Catherine A Thornton

Summary

Affiliation: University of Wales
Country: UK

Publications

  1. ncbi Innate and adaptive immune pathways to tolerance
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Nestle Nutr Workshop Ser Pediatr Program 64:45-57; discussion 57-61, 251-7. 2009
  2. ncbi Immunology of pregnancy
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea SA2 8PP, UK
    Proc Nutr Soc 69:357-65. 2010
  3. ncbi The hygiene hypothesis revisited: role of materno-fetal interactions
    Catherine A Thornton
    Institute of Life Science, Swansea University, Wales, UK
    Curr Allergy Asthma Rep 10:444-52. 2010
  4. ncbi Human mid-gestation amniotic fluid contains interleukin-16 bioactivity
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea
    Immunology 126:543-51. 2009
  5. ncbi Phenotypic analysis of circulating dendritic cells during the second half of human gestation
    Judith A Holloway
    School of Medicine, University of Southampton, Southampton, UK
    Pediatr Allergy Immunol 20:119-25. 2009
  6. ncbi The effect of labor on neonatal T-cell phenotype and function
    Catherine A Thornton
    Infection, Inflammation and Repair, School of Medicine, University of Southampton, UK
    Pediatr Res 54:120-4. 2003
  7. ncbi Thymic stromal lymphopoietin is present in human breast milk
    Trisha V Macfarlane
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Pediatr Allergy Immunol 21:e454-6. 2010
  8. ncbi Analysis of quantum dot fluorescence stability in primary blood mononuclear cells
    Huw D Summers
    Multidisciplinary Nanotechnology Center, School of Engineering, Swansea University, Swansea SA28PP, United Kingdom
    Cytometry A 77:933-9. 2010
  9. ncbi Dietary supplementation with lactobacilli and bifidobacteria is well tolerated and not associated with adverse events during late pregnancy and early infancy
    Stephen J Allen
    The School of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK
    J Nutr 140:483-8. 2010
  10. ncbi Functional maturation of CD4+CD25+CTLA4+CD45RA+ T regulatory cells in human neonatal T cell responses to environmental antigens/allergens
    Catherine A Thornton
    School of Medicine, University of Wales, Swansea, United Kingdom
    J Immunol 173:3084-92. 2004

Collaborators

Detail Information

Publications13

  1. ncbi Innate and adaptive immune pathways to tolerance
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Nestle Nutr Workshop Ser Pediatr Program 64:45-57; discussion 57-61, 251-7. 2009
    ..Current paradigms of immunity and tolerance in relation to the development of allergy relate to the interplay between innate and immunoregulatory mechanisms...
  2. ncbi Immunology of pregnancy
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea SA2 8PP, UK
    Proc Nutr Soc 69:357-65. 2010
    ..Understanding the underlying mechanisms of any positive effect on disease outcomes should reveal further novel strategies for disease prevention...
  3. ncbi The hygiene hypothesis revisited: role of materno-fetal interactions
    Catherine A Thornton
    Institute of Life Science, Swansea University, Wales, UK
    Curr Allergy Asthma Rep 10:444-52. 2010
    ..Thus, we seem to be at the dawn of a new incarnation of the hygiene hypothesis in which the pregnant woman's inflammatory response is crucial to determining the child's likelihood of developing allergic disease...
  4. ncbi Human mid-gestation amniotic fluid contains interleukin-16 bioactivity
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea
    Immunology 126:543-51. 2009
    ..IL-16 might have an important role in the early development of the human immune system and/or in regulating fetal and maternal immunological responsiveness during pregnancy...
  5. ncbi Phenotypic analysis of circulating dendritic cells during the second half of human gestation
    Judith A Holloway
    School of Medicine, University of Southampton, Southampton, UK
    Pediatr Allergy Immunol 20:119-25. 2009
    ..Thus, immaturity of cord blood DCs is likely to arise as a consequence of decreased ability to take up antigen (at least via IgG-mediated mechanisms) and reduced provision of co-stimulation...
  6. ncbi The effect of labor on neonatal T-cell phenotype and function
    Catherine A Thornton
    Infection, Inflammation and Repair, School of Medicine, University of Southampton, UK
    Pediatr Res 54:120-4. 2003
    ....
  7. ncbi Thymic stromal lymphopoietin is present in human breast milk
    Trisha V Macfarlane
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Pediatr Allergy Immunol 21:e454-6. 2010
    ..001) at 3-5 days than at 11-26 days postpartum. The potential role of breast milk TSLP in the development of immune function within the neonatal gastrointestinal tract and the development of allergy in childhood remain to be determined...
  8. ncbi Analysis of quantum dot fluorescence stability in primary blood mononuclear cells
    Huw D Summers
    Multidisciplinary Nanotechnology Center, School of Engineering, Swansea University, Swansea SA28PP, United Kingdom
    Cytometry A 77:933-9. 2010
    ..These results provide phenomenological descriptions of the evolving QD fluorescence within live cells with associated analytical equations that allow quantitative assessment of QD-based assays...
  9. ncbi Dietary supplementation with lactobacilli and bifidobacteria is well tolerated and not associated with adverse events during late pregnancy and early infancy
    Stephen J Allen
    The School of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK
    J Nutr 140:483-8. 2010
    ..None of the AE were attributed to the intervention. Our findings support the safe use of this consortium of organisms during pregnancy and early infancy...
  10. ncbi Functional maturation of CD4+CD25+CTLA4+CD45RA+ T regulatory cells in human neonatal T cell responses to environmental antigens/allergens
    Catherine A Thornton
    School of Medicine, University of Wales, Swansea, United Kingdom
    J Immunol 173:3084-92. 2004
    ....
  11. ncbi Expression of CD21 and CD23 during human fetal development
    Catherine A Thornton
    Allergy and Inflammation Sciences, School of Medicine, University of Southampton, SO16 6YD, UK
    Pediatr Res 52:245-50. 2002
    ..However the abundance of CD21-positive T cells could alter the T- and B-cell interaction necessary for IgE switching by B cells and, thereby, especially with impaired IL-4 production, limit IgE production...
  12. ncbi Protocol of the baseline assessment for the Environments for Healthy Living (EHL) Wales cohort study
    Rebecca A Hill
    School of Medicine, Swansea University, Singleton Park, Swansea, UK
    BMC Public Health 10:150. 2010
    ..The baseline assessment will focus on birth outcomes and maternal and infant health...
  13. ncbi Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk
    Emmanuel LeBouder
    Infection and Immunity, Department of Medical Biochemistry and Immunology, Cardiff University College of Medicine, Heath Park, Cardiff CF14 4XX, Wales, UK
    J Immunol 176:3742-52. 2006
    ..This in turn suggests the existence of novel mechanisms regulating TLR activation...