Research Topics
Genomes and GenesSpecies | Adam G TabakSummaryAffiliation: University College London Country: UK Publications
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Publications
Adiponectin trajectories before type 2 diabetes diagnosis: Whitehall II studyAdam G Tabak
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 35:2540-7. 2012..The role of adiponectin in the natural history of diabetes is not well characterized. We set out to characterize prediagnosis trajectories of adiponectin in individuals who develop type 2 diabetes...
Prediabetes: a high-risk state for diabetes developmentAdam G Tabak
Department of Epidemiology and Public Health, University College London, London, UK
Lancet 379:2279-90. 2012..For prediabetic individuals, lifestyle modification is the cornerstone of diabetes prevention, with evidence of a 40-70% relative-risk reduction. Accumulating data also show potential benefits from pharmacotherapy...- Changes in C-reactive protein levels before type 2 diabetes and cardiovascular death: the Whitehall II studyA G Tabák
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6 BT, UK
Eur J Endocrinol 163:89-95. 2010..This study describes CRP trajectories prior to type 2 diabetes onset and fatal CVD... - Low serum adiponectin predicts 10-year risk of type 2 diabetes and HbA1c independently of obesity, lipids, and inflammation: Whitehall II studyA G Tabák
Department of Epidemiology and Public Health, University College London, London WCE1 6BT, UK
Horm Metab Res 41:626-9. 2009..05). The observed robust, prospective associations support that adiponectin is an independent predictor of diabetes and the degree of glycaemic impairment... - The effect of paternal and maternal history of diabetes mellitus on the development of gestational diabetes mellitusA G Tabák
National Centre for Diabetes Care, Budapest, Hungary
J Endocrinol Invest 32:606-10. 2009..There is an ongoing debate whether maternal diabetes is a more important risk factor for gestational diabetes (GDM) development than paternal diabetes... - Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II studyAdam G Tabak
Department of Epidemiology and Public Health, University College London, London, UK
Lancet 373:2215-21. 2009..We aimed to characterise trajectories of fasting and postload glucose, insulin sensitivity, and insulin secretion in individuals who develop type 2 diabetes... - Antidepressant medication use and risk of hyperglycemia and diabetes mellitus: a noncausal association?Mika Kivimaki
Department of Epidemiology and Public Health, University College London, United Kingdom
Biol Psychiatry 70:978-84. 2011..To examine this, we assessed the associations of antidepressant use with change in glucose levels and incidence of undiagnosed and diagnosed diabetes... - Association between change in body composition and change in inflammatory markers: an 11-year follow-up in the Whitehall II StudyEleonor I Fransson
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, United Kingdom
J Clin Endocrinol Metab 95:5370-4. 2010..Obesity is associated with low-grade inflammation, but the long-term effects of weight change on inflammation are unknown... - Physical activity and inflammatory markers over 10 years: follow-up in men and women from the Whitehall II cohort studyMark Hamer
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, WC1E 6BT, UK
Circulation 126:928-33. 2012..We therefore examined the association between physical activity and inflammatory markers over a 10-year follow-up period... - Hyperglycemia, type 2 diabetes, and depressive symptoms: the British Whitehall II studyMika Kivimaki
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 32:1867-9. 2009..To examine the recent suggestion that impaired fasting glucose may protect against depression, whereas a diagnosis of diabetes might then result in depression... - Incremental predictive value of adding past blood pressure measurements to the Framingham hypertension risk equation: the Whitehall II StudyMika Kivimaki
Department of Epidemiology and Public Health, University College London, WC1E 6BT London, UK
Hypertension 55:1058-62. 2010..These data suggest that, despite the net reclassification improvement, the clinical use of adding repeat measures of blood pressure to the Framingham hypertension risk score may be limited... - Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II studyKim Bouillon
Department of Epidemiology and Public Health, University College London, London, UK
