Nigel Temperton

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes
    Nigel J Temperton
    Wohl Virion Centre and Division of Infection and Immunity, University College London, 46 Cleveland St, London W1T 4JF, London, UK
    Emerg Infect Dis 11:411-6. 2005
  2. doi request reprint A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies
    Nigel J Temperton
    MRC UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London, United Kingdom
    Influenza Other Respi Viruses 1:105-12. 2007
  3. ncbi request reprint BirdFlu2009: Avian Influenza and Human Health. 9-10 September 2009, Oxford, UK
    Nigel Temperton
    University College London, Wohl Virion Centre, Division of Infection and Immunity, 46 Cleveland Street, London, W1T 4JF, UK
    IDrugs 12:686-8. 2009
  4. pmc Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison
    Edward Wright
    MRC UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, UK
    J Gen Virol 89:2204-13. 2008
  5. doi request reprint Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses
    Edward Wright
    Division of Infection and Immunity, University College London, 46 Cleveland Street, London, W1T 4JF, UK
    Virology 408:183-9. 2010
  6. ncbi request reprint Enhancement of humoral immune responses to a human cytomegalovirus DNA vaccine: adjuvant effects of aluminum phosphate and CpG oligodeoxynucleotides
    Nigel J Temperton
    Department of Virology, Royal Free and University College Medical School, London, United Kingdom
    J Med Virol 70:86-90. 2003
  7. pmc T cell responses to whole SARS coronavirus in humans
    Chris Ka fai Li
    MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK
    J Immunol 181:5490-500. 2008
  8. doi request reprint In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses
    Ching Yao Su
    Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Taipei 115, Taiwan
    Antiviral Res 79:199-205. 2008

Collaborators

Detail Information

Publications8

  1. pmc Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes
    Nigel J Temperton
    Wohl Virion Centre and Division of Infection and Immunity, University College London, 46 Cleveland St, London W1T 4JF, London, UK
    Emerg Infect Dis 11:411-6. 2005
    ..The pseudotype assay does not require handling live SARS virus; it is a useful tool to determine neutralizing titers during natural infection and the preclinical evaluation of candidate vaccines...
  2. doi request reprint A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies
    Nigel J Temperton
    MRC UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London, United Kingdom
    Influenza Other Respi Viruses 1:105-12. 2007
    ..We have used retroviral pseudotypes bearing influenza H5 hemagglutinin (HA) as safe, surrogate viruses for influenza neutralization assays which can be carried out at Biosafety Level 2...
  3. ncbi request reprint BirdFlu2009: Avian Influenza and Human Health. 9-10 September 2009, Oxford, UK
    Nigel Temperton
    University College London, Wohl Virion Centre, Division of Infection and Immunity, 46 Cleveland Street, London, W1T 4JF, UK
    IDrugs 12:686-8. 2009
    ..Investigational drugs discussed include NEX-DAS-181 (NexBio Inc) and MVA-NP-M1 (The Edward Jenner Institute for Vaccine Research)...
  4. pmc Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison
    Edward Wright
    MRC UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, UK
    J Gen Virol 89:2204-13. 2008
    ....
  5. doi request reprint Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses
    Edward Wright
    Division of Infection and Immunity, University College London, 46 Cleveland Street, London, W1T 4JF, UK
    Virology 408:183-9. 2010
    ..helvum remains high enough to persist in this species. This supports the hypothesis that LBV is endemic in Ghanaian E. helvum and we speculate that LBV may have co-evolved with African megachiroptera...
  6. ncbi request reprint Enhancement of humoral immune responses to a human cytomegalovirus DNA vaccine: adjuvant effects of aluminum phosphate and CpG oligodeoxynucleotides
    Nigel J Temperton
    Department of Virology, Royal Free and University College Medical School, London, United Kingdom
    J Med Virol 70:86-90. 2003
    ..The results provide a rationale for evaluating combinations of other HCMV proteins for incorporation into a multi-target DNA vaccine, and for the optimization of adjuvant usage, to elicit enhanced levels of neutralizing antibodies. 2003...
  7. pmc T cell responses to whole SARS coronavirus in humans
    Chris Ka fai Li
    MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK
    J Immunol 181:5490-500. 2008
    ..Our study provides a roadmap for the immunogenicity of SARS-CoV and types of immune responses that may be responsible for the virus clearance, and should serve as a benchmark for SARS-CoV vaccine design and evaluation...
  8. doi request reprint In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses
    Ching Yao Su
    Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Taipei 115, Taiwan
    Antiviral Res 79:199-205. 2008
    ....