J R Thorpe

Summary

Affiliation: University of Sussex
Country: UK

Publications

  1. ncbi request reprint Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain
    J R Thorpe
    Electron Microscope and FACS Laboratory, School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Histochem Cytochem 49:97-108. 2001
  2. ncbi request reprint Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias
    Julian R Thorpe
    Electron Microscope Division, The Sussex Centre for Advanced Microscopy, School of Life Sciences, University of Sussex, Brighton, UK
    Neurobiol Dis 17:237-49. 2004
  3. pmc Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy
    Julian R Thorpe
    The Sussex Centre for Advanced Microscopy, University of Sussex, Falmer, Brighton, East Sussex, BN1 9QG, UK
    J Neural Transm 115:1661-71. 2008
  4. pmc Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease
    Sabrina Mosaheb
    Electron Microscope Division, Sussex Centre for Advanced Microscopy, School of Life Sciences, University of Sussex, Brighton, UK
    Acta Neuropathol 110:360-8. 2005

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain
    J R Thorpe
    Electron Microscope and FACS Laboratory, School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Histochem Cytochem 49:97-108. 2001
    ....
  2. ncbi request reprint Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias
    Julian R Thorpe
    Electron Microscope Division, The Sussex Centre for Advanced Microscopy, School of Life Sciences, University of Sussex, Brighton, UK
    Neurobiol Dis 17:237-49. 2004
    ..This may be a unifying, contributory factor towards neuronal death in these dementias...
  3. pmc Fine structural analysis of the neuronal inclusions of frontotemporal lobar degeneration with TDP-43 proteinopathy
    Julian R Thorpe
    The Sussex Centre for Advanced Microscopy, University of Sussex, Falmer, Brighton, East Sussex, BN1 9QG, UK
    J Neural Transm 115:1661-71. 2008
    ....
  4. pmc Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease
    Sabrina Mosaheb
    Electron Microscope Division, Sussex Centre for Advanced Microscopy, School of Life Sciences, University of Sussex, Brighton, UK
    Acta Neuropathol 110:360-8. 2005
    ..These observations indicate that abnormal protein aggregation follows separate pathways in different neuronal compartments of NIFID...