Evropi Theodoratou

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. ncbi Dietary flavonoids and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 16:684-93. 2007
  2. doi Dietary vitamin B6 intake and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 17:171-82. 2008
  3. ncbi Modification of the associations between lifestyle, dietary factors and colorectal cancer risk by APC variants
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    Carcinogenesis 29:1774-80. 2008
  4. pmc Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria
    Mohammad Yawar Yakoob
    Division of Women and Child Health, The Aga Khan University, Karachi, Pakistan
    BMC Public Health 11:S23. 2011
  5. ncbi Associations between dietary and lifestyle risk factors and colorectal cancer in the Scottish population
    Evropi Theodoratou
    aDepartment of Environmental and Occupational Medicine, Liberty Safe Work Research Centre, University of Aberdeen, Aberdeen bCentre for Population Health Sciences, College of Medicine and Veterinary Medicine cColon Cancer Genetics Group, Institute of Genetics and Molecular Medicine dSchool of Informatics, College of Science and Engineering, University of Edinburgh eSchool of Nursing, Midwifery and Social Care, Faculty of Health, Life and Social Sciences, Edinburgh Napier University fSouth East Scotland Genetic Service, Western General Hospital, Edinburgh, UK
    Eur J Cancer Prev 23:8-17. 2014
  6. pmc Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e63475. 2013
  7. pmc Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis
    Albert Tenesa
    Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, University of Edinburgh and MRC Human Genetics Unit, Edinburgh, United Kingdom
    Clin Cancer Res 16:3754-9. 2010
  8. pmc The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e38123. 2012
  9. ncbi Association between common mtDNA variants and all-cause or colorectal cancer mortality
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Carcinogenesis 31:296-301. 2010
  10. ncbi Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, United Kingdom
    Int J Cancer 123:2170-9. 2008

