Research Topics
Genomes and Genes | Maximilian J TelfordSummaryAffiliation: University College London Country: UK Publications
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Publications
Deuterostome phylogeny reveals monophyletic chordates and the new phylum XenoturbellidaSarah J Bourlat
Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Nature 444:85-8. 2006..As such, Xenoturbella is shown to be an independent phylum, Xenoturbellida, bringing the number of living deuterostome phyla to four...- A single origin of the central nervous system?Maximilian J Telford
Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Cell 129:237-9. 2007.... 
Animal evolution: once upon a timeMaximilian J Telford
Department of Genetics, Evolution and Environment, University College London, London, UK
Curr Biol 19:R339-41. 2009..The evolutionary relationships between the earliest branches of the animal kingdom - bilaterians, cnidarians, ctenophores, sponges and placozoans - are contentious. A new phylogenomic analysis suggests a return to old ideas...
Field et Al. ReduxMaximilian J Telford
Department of Genetics, Evolution and Environment University College London, Darwin Building Gower Street, London, WC1E 6BT, UK
Evodevo 4:5. 2013..This approach illustrates the basis of some of the major advances of the past 25 years resulting in our current understanding of animal phylogeny...- Comparative gene expression supports the origin of the incisor and molar process from a single endite in the mandible of the red flour beetle Tribolium castaneumJoshua F Coulcher
Department of Genetics, Environment and Evolution, University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK
Evodevo 4:1. 2013..abstract:.. - Cap'n'collar differentiates the mandible from the maxilla in the beetle Tribolium castaneumJoshua F Coulcher
Department of Genetics, Environment and Evolution, University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK
Evodevo 3:25. 2012..abstract:.. - Expression of homothorax and extradenticle mRNA in the legs of the crustacean Parhyale hawaiensis: evidence for a reversal of gene expression regulation in the pancrustacean lineageNikola Michael Prpic
Department of Developmental Biology, GZMB New Building, Georg August University Goettingen, Johann Friedrich Blumenbach Institute for Zoology and Anthropology, Justus von Liebig Weg 11, Goettingen, Germany
Dev Genes Evol 218:333-9. 2008..Our data suggest that the reversal of the gene expression regulation of hth and exd occurred in the pancrustacean lineage... - The mitochondrial genome structure of Xenoturbella bocki (phylum Xenoturbellida) is ancestral within the deuterostomesSarah J Bourlat
Department of Invertebrate Zoology, Swedish Museum of Natural History, Stockholm, Sweden
BMC Evol Biol 9:107. 2009..Here we present analyses comparing the Xenoturbella bocki mitochondrial gene order, genetic code and control region to those of other metazoan groups... - PhylogenomicsMaximilian J Telford
Department of Biology, University College London, London WC1E 6BT, UK
Curr Biol 17:R945-6. 2007 - The evolution of the EcdysozoaMaximilian J Telford
Department of Biology, University College London, London WC1E 6BT, UK
Philos Trans R Soc Lond B Biol Sci 363:1529-37. 2008..Relationships within Ecdysozoa are also controversial and we discuss the molecular and morphological evidence for a number of monophyletic groups within this superphylum... - The evolution of the animals: introduction to a Linnean tercentenary celebrationMaximilian J Telford
Department of Biology, University College London, London WC1E 6BT, UK
Philos Trans R Soc Lond B Biol Sci 363:1421-4. 2008.... - Resolving animal phylogeny: a sledgehammer for a tough nut?Maximilian J Telford
Department of Genetics, Environment and Evolution, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Dev Cell 14:457-9. 2008..A recent manuscript in Nature by Dunn and colleagues tackles this problem using massive sequence data sets from many taxa-the so-called "phylogenomic" approach... - Xenoturbellida: the fourth deuterostome phylum and the diet of wormsMaximilian J Telford
Department of Genetics, Evolution and Environment, University College London, London WC1E 6BT, UK
Genesis 46:580-6. 2008..I examine what this phylogenetic position for Xenoturbella can tell us about its own evolution and what light this might shine on the common ancestor of the deuterostomes and hence on the origins of the chordates... - Improving animal phylogenies with genomic dataMaximilian J Telford
Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Trends Genet 27:186-95. 2011..The wealth of genomic data now being produced promises that a well-resolved tree of the animal phyla will be available in the near future... - Invertebrate evolution: bringing order to the molluscan chaosMaximilian J Telford
Department of Genetics Evolution and Environment, University College London, Gower Street, London WC1E 6BT, UK
Curr Biol 21:R964-6. 2011..Two recent phylogenomic studies take an important step forward with intriguing implications for their evolution... - Animal phylogenyMaximilian J Telford
Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Curr Biol 16:R981-5. 2006 - Consideration of RNA secondary structure significantly improves likelihood-based estimates of phylogeny: examples from the bilateriaMaximilian J Telford
Department of Biology, University College London, London, UK
Mol Biol Evol 22:1129-36. 2005..Use of 16-state models also appears to reduce the Bayesian support given to certain biologically improbable groups found using standard 4-state models... - Ecdysozoan mitogenomics: evidence for a common origin of the legged invertebrates, the PanarthropodaOmar Rota-Stabelli
Department of Genetics, Evolution and Environment, University College London, London, United Kingdom
Genome Biol Evol 2:425-40. 2010..The same analyses also recover monophyly of traditionally recognized arthropod lineages such as Arachnida and of the highly debated clade Mandibulata... - Testing the new animal phylogeny: a phylum level molecular analysis of the animal kingdomSarah J Bourlat
Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Mol Phylogenet Evol 49:23-31. 2008..We also provide some resolution within the Lophotrochozoa, where we confirm support for a monophyletic clade of Echiura, Sipuncula and Annelida and surprising evidence of a close relationship between Brachiopoda and Nemertea... - Animal phylogeny: fatal attractionMaximilian J Telford
Department of Biology, University College London, Darwin Building, UK
Curr Biol 15:R296-9. 2005..MPhylogenetic analyses of hundreds of genes from model animals have placed flies closer to vertebrates than to nematodes; recent work suggests this may be due to an artefact known as long branch attraction... - A multi criterion approach for the selection of optimal outgroups in phylogeny: recovering some support for Mandibulata over Myriochelata using mitogenomicsOmar Rota-Stabelli
Research Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Mol Phylogenet Evol 48:103-11. 2008..Finally, we advocate a careful analysis and an objective choice of outgroup when dealing with derived sequences, such as mitochondrial genomes... - A congruent solution to arthropod phylogeny: phylogenomics, microRNAs and morphology support monophyletic MandibulataOmar Rota-Stabelli
Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Proc Biol Sci 278:298-306. 2011.... - Comparative gene expression in the heads of Drosophila melanogaster and Tribolium castaneum and the segmental affinity of the Drosophila hypopharyngeal lobesAndrew D Economou
Research Department of Genetics, Evolution and Environment, Darwin Building, University College London, Gower Street, London WC1E 6BT, UK
Evol Dev 11:88-96. 2009..We propose that the difficulties in interpreting the Drosophila head result from a topological shift in the Drosophila embryonic head, associated with the derived process of head involution... - Evolution of Hox3 and ftz in arthropods: insights from the crustacean Daphnia pulexDaniel Papillon
Department of Biology, Darwin Building, University College of London, Gower Street, London, WC1E 6BT, UK
Dev Genes Evol 217:315-22. 2007.... - Animal phylogeny: back to the coelomata?Maximilian J Telford
Department of Biology, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK
Curr Biol 14:R274-6. 2004..A fly-nematode grouping was becoming widely accepted, but recent comparisons of their genomes argue against this and link flies with the vertebrates instead... - Feeding ecology of Xenoturbella bocki (phylum Xenoturbellida) revealed by genetic barcodingSarah J Bourlat
Department of Biology, Darwin Building, University College London, Gower Street, London WC1E 6BT, UK Kristineberg Marine Research Station, Kristineberg 566, 45034 Fiskebackskil, Sweden
