Research Topics
Genomes and GenesSpecies | Matthew J TaylorSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Lack of effect of ketamine on cortical glutamate and glutamine in healthy volunteers: a proton magnetic resonance spectroscopy studyMatthew J Taylor
Department of Psychiatry, University of Oxford, Oxford, UK
J Psychopharmacol 26:733-7. 2012..70). This study suggests that the gradual infusion of low-dose ketamine in antidepressant doses not cause changes in cortical glutamate or glutamine in healthy volunteers that are visible by proton MRS...
Normal glutamate but elevated myo-inositol in anterior cingulate cortex in recovered depressed patientsMatthew J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
J Affect Disord 119:186-9. 2009..Frontal Glx levels appear to be normalised after recovery from depression, but it is not known if this composite measure masks ongoing differences in glutamate or glutamine alone...
Lack of effect of citalopram on magnetic resonance spectroscopy measures of glutamate and glutamine in frontal cortex of healthy volunteersM J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
J Psychopharmacol 24:1217-21. 2010..This supports the potential for MRS in assessing neuroanatomically specific serotonin-glutamate interactions in the human brain...
Elevated cortical glutamate in young people at increased familial risk of depressionMatthew J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
Int J Neuropsychopharmacol 14:255-9. 2011..5, p=0.02). These findings suggest that abnormalities in glutamate neurotransmission may reflect a trait marker of vulnerability to depression...
Rapid onset of true antidepressant actionMatthew J Taylor
University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom
Curr Psychiatry Rep 9:475-9. 2007..About one third of the total treatment benefit over 6 weeks is evident by the end of the first week. Early response to antidepressants is not necessarily a placebo response...
Strategies for managing antidepressant-induced sexual dysfunction: a reviewMatthew J Taylor
University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom
Curr Psychiatry Rep 8:431-6. 2006..Many specific antidotes have been trialed but with lack of convincing benefit in most cases. However, where antidepressants cause erectile dysfunction, the use of sildenafil has the largest and most consistent evidence base...
Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysisMatthew J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, England
Arch Gen Psychiatry 63:1217-23. 2006..Selective serotonin reuptake inhibitors (SSRIs) are often described as having a delayed onset of effect in the treatment of depression. However, some trials have reported clinical improvement as early as the first week of treatment...
Strategies for managing antidepressant-induced sexual dysfunction: systematic review of randomised controlled trialsMatthew J Taylor
University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
J Affect Disord 88:241-54. 2005..This review was undertaken to assess the effectiveness of management strategies for sexual dysfunction caused by antidepressant medication...
Antidepressant response and the serotonin transporter gene-linked polymorphic regionMatthew J Taylor
Department of Psychiatry, University of Oxford, United Kingdom
Biol Psychiatry 68:536-43. 2010..Insertion or deletion of a 44-base pair-long region gives rise to short "S" and long "L" forms of the promoter region, the "S" form being associated with reduced serotonin transporter expression...
Short-term antidepressant treatment modulates amygdala response to happy facesRay Norbury
Psychopharmacology Research Unit PPRU, Department of Psychiatry, University of Oxford, Warneford Hospital, Neurosciences Building, Headington, Oxford, OX3 7JX, UK
Psychopharmacology (Berl) 206:197-204. 2009..These early effects of antidepressants may be an important component in the therapeutic effects of antidepressant treatment in patients with depression and anxiety...
Frontolimbic responses to emotional faces in young people at familial risk of depressionZola N Mannie
University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
J Affect Disord 130:127-32. 2011..The aim of the present study was to examine whether related neural abnormalities might be present in young people at increased familial risk of depression but with no personal history of illness...
Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trialsMatthew J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
J Psychopharmacol 18:251-6. 2004..It is currently unclear if this is the case both for people with normal folate levels, and for those with folate deficiency...
Early increase in marker of neuronal integrity with antidepressant treatment of major depression: 1H-magnetic resonance spectroscopy of N-acetyl-aspartateMatthew J Taylor
University Department of Psychiatry, Warneford Hospital Oxford, UK
Int J Neuropsychopharmacol 15:1541-6. 2012..01) or healthy controls (p<0.01). Our findings are consistent with the proposition that antidepressant treatment in depressed patients can produce early changes in neuronal integrity...
Long-term prophylaxis in bipolar disorderMatthew J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
CNS Drugs 20:303-10. 2006..Where available, a range of specific psychological interventions can be effective as an adjunct to medication.When discontinuation of prophylaxis is necessary, gradual tapering of dose over weeks or months is recommended...
Toward a neuropsychological theory of antidepressant drug action: increase in positive emotional bias after potentiation of norepinephrine activityCatherine J Harmer
Department of Psychiatry, Oxford University, Warneford Hospital, Oxford OX3 7JX, USA
Am J Psychiatry 160:990-2. 2003..Cognitive theories suggest that biases in information processing lead depressed patients to make unrealistically negative judgments about themselves and the world...
On "breathing: a sign of life..." Ekerholt and Bergland. Phys Ther. 2008;88:832-840Matthew J Taylor
Phys Ther 88:972. 2008
