded any differences between sexes but surprising intra-subject consistency was observed in TRL beta-carotene uptake of three subjects...
  14. ncbi request reprint Innate immunity, gut integrity, and vitamin A in Gambian and Indian infants
    D I Thurnham
    Northern Ireland Centre for Diet and Health, School of Biomedical Sciences, University of Ulster, Coleraine BT 52 1SA, Northern Ireland
    J Infect Dis 182:S23-8. 2000
    ..All VA-treated groups had more rapid improvement in gut integrity than the placebo groups, but no group had gut integrity normalized by Western standards. The data suggest that VA status may influence gut integrity...
  15. ncbi request reprint The effect of vitamin A on epithelial integrity
    F S McCullough
    Northern Ireland Centre for Diet and Health NICHE, University of Ulster, Coleraine, UK
    Proc Nutr Soc 58:289-93. 1999
    ..In summary, the response of the eye to vitamin A supplementation is well established; the present review highlights some of the more recent observations examining the effects of vitamin A...
  16. ncbi request reprint A comparison of lutein and zeaxanthin concentrations in formula and human milk samples from Northern Ireland mothers
    V C Jewell
    Northern Ireland Centre for Food and Health, University of Ulster, Coleraine BT52 1SA, Northern Ireland
    Eur J Clin Nutr 58:90-7. 2004
    ..The amounts of these carotenoids consumed by premature infants are not known...
  17. ncbi request reprint Optimal nutrition: vitamin A and the carotenoids
    D I Thurnham
    Northern Ireland Centre for Diet and Health, University of Ulster, Coleraine, UK
    Proc Nutr Soc 58:449-57. 1999
    ..Some carotenoids are important as vitamin A precursors, but the physiological importance of their antioxidant properties is not known and consequently the amount needed for optimal nutrition is uncertain...
  18. ncbi request reprint Lack of influence of red palm oil on severity of malaria infection in pre-school Nigerian children
    K A Cooper
    Northern Ireland Centre for Diet and Health, University of Ulster, Coleraine BT52 1SA, UK
    Trans R Soc Trop Med Hyg 96:216-23. 2002
    ..e., there was some evidence that RPO usage protected against malaria, and other dietary indices generally indicated that better nutritional status was associated with a lower severity of malaria...
  19. ncbi request reprint Dialysis and gel filtration of isolated low density lipoproteins do not cause a significant loss of low density lipoprotein tocopherol and carotenoid concentration
    M Chopra
    NICHe, School of Biomedical Sciences, University of Ulster, Northern Ireland, United Kingdom
    Lipids 36:205-9. 2001
    ..In summary, immediate dialysis of freshly isolated LDL in the presence of 10 micromol/L EDTA does not cause any major loss in the concentration of tocopherol and most carotenoids...
  20. ncbi request reprint Impact of health service provision on mothers and infants in a rural village in North West Frontier Province, Pakistan
    C A Northrop-Clewes
    Northern Ireland Centre for Diet and Health, University of Ulster, Coleraine
    Public Health Nutr 1:51-9. 1998
    ..The objective of this paper is to examine the impact of the Health Service Research Project of the Pakistan Medical Research Council (PMRC) on mothers and infants in Budhni village, North West Frontier Province (NWFP), Pakistan...
  21. ncbi request reprint Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers
    M Chopra
    Northern Ireland Centre for Diet and Health, School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, Northern Ireland BT52 1SA, United Kingdom
    Clin Chem 46:1818-29. 2000
    ..The aim of this study was to determine the carotenoid response of smokers and nonsmokers to increased intake of 300-400 g of vegetables and its effect on LDL oxidation...
  22. pmc Micronutrients and immune function: some recent developments
    D I Thurnham
    Human Nutrition Research Group, School of Biomedical Sciences, University of Ulster, Coleraine, UK
    J Clin Pathol 50:887-91. 1997
    ..Low plasma ascorbate may assist the removal of iron from plasma and low iron concentrations appear to increase the cytotoxicity of macrophages...