Research Topics
Genomes and Genes
| Dylan SweetmanSummaryAffiliation: University of East Anglia Country: UK Publications
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Detail Information
Publications
FGF-4 signaling is involved in mir-206 expression in developing somites of chicken embryosDylan Sweetman
School of Biological Science, University of East Anglia, Norwich, United Kingdom
Dev Dyn 235:2185-91. 2006..Thus far, miRNAs have not been studied extensively in chicken embryos, and our results show that this system can complement other model organisms to investigate the regulation of many other miRNAs...
The migration of paraxial and lateral plate mesoderm cells emerging from the late primitive streak is controlled by different Wnt signalsDylan Sweetman
School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK
BMC Dev Biol 8:63. 2008..Here we use long-term video microscopy in chicken embryos to visualize the migration routes and movement behaviour of mesoderm progenitor cells as they emerge from the primitive streak (PS) between HH stages 7 and 10...- Expression of csal1 in pre limb-bud chick embryosDylan Sweetman
School of Biological Sciences, University of East Anglia, Norwich, UK
Int J Dev Biol 49:427-30. 2005..Expression was also seen in involuting mesoderm and later in presegmented paraxial mesoderm. We also describe expression in the ectoderm and neural plate of the early embryo and subsequent expression in the neural tube... - The vertebrate spalt genes in development and diseaseDylan Sweetman
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
Dev Biol 293:285-93. 2006..Here we review what is currently known about the role of spalt genes in vertebrate development and human disease... 
Specific requirements of MRFs for the expression of muscle specific microRNAs, miR-1, miR-206 and miR-133Dylan Sweetman
School of Biological Sciences, University of East Anglia, Norwich, Norfolk, NR4 7TJ, UK
Dev Biol 321:491-9. 2008..Taken together our results demonstrate differential requirements of distinct MRFs for the induction of microRNA gene expression during skeletal myogenesis...- MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesisKatarzyna Goljanek-Whysall
Department of Cell and Developmental Biology, University of East Anglia, Norwich NR4 7TJ, United Kingdom
Proc Natl Acad Sci U S A 108:11936-41. 2011.... - Regulation of multiple target genes by miR-1 and miR-206 is pivotal for C2C12 myoblast differentiationKatarzyna Goljanek-Whysall
Cell and Developmental Biology, School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK
J Cell Sci 125:3590-600. 2012..This indicates that the concerted downregulation of multiple microRNA targets is not only crucial to the skeletal muscle differentiation program but also serves to prevent alternative cell fate choices... - The conserved glutamine-rich region of chick csal1 and csal3 mediates protein interactions with other spalt family members. Implications for Townes-Brocks syndromeDylan Sweetman
School of Biological Sciences, University of East Anglia, Norwich, Norfolk NR4 7TJ, United Kingdom
J Biol Chem 278:6560-6. 2003..This could affect the transcriptional repressor activity of spalt and DNA binding. Spalt protein truncations could also affect the function of other spalt family members in various tissues... - Expression of avian prickle genes during early development and organogenesisOliver Cooper
School of Biological Sciences, University of East Anglia, Norwich, United Kingdom
Dev Dyn 237:1442-8. 2008..pk-2 was expressed in Hensen's node and neural ectoderm at early stages. In older embryos, pk-2 expression was restricted to ventromedial epithelial somites, except in the most recently formed somite pair, and limb bud mesenchyme... - High throughput sequencing of microRNAs in chicken somitesTina Rathjen
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
FEBS Lett 583:1422-6. 2009..One of the six new miRNAs is highly enriched in somite tissue suggesting that deep sequencing of other specific tissues has the potential to identify novel tissue specific miRNAs... - Wnt/Lef1 signaling acts via Pitx2 to regulate somite myogenesisMuhammad Abu-Elmagd
University of East Anglia, School of Biological Sciences, Norwich, NR4 7TJ Earlham Road, UK
Dev Biol 337:211-9. 2010.... - microRNAs in skeletal muscle differentiation and diseaseKatarzyna Goljanek-Whysall
School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK
Clin Sci (Lond) 123:611-25. 2012..We discuss the strategies that aim to develop novel therapies through modulating miRNA activity. In time, some of these approaches may become available to treat muscle-associated diseases... - Feedback interactions between MKP3 and ERK MAP kinase control scleraxis expression and the specification of rib progenitors in the developing chick somiteTerence Gordon Smith
School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK
Development 132:1305-14. 2005.... - Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from ArabidopsisDylan Sweetman
School of Biological Sciences, University of East Anglia, Earlham Road, Norwich, Norfolk, UK
FEBS Lett 581:4165-71. 2007..AtITPK4 differs from other family members in that it does not display inositol 3,4,5,6-tetrakisphosphate 1-kinase activity; rather, it displays inositol 1,4,5,6-tetrakisphosphate and inositol 1,3,4,5-tetrakisphosphate isomerase activity...