Research Topics
Species | Jennifer C ThompsonSummaryAffiliation: University of Manchester Country: UK Publications
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Detail Information
Publications
Behavior in Huntington's disease: dissociating cognition-based and mood-based changesJennifer C Thompson
Cerebral Function Unit, Greater Manchester Neuroscience Center, Salford, United Kingdom
J Neuropsychiatry Clin Neurosci 14:37-43. 2002..The findings suggest that certain behavioral alterations are intrinsic to the evolution and progression of HD, whereas others are more variable and are independent of other indices of disease progression...
New learning and remote memory in atypical Alzheimer's diseaseJennifer C Thompson
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Hope Hospital, Manchester, Salford, UK
Cortex 39:751-66. 2003..e. 'old' versus 'recent') are considered, with particular reference to the contrasting theoretical frameworks that have recently been advanced by Squire and Moscovitch...
Variability in cognitive presentation of Alzheimer's diseaseCheryl L Stopford
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal Hospital NHS Foundation Trust, Salford, UK
Cortex 44:185-95. 2008..The findings emphasise variability in presentation and indicate that distinct phenotypic variations appear to lie on a continuum rather than representing discrete forms of disease...
Working memory, attention, and executive function in Alzheimer's disease and frontotemporal dementiaCheryl L Stopford
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, UK
Cortex 48:429-46. 2012..They underline also the phenotypic variation within AD...
Longitudinal evaluation of neuropsychiatric symptoms in Huntington's diseaseJennifer C Thompson
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, Salford, UK
J Neuropsychiatry Clin Neurosci 24:53-60. 2012..Depression did not increase significantly at any stage of disease. The neuropsychiatric syndrome of apathy appears to be intrinsic to the evolution and progression of HD...
Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutationsJulie S Snowden
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal Foundation Trust, Salford, M6 8HD, UK
Brain 135:693-708. 2012..Mutations in the C9ORF72 gene may be a major cause not only of frontotemporal dementia with motor neuron disease but also of late onset psychosis...
Famous people knowledge and the right and left temporal lobesJulie S Snowden
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal Foundation Trust, Salford, UK
Behav Neurol 25:35-44. 2012..The data present a challenge for the influential `semantic hub' model, which views the anterior temporal lobes as an area of convergence in which semantic information is represented in amodal form...
The clinical diagnosis of early-onset dementias: diagnostic accuracy and clinicopathological relationshipsJulie S Snowden
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
Brain 134:2478-92. 2011..Moreover, careful clinical phenotyping allows prediction of histopathological subtype of frontotemporal lobar degeneration. The principles guiding diagnosis provide the foundation for future prospective studies...
Distinct memory profiles in Alzheimer's diseaseCheryl L Stopford
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Hope Hospital, Salford, UK
Cortex 43:846-57. 2007..The link between working memory and language performance, together with findings of posterior hemisphere abnormalities on neuroimaging, lead us to reassess the nature of working memory deficits in AD...
Progressive aphasia presenting with deep dyslexia and dysgraphiaJulie S Snowden
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal Foundation Trust, Salford, UK
Cortex 48:1234-9. 2012..TheĀ findings have potential practical implications for speech and language therapy in progressive aphasia. Moreover, they illustrate both the remarkable specificity yet clinical diversity in presentation of progressive aphasia...
Automaticity and attention in Huntington's disease: when two hands are not better than oneJennifer C Thompson
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, M6 8HD, UK
Neuropsychologia 48:171-8. 2010..The findings have implications for the interpretation of 'high level' deficits in attention and executive function previously reported in HD...
Frontotemporal dementia with amyotrophic lateral sclerosis: A clinical comparison of patients with and without repeat expansions in C9orf72Julie S Snowden
Manchester Academic Health Sciences Centre, Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal NHS Foundation Trust, Salford
Amyotroph Lateral Scler Frontotemporal Degener 14:172-6. 2013..The presence of psychiatric symptoms in the context of FTD-ALS should alert clinicians to the possibility of C9orf72 expansions...
Cognitive phenotypes in Alzheimer's disease and genetic variants in ACE and IDEEmma R L C Vardy
Cerebral Function Unit, Salford Royal NHS Foundation Trust, Salford, UK
Neurobiol Aging 33:1486.e1-2. 2012..Of the 10 genetic variants of IDE, and the 3 genetic variants of ACE studied, only ACErs4291 and ACErs1800764 were nominally associated with the amnestic presentation...
Understanding quantity in semantic dementiaCamille L Julien
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal Foundation Trust, Salford, UK
Cogn Neuropsychol 27:3-29. 2010..The findings challenge the view that knowledge of quantity is totally preserved in SD and suggest that the temporal lobes have a contributory role in the conceptual understanding of quantity...
Cognitive phenotypes in Alzheimer's disease and genetic riskJulie S Snowden
Clinical Neuroscience Research Group, Greater Manchester Neuroscience Centre, Hope Hospital, Salford, UK
Cortex 43:835-45. 2007..The findings indicate that risk factors other than APOE epsilon4 allele underlie the non-familial, early onset posterior hemisphere presentations of AD...
Psychiatric disorders in preclinical Huntington's diseaseCamille L Julien
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Hope Hospital, Salford, UK
J Neurol Neurosurg Psychiatry 78:939-43. 2007..Few studies have investigated the temporal course of psychiatric disorder across the preclinical period...
The relationship between alcohol use and risk-taking sexual behaviors in a large behavioral studyJennifer C Thompson
Division of Epidemiology and Biostatistics, Department of Preventive Medicine and Biometrics (PMB, Uniformed Services University of the Health Sciences (USUHS, 4301 Jones Bridge Road, Bethesda, MD 20814-4799, USA
Prev Med 41:247-52. 2005..However, the results are compatible with a personality-based hypothesis, in which individuals with certain sensation-seeking tendencies may incur an increased risk for sexually transmitted infections...
