Catherine A Thornton

Summary

Affiliation: University of Wales
Country: UK

Publications

  1. doi request reprint Innate and adaptive immune pathways to tolerance
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Nestle Nutr Workshop Ser Pediatr Program 64:45-57; discussion 57-61, 251-7. 2009
  2. doi request reprint Immunology of pregnancy
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea SA2 8PP, UK
    Proc Nutr Soc 69:357-65. 2010
  3. doi request reprint The hygiene hypothesis revisited: role of materno-fetal interactions
    Catherine A Thornton
    Institute of Life Science, Swansea University, Wales, UK
    Curr Allergy Asthma Rep 10:444-52. 2010
  4. pmc Human mid-gestation amniotic fluid contains interleukin-16 bioactivity
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea
    Immunology 126:543-51. 2009
  5. doi request reprint Phenotypic analysis of circulating dendritic cells during the second half of human gestation
    Judith A Holloway
    School of Medicine, University of Southampton, Southampton, UK
    Pediatr Allergy Immunol 20:119-25. 2009
  6. ncbi request reprint The effect of labor on neonatal T-cell phenotype and function
    Catherine A Thornton
    Infection, Inflammation and Repair, School of Medicine, University of Southampton, UK
    Pediatr Res 54:120-4. 2003
  7. doi request reprint Thymic stromal lymphopoietin is present in human breast milk
    Trisha V Macfarlane
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Pediatr Allergy Immunol 21:e454-6. 2010
  8. doi request reprint Analysis of quantum dot fluorescence stability in primary blood mononuclear cells
    Huw D Summers
    Multidisciplinary Nanotechnology Center, School of Engineering, Swansea University, Swansea SA28PP, United Kingdom
    Cytometry A 77:933-9. 2010
  9. ncbi request reprint Expression of CD21 and CD23 during human fetal development
    Catherine A Thornton
    Allergy and Inflammation Sciences, School of Medicine, University of Southampton, SO16 6YD, UK
    Pediatr Res 52:245-50. 2002
  10. doi request reprint Dietary supplementation with lactobacilli and bifidobacteria is well tolerated and not associated with adverse events during late pregnancy and early infancy
    Stephen J Allen
    The School of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK
    J Nutr 140:483-8. 2010

