Evropi Theodoratou

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi request reprint Estimating the incidence of colorectal cancer in South East Asia
    Inka Kokki
    Evropi Theodoratou, Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Croat Med J 54:532-40. 2013
  2. pmc Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e37662. 2012
  3. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
  4. pmc Estimating pneumonia deaths of post-neonatal children in countries of low or no death certification in 2008
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, United Kingdom
    PLoS ONE 6:e25095. 2011
  5. doi request reprint Association between common mtDNA variants and all-cause or colorectal cancer mortality
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Carcinogenesis 31:296-301. 2010
  6. doi request reprint Dietary vitamin B6 intake and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 17:171-82. 2008
  7. pmc Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e63475. 2013
  8. pmc Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis
    Albert Tenesa
    Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, University of Edinburgh and MRC Human Genetics Unit, Edinburgh, United Kingdom
    Clin Cancer Res 16:3754-9. 2010
  9. doi request reprint Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, United Kingdom
    Int J Cancer 123:2170-9. 2008
  10. pmc The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e38123. 2012

Detail Information

Publications34

  1. ncbi request reprint Estimating the incidence of colorectal cancer in South East Asia
    Inka Kokki
    Evropi Theodoratou, Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Croat Med J 54:532-40. 2013
    ..To estimate the burden of colorectal cancer (CRC) in South East Asia...
  2. pmc Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e37662. 2012
    ..To elucidate the effect of vitamin D on CRC cancer risk, additional large studies of vitamin D and CRC risk are required and/or the application of alternative methods that are less sensitive to weak instrument restrictions...
  3. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
    ..Currently there are at least seven vaccine and immunotherapy candidates against S. aureus in the developmental phase targeting both active and passive immunization...
  4. pmc Estimating pneumonia deaths of post-neonatal children in countries of low or no death certification in 2008
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, United Kingdom
    PLoS ONE 6:e25095. 2011
    ....
  5. doi request reprint Association between common mtDNA variants and all-cause or colorectal cancer mortality
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Carcinogenesis 31:296-301. 2010
    ..These findings are interesting and consistent with other biological knowledge but need to be confirmed through replication in independent cohorts...
  6. doi request reprint Dietary vitamin B6 intake and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 17:171-82. 2008
    ..Evidence from larger cohort and experimental studies is now required to confirm and define the anticarcinogenic actions of vitamin B6 and to explore the mechanisms by which this effect is mediated...
  7. pmc Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e63475. 2013
    ..We investigate the direction of causation between vitamin D and CRC by extending the conventional approaches to allow pleiotropic relationships and by explicitly modelling unmeasured confounders...
  8. pmc Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis
    Albert Tenesa
    Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, University of Edinburgh and MRC Human Genetics Unit, Edinburgh, United Kingdom
    Clin Cancer Res 16:3754-9. 2010
    ..To date, genomewide association studies have identified 10 genetic loci associated with colorectal cancer (CRC) susceptibility. We hypothesized that these loci might also affect cancer survival...
  9. doi request reprint Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, United Kingdom
    Int J Cancer 123:2170-9. 2008
    ..70, 95% CI 0.56, 0.87). The evidence of interaction we report here further supports the inverse association between vitamin D mediated through binding to the VDR...
  10. pmc The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e38123. 2012
    ..Objective of this study was to investigate the association between plasma urate concentration and: a) food items: dairy, sugar-sweetened beverages (SSB) and purine-rich vegetables; b) related nutrients: lactose, calcium and fructose...
  11. doi request reprint Modification of the associations between lifestyle, dietary factors and colorectal cancer risk by APC variants
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    Carcinogenesis 29:1774-80. 2008
    ..However, further large-scale studies are necessary in order to replicate these findings and confirm the role of these APC gene variants and their interaction with dietary and lifestyle exposures in colorectal carcinogenesis...
  12. pmc Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage
    Fatim Lakha
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK
    BMC Cancer 12:487. 2012
    ..Epidemiological studies have reported conflicting associations between statins and CRC risk and there is one published report of the association between statins and CRC survival...
  13. ncbi request reprint Dietary fatty acids and colorectal cancer: a case-control study
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Am J Epidemiol 166:181-95. 2007
    ..The observed different effects of different types of fatty acids underline the importance of type of fat in the etiology and prevention of colorectal cancer...
  14. pmc Diet, environmental factors, and lifestyle underlie the high prevalence of vitamin D deficiency in healthy adults in Scotland, and supplementation reduces the proportion that are severely deficient
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    J Nutr 141:1535-42. 2011
    ....