Heart 97:923-30. 2011..To examine the association of lipid-lowering drugs, change in diet and physical activity with a decline in low-density lipoprotein (LDL) cholesterol in middle age... - Overall diet history and reversibility of the metabolic syndrome over 5 years: the Whitehall II prospective cohort studyTasnime N Akbaraly
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 33:2339-41. 2010..We examined the impact of adherence to the Alternative Healthy Eating Index (AHEI), a set of dietary guidelines targeting major chronic diseases, on metabolic syndrome (MetS) reversion in a middle-aged population... - Does overall diet in midlife predict future aging phenotypes? A cohort studyTasnime Akbaraly
Department of Epidemiology and Public Health, University College London, London, UK INSERM, U1061 Montpellier, F 34093 France Université Montpellier I, Montpellier, F 34000, France Electronic address
Am J Med 126:411-419.e3. 2013..We examined whether diet, assessed in midlife, using dietary patterns and adherence to the Alternative Healthy Eating Index (AHEI), is associated with aging phenotypes, identified after a mean 16-year follow-up... - Arterial stiffness, physical function, and functional limitation: the Whitehall II StudyEric J Brunner
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Hypertension 57:1003-9. 2011..The nature of the link between arterial stiffness and quality of life in older people merits attention... - Metabolic syndrome over 10 years and cognitive functioning in late midlife: the Whitehall II studyTasnime N Akbaraly
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 33:84-9. 2010..We examined this association in late midlife, with particular focus on cumulative effects and the role of socioeconomic circumstances... - Antidepressant medication use, weight gain, and risk of type 2 diabetes: a population-based studyMika Kivimaki
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 33:2611-6. 2010..To examine antidepressant medication use as a risk factor for type 2 diabetes and weight gain... - Antidepressant use before and after the diagnosis of type 2 diabetes: a longitudinal modeling studyMika Kivimaki
Department of Epidemiology and Public Health, University College London, London, UK
Diabetes Care 33:1471-6. 2010..To examine antidepressant use before and after the diagnosis of diabetes... - Justice at work and metabolic syndrome: the Whitehall II studyDavid Gimeno
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Occup Environ Med 67:256-62. 2010..We aim to test whether high justice at work protects against metabolic syndrome... - Maternal glycemia and risk of large-for-gestational-age babies in a population-based screeningZsuzsa Kerenyi
National Centre for Diabetes Care, Budapest, Hungary
Diabetes Care 32:2200-5. 2009..We aimed to clarify the association of maternal glycemia across the whole distribution with birth weight and risk of LGA births in mothers with normal glucose tolerance... - Association between common mental disorder and obesity over the adult life courseMika Kivimaki
Department of Epidemiology and Public Health, University College London, WC1E 6BT London, UK
Br J Psychiatry 195:149-55. 2009..Prospective data on the association between common mental disorders and obesity are scarce, and the impact of ageing on this association is poorly understood... - Validating the Framingham Hypertension Risk Score: results from the Whitehall II studyMika Kivimaki
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, United Kingdom
Hypertension 54:496-501. 2009..5%; 95% CI: -2.5% to 1.5%). These data suggest that the Framingham hypertension risk score provides a valid tool with which to estimate near-term risk of developing hypertension... - Noninvasive evaluation of neural impairment in subjects with impaired glucose toleranceZsuzsanna Putz
1st Department of Medicine, Semmelweis University, Budapest, Hungary
Diabetes Care 32:181-3. 2009..To evaluate neural dysfunction in subjects with impaired glucose tolerance (IGT)... 
Myocardial infarction is associated with Spl binding site polymorphism of collagen type 1A1 geneGabor Speer
1st Department of Medicine, Semmelweis University, Budapest, Hungary
Acta Cardiol 61:321-5. 2006..In contrast, the normal coronary arteries do not express this type of collagen. Data have shown that the collagen type 1A1 (COL1A1) gene Sp1 binding site (-1245 G/T) polymorphism is associated with disturbed collagen protein production...- Serum erythropoietin level and mortality in kidney transplant recipientsMiklos Z Molnar
Institute of Pathophysiology, Semmelweis University, Nagyvarad ter 4, H 1089, Budapest, Hungary
Clin J Am Soc Nephrol 6:2879-86. 2011..We examined the association between serum erythropoietin levels and mortality among kidney transplant recipients...