Mol Ecol Resour 8:18-22. 2008..In addition, these data suggest that Xenoturbella feeds specifically on bivalve prey from multiple species, possibly in the form of eggs and larvae... - The place of phylogeny and cladistics in Evo-Devo researchMaximilian J Telford
Department Zoology, Downing Street, Cambridge, CB2 3EJ, UK
Int J Dev Biol 47:479-90. 2003..All of these forms of inference are fundamental for comparative biology and of immediate importance to the practice of evolutionary developmental biology... - Evolution: affinity for arrow wormsMaximilian J Telford
Nature 431:254-6. 2004 - Systematic searches for molecular synapomorphies in model metazoan genomes give some support for Ecdysozoa after accounting for the idiosyncrasies of Caenorhabditis elegansRichard R Copley
Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK
Evol Dev 6:164-9. 2004..We conclude that the results from the intensively sampled ribosomal RNA genes supporting the Ecdysozoa hypothesis provide the most credible current estimates of metazoan phylogeny... - Mitogenomics and phylogenomics reveal priapulid worms as extant models of the ancestral EcdysozoanBonnie L Webster
Department of Zoology, The Natural History Museum, Cromwell Road, London SW7 5BD, UK
Evol Dev 8:502-10. 2006.... - Large-scale sequencing and the new animal phylogenyHervé Philippe
Canadian Institute for Advanced Research, Centre Robert Cedergren, Departement de Biochimie, Universite de Montreal, Succursale Centre Ville, Montreal, QC, Canada, H3C 3J7
Trends Ecol Evol 21:614-20. 2006..This approach counters both sources of error, gives the best hope of a well-resolved phylogeny of the animals and will act as a central resource for a carefully targeted genome sequencing programme... - Broad taxon and gene sampling indicate that chaetognaths are protostomesDavid Q Matus
Curr Biol 16:R575-6. 2006 - The evolution of hexapod engrailed-family genes: evidence for conservation and concerted evolutionAndrew D Peel
Laboratory for Development and Evolution, Department of Zoology, University Museum of Zoology, Cambridge, UK
Proc Biol Sci 273:1733-42. 2006..Finally, we hypothesize that the RS-motif is part of a serine-rich domain targeted for phosphorylation... - The complete mitochondrial genome of Flustrellidra hispida and the phylogenetic position of Bryozoa among the MetazoaAndrea Waeschenbach
Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
Mol Phylogenet Evol 40:195-207. 2006..Twenty-seven SNP sites were detected, the majority occurring in cox1 and nad5. With cox1 already established as a marker in bryozoan studies, we advocate the further testing of nad5... - Evolution: along came a sea spiderGraham E Budd
Nature 437:1099-102. 2005 - The multimeric beta-thymosin found in nematodes and arthropods is not a synapomorphy of the EcdysozoaMaximilian J Telford
Department of Zoology, University Museum of Zoology, Downing Street, Cambridge CB2 3EJ, UK
Evol Dev 6:90-4. 2004..Furthermore, the absence of the monomeric form from the genome of the deuterostome Ciona suggests that the absence of this character is an unreliable indicator of relationships... - The mitochondrial genome of Priapulus caudatus Lamarck (Priapulida: Priapulidae)Bonnie L Webster
Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, UK
Gene 389:96-105. 2007..Other arthropods and nematodes shared fewer gene boundaries but considerably more than the most similar non-ecdysozoan... - Xenoturbella is a deuterostome that eats molluscsSarah J Bourlat
University Museum of Zoology, Department of Zoology, Downing Street, Cambridge CB2 3EJ, UK
Nature 424:925-8. 2003..Here, using data from three genes, we show that the samples in these studies were contaminated by bivalve embryos eaten by Xenoturbella and that Xenoturbella is in fact a deuterostome related to hemichordates and echinoderms... - Combined large and small subunit ribosomal RNA phylogenies support a basal position of the acoelomorph flatwormsMaximilian J Telford
Laboratory for Development and Evolution, Department of Zoology, Downing Street, Cambridge CB2 3EJ, UK
Proc Biol Sci 270:1077-83. 2003..We conclude that the Nemertodermatida and Acoela are basal bilaterians and, owing to their unique body plan and embryogenesis, should be recognized as a separate phylum, the Acoelomorpha...