Collaborators

Detail Information

Publications15

  1. doi request reprint Innate and adaptive immune pathways to tolerance
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Nestle Nutr Workshop Ser Pediatr Program 64:45-57; discussion 57-61, 251-7. 2009
    ..Current paradigms of immunity and tolerance in relation to the development of allergy relate to the interplay between innate and immunoregulatory mechanisms...
  2. doi request reprint Immunology of pregnancy
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea SA2 8PP, UK
    Proc Nutr Soc 69:357-65. 2010
    ..Understanding the underlying mechanisms of any positive effect on disease outcomes should reveal further novel strategies for disease prevention...
  3. doi request reprint The hygiene hypothesis revisited: role of materno-fetal interactions
    Catherine A Thornton
    Institute of Life Science, Swansea University, Wales, UK
    Curr Allergy Asthma Rep 10:444-52. 2010
    ..Thus, we seem to be at the dawn of a new incarnation of the hygiene hypothesis in which the pregnant woman's inflammatory response is crucial to determining the child's likelihood of developing allergic disease...
  4. pmc Human mid-gestation amniotic fluid contains interleukin-16 bioactivity
    Catherine A Thornton
    Institute of Life Science, School of Medicine, Swansea University, Swansea
    Immunology 126:543-51. 2009
    ..IL-16 might have an important role in the early development of the human immune system and/or in regulating fetal and maternal immunological responsiveness during pregnancy...
  5. doi request reprint Phenotypic analysis of circulating dendritic cells during the second half of human gestation
    Judith A Holloway
    School of Medicine, University of Southampton, Southampton, UK
    Pediatr Allergy Immunol 20:119-25. 2009
    ..Thus, immaturity of cord blood DCs is likely to arise as a consequence of decreased ability to take up antigen (at least via IgG-mediated mechanisms) and reduced provision of co-stimulation...
  6. ncbi request reprint The effect of labor on neonatal T-cell phenotype and function
    Catherine A Thornton
    Infection, Inflammation and Repair, School of Medicine, University of Southampton, UK
    Pediatr Res 54:120-4. 2003
    ....
  7. doi request reprint Thymic stromal lymphopoietin is present in human breast milk
    Trisha V Macfarlane
    Institute of Life Science, School of Medicine, Swansea University, Swansea, UK
    Pediatr Allergy Immunol 21:e454-6. 2010
    ..001) at 3-5 days than at 11-26 days postpartum. The potential role of breast milk TSLP in the development of immune function within the neonatal gastrointestinal tract and the development of allergy in childhood remain to be determined...
  8. doi request reprint Analysis of quantum dot fluorescence stability in primary blood mononuclear cells
    Huw D Summers
    Multidisciplinary Nanotechnology Center, School of Engineering, Swansea University, Swansea SA28PP, United Kingdom
    Cytometry A 77:933-9. 2010
    ..These results provide phenomenological descriptions of the evolving QD fluorescence within live cells with associated analytical equations that allow quantitative assessment of QD-based assays...
  9. ncbi request reprint Expression of CD21 and CD23 during human fetal development
    Catherine A Thornton
    Allergy and Inflammation Sciences, School of Medicine, University of Southampton, SO16 6YD, UK
    Pediatr Res 52:245-50. 2002
    ..However the abundance of CD21-positive T cells could alter the T- and B-cell interaction necessary for IgE switching by B cells and, thereby, especially with impaired IL-4 production, limit IgE production...
  10. doi request reprint Dietary supplementation with lactobacilli and bifidobacteria is well tolerated and not associated with adverse events during late pregnancy and early infancy
    Stephen J Allen
    The School of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP, Wales, UK
    J Nutr 140:483-8. 2010
    ..None of the AE were attributed to the intervention. Our findings support the safe use of this consortium of organisms during pregnancy and early infancy...
  11. ncbi request reprint Functional maturation of CD4+CD25+CTLA4+CD45RA+ T regulatory cells in human neonatal T cell responses to environmental antigens/allergens
    Catherine A Thornton
    School of Medicine, University of Wales, Swansea, United Kingdom
    J Immunol 173:3084-92. 2004
    ....
  12. doi request reprint The impact of cell culture equipment on energy loss
    Lleucu B Davies
    Institute of Life Science, College of Medicine, Swansea University, Swansea, Wales, UK
    Lasers Med Sci 29:195-202. 2014
    ..Phenol red-free media are the media of choice; polystyrene vessels with flat surfaces such as culture flasks or multi-well plates should be used in preference to polypropylene or glass vessels. ..
  13. pmc Volunteer bias in recruitment, retention, and blood sample donation in a randomised controlled trial involving mothers and their children at six months and two years: a longitudinal analysis
    Sue Jordan
    Department of Nursing, The College of Human and Health Sciences, Swansea University, Singleton Park, Swansea, Wales, United Kingdom
    PLoS ONE 8:e67912. 2013
    ..The vulnerability of clinical trials to volunteer bias is under-reported. Volunteer bias is systematic error due to differences between those who choose to participate in studies and those who do not...
  14. pmc Protocol of the baseline assessment for the Environments for Healthy Living (EHL) Wales cohort study
    Rebecca A Hill
    School of Medicine, Swansea University, Singleton Park, Swansea, UK
    BMC Public Health 10:150. 2010
    ..The baseline assessment will focus on birth outcomes and maternal and infant health...
  15. ncbi request reprint Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk
    Emmanuel LeBouder
    Infection and Immunity, Department of Medical Biochemistry and Immunology, Cardiff University College of Medicine, Heath Park, Cardiff CF14 4XX, Wales, UK
    J Immunol 176:3742-52. 2006
    ..This in turn suggests the existence of novel mechanisms regulating TLR activation...