P A Thomson

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi request reprint Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor
    P A Thomson
    Medical Genetics Section, University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh EH4 2XU, Scotland
    Mol Psychiatry 10:470-8. 2005
  2. ncbi request reprint Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
    P A Thomson
    Medical Genetics Section, University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh, UK
    Mol Psychiatry 10:657-68, 616. 2005
  3. ncbi request reprint Association between genotype at an exonic SNP in DISC1 and normal cognitive aging
    P A Thomson
    Medical Genetics Section, Department of Medical Sciences, University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh EH4 2XU, UK
    Neurosci Lett 389:41-5. 2005
  4. ncbi request reprint Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population
    P A Thomson
    Department of Medical Sciences, Medical Genetics Section, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Mol Psychiatry 12:94-104. 2007
  5. ncbi request reprint Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia
    A Christoforou
    Medical Genetics Section, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Mol Psychiatry 12:1011-25. 2007
  6. doi request reprint Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder
    B S Pickard
    Department of Medical Genetics, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Mol Psychiatry 14:874-84. 2009
  7. ncbi request reprint Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia
    S L Underwood
    Medical Genetics Section, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Mol Psychiatry 11:384-94. 2006
  8. ncbi request reprint Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder
    B S Pickard
    Medical Genetics Section, School of Clinical and Molecular Medicine, Molecular Medicine Centre, University of Edinburgh, Edinburgh, UK
    Mol Psychiatry 11:847-57. 2006
  9. ncbi request reprint Genetics of schizophrenia and bipolar affective disorder: strategies to identify candidate genes
    D J Porteous
    Medical Genetics Section, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, EH4 2XU
    Cold Spring Harb Symp Quant Biol 68:383-94. 2003

Detail Information

Publications9

  1. ncbi request reprint Sex-specific association between bipolar affective disorder in women and GPR50, an X-linked orphan G protein-coupled receptor
    P A Thomson
    Medical Genetics Section, University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh EH4 2XU, Scotland
    Mol Psychiatry 10:470-8. 2005
    ....
  2. ncbi request reprint Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population
    P A Thomson
    Medical Genetics Section, University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh, UK
    Mol Psychiatry 10:657-68, 616. 2005
    ..This result provides further supporting evidence for DISC1 as a susceptibility factor for both bipolar disorder and schizophrenia, consistent with the diagnoses in the original Scottish translocation family...
  3. ncbi request reprint Association between genotype at an exonic SNP in DISC1 and normal cognitive aging
    P A Thomson
    Medical Genetics Section, Department of Medical Sciences, University of Edinburgh, Molecular Medicine Centre, Western General Hospital, Edinburgh EH4 2XU, UK
    Neurosci Lett 389:41-5. 2005
    ..034 and 0.043, respectively). Women homozygous for the Cys allele had significantly lower cognitive ability scores than men at age 79, p = 0.003. Variation in DISC1 may therefore affect cognitive aging especially in women...
  4. ncbi request reprint Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population
    P A Thomson
    Department of Medical Sciences, Medical Genetics Section, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Mol Psychiatry 12:94-104. 2007
    ..Our study identifies a new of NRG1 region involved in schizophrenia and bipolar disorder in the Scottish population...
  5. ncbi request reprint Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia
    A Christoforou
    Medical Genetics Section, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Mol Psychiatry 12:1011-25. 2007
    ..This study has identified significant associations between BP and SCZ within the chromosome 4p linkage region, resulting in candidate regions worthy of further investigation...
  6. doi request reprint Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder
    B S Pickard
    Department of Medical Genetics, Molecular Medicine Centre, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Mol Psychiatry 14:874-84. 2009
    ....
  7. ncbi request reprint Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia
    S L Underwood
    Medical Genetics Section, Molecular Medicine Centre, Western General Hospital, University of Edinburgh, Edinburgh, UK
    Mol Psychiatry 11:384-94. 2006
    ..038 and 0.032) and in the full sample of affected female individuals (P=0.044 and 0.033). Our results provide preliminary evidence for the involvement of GPR78 in susceptibility to BPAD and SCZ in the Scottish population...
  8. ncbi request reprint Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder
    B S Pickard
    Medical Genetics Section, School of Clinical and Molecular Medicine, Molecular Medicine Centre, University of Edinburgh, Edinburgh, UK
    Mol Psychiatry 11:847-57. 2006
    ..We propose that these convergent cytogenetic and genetic findings provide molecular evidence for common aetiologies for different psychiatric conditions and further support the 'glutamate hypothesis' of psychotic illness...
  9. ncbi request reprint Genetics of schizophrenia and bipolar affective disorder: strategies to identify candidate genes
    D J Porteous
    Medical Genetics Section, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, EH4 2XU
    Cold Spring Harb Symp Quant Biol 68:383-94. 2003