Detail Information

Publications27

  1. ncbi Dietary flavonoids and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 16:684-93. 2007
    ..22), and phytoestrogens (P(trend) = 0.26). This was the first of several a priori hypotheses to be tested in this large study and showed strong and linear inverse associations of flavonoids with colorectal cancer risk...
  2. doi Dietary vitamin B6 intake and the risk of colorectal cancer
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Vet Medicine, University of Edinburgh, Edinburgh, United Kingdom
    Cancer Epidemiol Biomarkers Prev 17:171-82. 2008
    ..Evidence from larger cohort and experimental studies is now required to confirm and define the anticarcinogenic actions of vitamin B6 and to explore the mechanisms by which this effect is mediated...
  3. ncbi Modification of the associations between lifestyle, dietary factors and colorectal cancer risk by APC variants
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    Carcinogenesis 29:1774-80. 2008
    ..However, further large-scale studies are necessary in order to replicate these findings and confirm the role of these APC gene variants and their interaction with dietary and lifestyle exposures in colorectal carcinogenesis...
  4. pmc Preventive zinc supplementation in developing countries: impact on mortality and morbidity due to diarrhea, pneumonia and malaria
    Mohammad Yawar Yakoob
    Division of Women and Child Health, The Aga Khan University, Karachi, Pakistan
    BMC Public Health 11:S23. 2011
    ....
  5. ncbi Associations between dietary and lifestyle risk factors and colorectal cancer in the Scottish population
    Evropi Theodoratou
    aDepartment of Environmental and Occupational Medicine, Liberty Safe Work Research Centre, University of Aberdeen, Aberdeen bCentre for Population Health Sciences, College of Medicine and Veterinary Medicine cColon Cancer Genetics Group, Institute of Genetics and Molecular Medicine dSchool of Informatics, College of Science and Engineering, University of Edinburgh eSchool of Nursing, Midwifery and Social Care, Faculty of Health, Life and Social Sciences, Edinburgh Napier University fSouth East Scotland Genetic Service, Western General Hospital, Edinburgh, UK
    Eur J Cancer Prev 23:8-17. 2014
    ....
  6. pmc Model selection approach suggests causal association between 25-hydroxyvitamin D and colorectal cancer
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e63475. 2013
    ..We investigate the direction of causation between vitamin D and CRC by extending the conventional approaches to allow pleiotropic relationships and by explicitly modelling unmeasured confounders...
  7. pmc Ten common genetic variants associated with colorectal cancer risk are not associated with survival after diagnosis
    Albert Tenesa
    Colon Cancer Genetics Group and Academic Coloproctology, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, University of Edinburgh and MRC Human Genetics Unit, Edinburgh, United Kingdom
    Clin Cancer Res 16:3754-9. 2010
    ..To date, genomewide association studies have identified 10 genetic loci associated with colorectal cancer (CRC) susceptibility. We hypothesized that these loci might also affect cancer survival...
  8. pmc The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e38123. 2012
    ..Objective of this study was to investigate the association between plasma urate concentration and: a) food items: dairy, sugar-sweetened beverages (SSB) and purine-rich vegetables; b) related nutrients: lactose, calcium and fructose...
  9. ncbi Association between common mtDNA variants and all-cause or colorectal cancer mortality
    Evropi Theodoratou
    Public Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Carcinogenesis 31:296-301. 2010
    ..These findings are interesting and consistent with other biological knowledge but need to be confirmed through replication in independent cohorts...
  10. ncbi Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, United Kingdom
    Int J Cancer 123:2170-9. 2008
    ..70, 95% CI 0.56, 0.87). The evidence of interaction we report here further supports the inverse association between vitamin D mediated through binding to the VDR...
  11. pmc Statin use and association with colorectal cancer survival and risk: case control study with prescription data linkage
    Fatim Lakha
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK
    BMC Cancer 12:487. 2012
    ..Epidemiological studies have reported conflicting associations between statins and CRC risk and there is one published report of the association between statins and CRC survival...
  12. pmc Instrumental variable estimation of the causal effect of plasma 25-hydroxy-vitamin D on colorectal cancer risk: a mendelian randomization analysis
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 7:e37662. 2012
    ..To elucidate the effect of vitamin D on CRC cancer risk, additional large studies of vitamin D and CRC risk are required and/or the application of alternative methods that are less sensitive to weak instrument restrictions...
  13. ncbi Dietary fatty acids and colorectal cancer: a case-control study
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, United Kingdom
    Am J Epidemiol 166:181-95. 2007
    ..The observed different effects of different types of fatty acids underline the importance of type of fat in the etiology and prevention of colorectal cancer...
  14. pmc Diet, environmental factors, and lifestyle underlie the high prevalence of vitamin D deficiency in healthy adults in Scotland, and supplementation reduces the proportion that are severely deficient
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    J Nutr 141:1535-42. 2011
    ....
  15. pmc Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries
    Igor Rudan
    Centre for Population Health Sciences and Global Health Academy, University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 3:10401. 2013
    ..This should allow national policy-makers and stakeholders to implement proposed policies in the World Health Organization (WHO) and UNICEF member countries...
  16. pmc Abundant pleiotropy in human complex diseases and traits
    Shanya Sivakumaran
    Centre for Population Health Sciences, The University of Edinburgh, Edinburgh EH8 9AG, UK
    Am J Hum Genet 89:607-18. 2011
    ....
  17. pmc Estimating pneumonia deaths of post-neonatal children in countries of low or no death certification in 2008
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, United Kingdom
    PLoS ONE 6:e25095. 2011
    ....
  18. pmc Estimating the incidence of colorectal cancer in South East Asia
    Inka Kokki
    Evropi Theodoratou, Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
    Croat Med J 54:532-40. 2013
    ..To estimate the burden of colorectal cancer (CRC) in South East Asia...
  19. doi Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, UK
    J Natl Cancer Inst 104:1433-57. 2012
    ..chs.med.ed.ac.uk/CRCgene/)...
  20. pmc Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials
    Evropi Theodoratou
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh EH8 9AG, UK
    BMJ 348:g2035. 2014
    ..To evaluate the breadth, validity, and presence of biases of the associations of vitamin D with diverse outcomes...
  21. pmc Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality: An application of Equitable Impact Sensitive Tool (EQUIST) in five low- and middle-income countries
    Donald Waters
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20402. 2012
    ....
  22. ncbi Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
    Malcolm G Dunlop
    Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council MRC Human Genetics Unit, Edinburgh, UK
    Nat Genet 44:770-6. 2012
    ..2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC...
  23. pmc Setting research priorities to reduce global mortality from childhood pneumonia by 2015
    Igor Rudan
    Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, Scotland, United Kingdom
    PLoS Med 8:e1001099. 2011
    ..Igor Rudan and colleagues report the results of their consensus building exercise that identified health research priorities to help reduce child mortality from pneumonia...
  24. pmc An evaluation of oxygen systems for treatment of childhood pneumonia
    Alastair G Catto
    Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, UK
    BMC Public Health 11:S28. 2011
    ..This review aims to assess the utility of oxygen systems as a method for reducing childhood mortality from pneumonia...
  25. doi Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 378:1917-30. 2011
    ..We aimed to estimate the global incidence of and mortality from lower respiratory infections associated with influenza in children younger than 5 years...
  26. pmc The effect of Haemophilus influenzae type b and pneumococcal conjugate vaccines on childhood pneumonia incidence, severe morbidity and mortality
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i172-85. 2010
    ....
  27. pmc Estimating the incidence of colorectal cancer in Sub-Saharan Africa: A systematic analysis
    Alice Graham
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20404. 2012
    ..This study analyses the data available to produce an estimate of the incidence of colorectal cancer in Sub-Saharan Africa (SSA)...