Affiliation: University College London
- Post-mortem cerebral magnetic resonance imaging T1 and T2 in fetuses, newborns and infantsSudhin Thayyil
UCL Institute for Women s Health, 86 96 Chenies Mews, London, United Kingdom
Eur J Radiol 81:e232-8. 2012....
- Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4 T with conventional MRI and invasive autopsySudhin Thayyil
Centre for Cardiovascular Imaging, University College London UCL Institute of Child Health and Great Ormond Street Hospital for Children, London, UK
Lancet 374:467-75. 2009..High-field whole-body MRI at 9.4 T provides good images of small animals. We therefore compared the diagnostic usefulness of high-field MRI with conventional MRI for post-mortem examination of human fetuses...
- Can early-onset nonoliguric hyperkalemia be predicted in extremely premature infants?Sudhin Thayyil
Department of Cardiovascular Imaging, Great Ormond Street Hospital UCL Institute of Child Health, London, UK
Am J Perinatol 25:129-33. 2008..25; post-test probability, 4%). Mildly elevated potassium and phosphate levels within 6 hours after birth may be useful in predicting the development of early-onset hyperkalemia...
- A gestation- and postnatal age-based reference chart for assessing renal function in extremely premature infantsS Thayyil
Department of Cardiovascular Imaging, Great Ormond Street Hospital, UCL Institute of Child Health, London, UK
J Perinatol 28:226-9. 2008..The aim of this study was to create reference ranges for plasma creatinine in cohort of extremely premature infants...
- A semi-automated method for non-invasive internal organ weight estimation by post-mortem magnetic resonance imaging in fetuses, newborns and childrenSudhin Thayyil
Centre for Cardiovascular MR, Great Ormond Street Hospital for Children, UCL Institute of Child Health, University College London, 30 Guilford Street, London, UK
Eur J Radiol 72:321-6. 2009..Magnetic resonance (MR) imaging allows minimally invasive autopsy, especially when consent is declined for traditional autopsy. Estimation of individual visceral organ weights is an important component of traditional autopsy...
- Prospective parental consent for autopsy research following sudden unexpected childhood deaths: a successful modelS Thayyil
UCL Institute of Child Health, London, UK
Arch Dis Child 94:354-8. 2009..Organ retention issues, recent changes in the Coroners' (Amendment) Rules 2005 and the Human Tissue Act have resulted in pessimism regarding prospective consent for paediatric autopsy research in the UK...
- Therapeutic hypothermia for neonatal encephalopathy implications for neonatal units in IndiaSudhil Thayyil
UCL Institute of Child Health, London, UK
Indian Pediatr 46:283-9. 2009..The current practice of maintaining normothermia should continue, until such evidence is available...
- Less invasive autopsy: an evidenced based approachSudhin Thayyil
UCL Institute for Women s Health, University College London, 86 96 Chenies Mews, London, UK
Arch Dis Child 96:681-7. 2011..A joint effort between clinicians, radiologists, pathologists, parent groups and funding bodies is essential for the successful implementation of less invasive autopsy in the UK...
- Normal ascent of the conus medullaris: a post-mortem foetal MRI studyO J Arthurs
Great Ormond Street Hospital for Children, London, WC1N 3JH, UK
J Matern Fetal Neonatal Med 26:697-702. 2013..We used magnetic resonance imaging (MRI) to measure the position of the conus in post-mortem foetuses, to investigate the timing of normal ascent...
- High quality genomic DNA extraction from postmortem fetal tissueS Addison
Academic Neonatology, Institute for Women s Health, University College London, London, UK
J Matern Fetal Neonatal Med 25:2467-9. 2012..We examined the yield and quality of genomic deoxyribonucleic acid (DNA) extracted from various postmortem fetal tissues...
- Acceptability of a minimally invasive perinatal/paediatric autopsy: healthcare professionals' views and implications for practiceK Ben-Sasi
Department of Paediatric Pathology, Great Ormond Street Hospital, London, UK
Prenat Diagn 33:307-12. 2013..Technology now enables less invasive alternatives to traditional autopsy and may increase the acceptability of post-mortem examination...
- Minimally invasive fetal postmortem examination using magnetic resonance imaging and computerised tomography: current evidence and practical issuesS Thayyil
Department of Radiology, Institute of Child Health, University College London, London, UK
Prenat Diagn 30:713-8. 2010..Here, we review the case for the development of less invasive autopsy using combined investigations including imaging techniques, in particular, magnetic resonance imaging and computerised tomography...
- Diagnostic accuracy of post-mortem magnetic resonance imaging in fetuses, children and adults: a systematic reviewSudhin Thayyil
Centre for Cardiovascular Imaging, UCL Institute of Child Health, London, UK
Eur J Radiol 75:e142-8. 2010..Well designed, large, prospective studies are required to evaluate the accuracy of post-mortem MR imaging, before it can be offered as a clinical tool...
- Techniques for therapeutic hypothermia during transport and in hospital for perinatal asphyxial encephalopathyNicola J Robertson
Neonatology, Institute for Women s Health, University College London, 86 96 Chenies Mews, London WC1E 6HX, UK
Semin Fetal Neonatal Med 15:276-86. 2010..We describe our experience of passive cooling before and during the transfer of infants with encephalopathy to cooling centres in a major city in the UK...
- Cerebral magnetic resonance biomarkers in neonatal encephalopathy: a meta-analysisSudhin Thayyil
MBBS, MRCPCH, UCL Institute for Women s Health, Department of Neonatology, 86 96 Chenies Mews, London WC1E 6HX, England
Pediatrics 125:e382-95. 2010..We undertook a meta-analysis of the prognostic accuracy of cerebral magnetic resonance (MR) biomarkers in infants with neonatal encephalopathy...
- Post-mortem MRI as an alternative to non-forensic autopsy in foetuses and children: from research into clinical practiceS Addison
Perinatal Neurology and Neonatology, Imperial College London, London, UK
Br J Radiol 87:20130621. 2014..In the short to medium term, it is desirable that a supraregional network of specialist centres should be established to provide this service within the current National Health Service framework. ..
- Optimal endotracheal tube tip position in extremely premature infantsSudhin Thayyil
Department of Cardiovascular Imaging, Great Ormond Street Hospital UCL Institute of Child Health, London
Am J Perinatol 25:13-6. 2008..We concluded that the ETT tip should be kept at the level of the first or second thoracic vertebrae in extremely premature babies to reduce the incidence of nonuniform lung aeration and adverse pulmonary outcomes...
- Is procalcitonin useful in early diagnosis of serious bacterial infections in children?Sudhin Thayyil
Department of Paediatrics and Chemical Pathology, University Hospital of North Tees and Hartlepool, UK
Acta Paediatr 94:155-8. 2005..To compare diagnostic accuracy of procalcitonin for early diagnosis of serious bacterial infection (SBI) in children presenting with fever and no focus of infection...