J L Teeling
Affiliation: University of Southampton
- Intracerebral immune complex formation induces inflammation in the brain that depends on Fc receptor interactionJessica L Teeling
Centre for of Biological Sciences, University of Southampton, Southampton General Hospital, UK
Acta Neuropathol 124:479-90. 2012..These observations may have important implications for the development of therapeutic antibodies directed against neuronal antigens used for therapeutic intervention in neurological diseases...
- Long-term impact of systemic bacterial infection on the cerebral vasculature and microgliaUrsula Püntener
Centre for Biological Sciences, University of Southampton, South Lab and Path Block, MP840, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK
J Neuroinflammation 9:146. 2012..In this study, we investigated the immune adaptation of microglia and brain vascular endothelial cells in response to systemic inflammation or bacterial infection...
- Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokinesJ L Teeling
CNS Inflammation Group, School of Biological Sciences, University of Southampton, Bassett Crescent East, UK
Brain Behav Immun 21:836-50. 2007..Taken together, these experiments suggest a key role for prostaglandins, rather than cytokines, in communicating to the brain...
- Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: underlying mechanismsJ L Teeling
CNS Inflammation Group, School of Biological Sciences, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
Neuroscience 158:1062-73. 2009..In this review we discuss the underlying mechanisms responsible for sickness behavior induced by systemic inflammation in the healthy brain and how they might be different in individuals with CNS pathology...
- The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1J L Teeling
CNS Inflammation Group, School of Biological Sciences, University of Southampton, Bassett Crescent East SO167PX, UK
Brain Behav Immun 24:409-19. 2010..Our results may have implications for novel therapeutic strategies to treat or prevent neurological diseases with an inflammatory component...