  15. pmc The effect of Haemophilus influenzae type b and pneumococcal conjugate vaccines on childhood pneumonia incidence, severe morbidity and mortality
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i172-85. 2010
    ....
  16. doi request reprint Associations between dietary and lifestyle risk factors and colorectal cancer in the Scottish population
    Evropi Theodoratou
    aDepartment of Environmental and Occupational Medicine, Liberty Safe Work Research Centre, University of Aberdeen, Aberdeen bCentre for Population Health Sciences, College of Medicine and Veterinary Medicine cColon Cancer Genetics Group, Institute of Genetics and Molecular Medicine dSchool of Informatics, College of Science and Engineering, University of Edinburgh eSchool of Nursing, Midwifery and Social Care, Faculty of Health, Life and Social Sciences, Edinburgh Napier University fSouth East Scotland Genetic Service, Western General Hospital, Edinburgh, UK
    Eur J Cancer Prev 23:8-17. 2014
    ....
  17. pmc An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S30. 2011
    ..Currently there are several vaccine and immunoprophylaxis candidates against RSV in the developmental phase targeting active and passive immunization...
  18. pmc An evaluation of respiratory administration of measles vaccine for prevention of acute lower respiratory infections in children
    Daisy Higginson
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S31. 2011
    ..Aerosolised measles vaccines are now under development with the hope of challenging the delivery factors currently limiting the coverage of the existing vaccine...
  19. pmc Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries
    Igor Rudan
    Centre for Population Health Sciences and Global Health Academy, University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 3:10401. 2013
    ..This should allow national policy-makers and stakeholders to implement proposed policies in the World Health Organization (WHO) and UNICEF member countries...
  20. pmc An evaluation of oxygen systems for treatment of childhood pneumonia
    Alastair G Catto
    Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, UK
    BMC Public Health 11:S28. 2011
    ..This review aims to assess the utility of oxygen systems as a method for reducing childhood mortality from pneumonia...
  21. ncbi request reprint Dietary flavonoids and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 16:684-93. 2007
    ..22), and phytoestrogens (P(trend) = 0.26). This was the first of several a priori hypotheses to be tested in this large study and showed strong and linear inverse associations of flavonoids with colorectal cancer risk...
  22. pmc Abundant pleiotropy in human complex diseases and traits
    Shanya Sivakumaran
    Centre for Population Health Sciences, The University of Edinburgh, Edinburgh EH8 9AG, UK
    Am J Hum Genet 89:607-18. 2011
    ....
  23. pmc An evaluation of emerging vaccines for childhood meningococcal disease
    Debajeet Choudhuri
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S29. 2011
    ..We aimed to perform a structured assessment of these emerging meningococcal vaccines as a means of reducing global meningococcal disease burden among children under 5 years of age...
  24. pmc An evaluation of emerging vaccines for childhood pneumococcal pneumonia
    Julia Webster
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S26. 2011
    ....
  25. pmc The effect of case management on childhood pneumonia mortality in developing countries
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i155-71. 2010
    ....
  26. doi request reprint Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 378:1917-30. 2011
    ..We aimed to estimate the global incidence of and mortality from lower respiratory infections associated with influenza in children younger than 5 years...
  27. doi request reprint Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, UK
    J Natl Cancer Inst 104:1433-57. 2012
    ..chs.med.ed.ac.uk/CRCgene/)...
  28. doi request reprint Causes of deaths in children younger than 5 years in China in 2008
    Igor Rudan
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Lancet 375:1083-9. 2010
    ..We identified the main causes of deaths in neonates (<1 month), postneonatal infants (1-11 months), and children (<5 years) in China using information that was available to the public...
  29. pmc Setting research priorities to reduce global mortality from childhood pneumonia by 2015
    Igor Rudan
    Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, Scotland, United Kingdom
    PLoS Med 8:e1001099. 2011
    ..Igor Rudan and colleagues report the results of their consensus building exercise that identified health research priorities to help reduce child mortality from pneumonia...
  30. pmc Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality: An application of Equitable Impact Sensitive Tool (EQUIST) in five low- and middle-income countries
    Donald Waters
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20402. 2012
    ....
  31. doi request reprint Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
    Malcolm G Dunlop
    Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council MRC Human Genetics Unit, Edinburgh, UK
    Nat Genet 44:770-6. 2012
    ..2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC...
  32. pmc Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 375:1545-55. 2010
    ..We aimed to estimate the global incidence of and mortality from episodes of acute lower respiratory infection (ALRI) due to RSV in children younger than 5 years in 2005...
  33. doi request reprint Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    BMJ 348:g2035. 2014
    ..To evaluate the breadth, validity, and presence of biases of the associations of vitamin D with diverse outcomes...
  34. pmc Estimating the incidence of colorectal cancer in Sub-Saharan Africa: A systematic analysis
    Alice Graham
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20404. 2012
    ..This study analyses the data available to produce an estimate of the incidence of colorectal cancer in Sub-Saharan Africa (SSA)...