Lydia Tabernero

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi request reprint Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity
    Amy E Theivagt
    Department of Chemistry, Illinois State University, Normal, Illinois 61790, USA
    Biochemistry 45:14397-406. 2006
  2. ncbi request reprint Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase
    Lydia Tabernero
    School of Biological Sciences, University of Manchester, Oxford Road, United Kingdom
    J Biol Chem 278:19933-8. 2003
  3. ncbi request reprint ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1
    Céline Tárrega
    Centro de Investigacion Principe Felipe, Valencia, Spain
    J Biol Chem 280:37885-94. 2005
  4. doi request reprint Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125
    Matthew L H Chu
    School of Pharmacy and Pharmaceutical Sciences, Stopford Building, University of Manchester, Manchester, UK
    J Biol Chem 283:21495-500. 2008

Collaborators

  • Victor W Rodwell
  • Matthew L H Chu
  • Amy E Theivagt
  • Céline Tárrega
  • Leonard M G Chavas
  • Kenneth T Douglas
  • Patrick A Eyers
  • Jon A Friesen
  • Elise N Amanti
  • Nicola J Beresford
  • Rafael Pulido
  • Jan Schepens
  • Rocío Cejudo-Marín
  • Carmen Blanco-Aparicio
  • Pablo Rios
  • Lieke van den Berk
  • Wiljan Hendriks

Detail Information

Publications4

  1. ncbi request reprint Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity
    Amy E Theivagt
    Department of Chemistry, Illinois State University, Normal, Illinois 61790, USA
    Biochemistry 45:14397-406. 2006
    ....
  2. ncbi request reprint Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase
    Lydia Tabernero
    School of Biological Sciences, University of Manchester, Oxford Road, United Kingdom
    J Biol Chem 278:19933-8. 2003
    ..We suggest that these differences might be exploited to develop selective class II inhibitors for use as antibacterial agents against pathogenic microorganisms...
  3. ncbi request reprint ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1
    Céline Tárrega
    Centro de Investigacion Principe Felipe, Valencia, Spain
    J Biol Chem 280:37885-94. 2005
    ....
  4. doi request reprint Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125
    Matthew L H Chu
    School of Pharmacy and Pharmaceutical Sciences, Stopford Building, University of Manchester, Manchester, UK
    J Biol Chem 283:21495-500. 2008
    ..These structures provide important insights into the interaction of this protein kinase with small molecules and suggest potential mechanisms for Mps1 regulation...